Astros vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for July 7

Odds updated as of 7:12 a.m.
The MLB's Monday slate includes the Houston Astros taking on the Cleveland Guardians.
We've got you covered, in terms of the vital information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.
Astros vs Guardians Game Info
- Houston Astros (55-35) vs. Cleveland Guardians (40-48)
- Date: Monday, July 7, 2025
- Time: 8:10 p.m. ET
- Venue: Daikin Park -- Houston, Texas
- Coverage: SCHN and CLEG
Astros vs Guardians Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: HOU: (-162) | CLE: (+136)
- Spread: HOU: -1.5 (+130) | CLE: +1.5 (-156)
- Total: 7.5 -- Over: (+102) | Under: (-124)
Astros vs Guardians Probable Starting Pitchers
Probable Pitchers: Colton Gordon (Astros) - 3-1, 4.37 ERA vs Tanner Bibee (Guardians) - 4-9, 4.10 ERA
The Astros will give the nod to Colton Gordon (3-1, 4.37 ERA), who is eyeing win No. 4 on the season, and the Guardians will counter with Tanner Bibee (4-9, 4.10 ERA). Gordon's team is 5-4-0 against the spread in his starts this season. Gordon's team has a record of 3-2 this season when he starts and they are the favorite on the moneyline. The Guardians have an 8-8-0 record against the spread in Bibee's starts. The Guardians have a 2-6 record in Bibee's eight starts this season when they were the underdog on the moneyline.
Astros vs Guardians Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (68.4%)
Astros vs Guardians Moneyline
- Houston is the favorite, -162 on the moneyline, while Cleveland is a +136 underdog on the road.
Astros vs Guardians Spread
- The Guardians are +1.5 on the spread (-156 to cover), and Houston is +130 to cover the runline.
Astros vs Guardians Over/Under
- A combined run total of 7.5 has been set for Astros-Guardians on July 7, with the over at +102 and the under at -124.
Bet on Houston Astros vs. Cleveland Guardians on FanDuel today!
Astros vs Guardians Betting Trends
- The Astros have been victorious in 37, or 60.7%, of the 61 contests they have been chosen as favorites in this season.
- Houston has a record of 11-7 in contests when oddsmakers favor them by -162 or more on the moneyline.
- The Astros' games have gone over the total in 36 of their 89 opportunities.
- The Astros are 47-42-0 against the spread in their 89 games that had a posted line this season.
- The Guardians have won 21 of the 56 games they were the moneyline underdog this season (37.5%).
- Cleveland has a 4-12 record (winning only 25% of its games) when it has played as a moneyline underdog of +136 or longer.
- In the 86 games bookmakers have set an over/under for the Guardians, they have combined with opponents to go over the total 36 times (36-47-3).
- The Guardians have collected a 42-44-0 record ATS this season (covering 48.8% of the time).
Astros Player Leaders
- Isaac Paredes is hitting .257 with 12 doubles, a triple, 18 home runs and 44 walks. He has an on-base percentage of .356 while slugging .467.
- Among all qualifying hitters in baseball, he is 81st in batting average, 35th in on-base percentage, and 45th in slugging.
- Paredes will look for his sixth straight game with a hit in this matchup. During his last five outings he is hitting .333 with two doubles, a home run, a walk and two RBIs.
- Jose Altuve has 12 doubles, a triple, 16 home runs and 31 walks. He's batting .272 and slugging .457 with an on-base percentage of .332.
- Among qualifying hitters, he ranks 50th in batting average, 71st in on-base percentage and 52nd in slugging percentage.
- Altuve heads into this game looking to extend his five-game hit streak. In his last five games he is hitting .500 with two doubles, a triple, three home runs, three walks and 10 RBIs.
- Jake Meyers has 89 hits this season and has a slash line of .308/.369/.405.
- Yainer Diaz has been key for Houston with 75 hits, an OBP of .280 plus a slugging percentage of .411.
- Diaz brings a five-game hitting streak into this matchup. During his last five outings he is batting .412 with two doubles, two home runs, two walks and three RBIs.
Guardians Player Leaders
- Jose Ramirez has racked up 95 hits with a .360 on-base percentage, leading the Guardians in both statistics. He's batting .297 and slugging .484.
- He is 13th in batting average, 29th in on-base percentage and 32nd in slugging percentage among all qualified hitters in the big leagues.
- Steven Kwan leads his team with a .419 slugging percentage. He has a batting average of .298 with an on-base percentage of .358.
- He ranks 11th in batting average, 31st in on-base percentage and 86th in slugging percentage in the majors.
- Carlos Santana is batting .235 with seven doubles, 10 home runs and 39 walks.
- Kyle Manzardo is batting .217 with 11 doubles, two triples, 13 home runs and 25 walks.
Astros vs Guardians Head to Head
- 6/8/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
- 6/7/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
- 6/6/2025: 4-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
- 9/28/2024: 4-3 HOU (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
- 9/27/2024: 5-2 HOU (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
- 5/2/2024: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
- 5/1/2024: 3-2 CLE (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
- 4/30/2024: 10-9 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
- 8/2/2023: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
- 8/1/2023: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!