Cardinals vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for July 10

Odds updated as of 7:11 p.m.

MLB action on Thursday includes the St. Louis Cardinals playing the Washington Nationals.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cardinals vs Nationals Game Info

• St. Louis Cardinals (49-44) vs. Washington Nationals (38-54)
• Date: Thursday, July 10, 2025
• Time: 7:45 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and MASN

Cardinals vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-142) | WSH: (+120)
• Spread: STL: -1.5 (+138) | WSH: +1.5 (-166)
• Total: 9 -- Over: (-106) | Under: (-114)

Cardinals vs Nationals Probable Starting Pitchers

Probable Pitchers: Miles Mikolas (Cardinals) - 4-6, 5.26 ERA vs Mike Soroka (Nationals) - 3-6, 5.40 ERA

The Cardinals will give the ball to Miles Mikolas (4-6, 5.26 ERA), who is eyeing win No. 5 on the season, and the Nationals will counter with Mike Soroka (3-6, 5.40 ERA). Mikolas' team is 8-9-0 against the spread in his starts this season. Mikolas' team has won 50% of his starts when they are favored on the moneyline (2-2). The Nationals are 5-7-0 ATS in Soroka's 12 starts that had a set spread. The Nationals are 3-8 in Soroka's 11 starts this season that they were the underdog on the moneyline.

Cardinals vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (61.2%)

Cardinals vs Nationals Moneyline

• Looking at the moneyline for Cardinals-Nationals, St. Louis is the favorite at -142, and Washington is +120 playing on the road.

Cardinals vs Nationals Spread

• The Cardinals are hosting the Nationals and are favored by 1.5 runs on the spread. The Cardinals are +138 to cover the runline, with the Nationals being -166.

Cardinals vs Nationals Over/Under

• The Cardinals-Nationals game on July 10 has been given an over/under of 9 runs. The over is set at -106 and the under at -114.

Bet on St. Louis Cardinals vs. Washington Nationals on FanDuel today!

Cardinals vs Nationals Betting Trends

• The Cardinals have been victorious in 21, or 53.8%, of the 39 contests they have been chosen as favorites in this season.
• St. Louis has a record of 8-4 in contests when bookmakers favor them by -142 or more on the moneyline.
• The Cardinals and their opponents have gone over the total this season in 47 of their 90 opportunities.
• The Cardinals have posted a record of 49-41-0 against the spread this season.
• The Nationals have put together a 33-36 record in games they were listed as the moneyline underdog (winning 47.8% of those games).
• When playing as a moneyline underdog with odds of +120 or longer, Washington has a record of 20-27 (42.6%).
• The Nationals have had an over/under set by oddsmakers 87 times, and have combined with opponents to go over the total in 48 of those games (48-38-1).
• The Nationals have covered 52.9% of their games this season, going 46-41-0 ATS.

Cardinals Player Leaders

• Brendan Donovan leads St. Louis OPS (.801) this season. He has a .294 batting average, an on-base percentage of .367, and a slugging percentage of .434.
• Among the qualified hitters in baseball, his batting average ranks 14th, his on-base percentage ranks 26th, and he is 78th in slugging.
• Nolan Arenado has 13 doubles, a triple, 10 home runs and 24 walks. He's batting .244 and slugging .389 with an on-base percentage of .303.
• He is 116th in batting average, 127th in on-base percentage and 113th in slugging in MLB.
• Lars Nootbaar is batting .229 with a .384 slugging percentage and 37 RBI this year.
• Nootbaar takes a two-game hitting streak into this matchup. In his last five games he is batting .278 with a double, a home run, a walk and two RBIs.
• Alec Burleson leads St. Louis in total hits (80) this season while batting .290 with 26 extra-base hits.
• Burleson heads into this game on a two-game hitting streak. In his last five games he is batting .278 with a double, a home run, three walks and three RBIs.

Nationals Player Leaders

• James Wood has 99 hits with a .388 on-base percentage and a .551 slugging percentage, all club-highs for the Nationals. He's batting .287.
• Including all the qualified hitters in the majors, his batting average ranks 24th, his on-base percentage is fifth, and he is 10th in slugging.
• Wood brings a three-game hitting streak into this matchup. In his last five games he is hitting .167 with a home run, a walk and two RBIs.
• C.J. Abrams is hitting .287 with 19 doubles, three triples, 12 home runs and 24 walks. He's slugging .481 with an on-base percentage of .355.
• He is currently 24th in batting average, 39th in on-base percentage and 35th in slugging percentage among all qualifying hitters.
• Luis Garcia has 19 doubles, seven home runs and 17 walks while batting .266.
• Nathaniel Lowe has 14 doubles, two triples, 14 home runs and 33 walks while hitting .235.

Cardinals vs Nationals Head to Head

• 7/9/2025: 8-2 WSH (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/11/2025: 6-1 STL (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/10/2025: 4-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/9/2025: 10-0 STL (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 7/28/2024: 4-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/27/2024: 14-3 WSH (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 7/26/2024: 10-8 WSH (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 7/8/2024: 6-0 STL (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/7/2024: 8-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/6/2024: 14-6 WSH (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!