Astros vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for July 7

Odds updated as of 8:14 p.m.

The Houston Astros will take on the Cleveland Guardians in MLB action on Monday.

We've got you covered, in terms of the vital information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Astros vs Guardians Game Info

• Houston Astros (55-35) vs. Cleveland Guardians (40-48)
• Date: Monday, July 7, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and CLEG

Astros vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-126) | CLE: (+108)
• Spread: HOU: -1.5 (+160) | CLE: +1.5 (-194)
• Total: 7.5 -- Over: (-104) | Under: (-118)

Astros vs Guardians Probable Starting Pitchers

Probable Pitchers: Colton Gordon (Astros) - 3-1, 4.37 ERA vs Tanner Bibee (Guardians) - 4-9, 4.10 ERA

This contest's pitching matchup is set, as the Astros will send Colton Gordon (3-1) to the mound, while Tanner Bibee (4-9) will answer the bell for the Guardians. Gordon and his team have a record of 5-4-0 against the spread when he starts. Gordon's team has a record of 3-2 this season when he starts and they are the favorite on the moneyline. The Guardians have an 8-8-0 ATS record in Bibee's 16 starts that had a set spread. The Guardians have a 2-6 record in Bibee's eight starts this season when they were the moneyline underdog.

Astros vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (71.4%)

Astros vs Guardians Moneyline

• Cleveland is the underdog, +108 on the moneyline, while Houston is a -126 favorite at home.

Astros vs Guardians Spread

• The Astros are hosting the Guardians and are favored by 1.5 runs on the spread. The Astros are +160 to cover the runline, with the Guardians being -194.

Astros vs Guardians Over/Under

• Astros versus Guardians, on July 7, has an over/under of 7.5, with the over being -104 and the under -118.

Bet on Houston Astros vs. Cleveland Guardians on FanDuel today!

Astros vs Guardians Betting Trends

• The Astros have been favorites in 61 games this season and have come away with the win 37 times (60.7%) in those contests.
• Houston has a record of 26-15 in contests when bookmakers favor them by -126 or more on the moneyline.
• The Astros' games have gone over the total in 36 of their 89 opportunities.
• The Astros have an against the spread mark of 47-42-0 in 89 games with a line this season.
• The Guardians have gone 21-35 in games they were the underdog on the moneyline (winning 37.5% of those games).
• When it has played as a moneyline underdog with odds of +108 or longer, Cleveland has a record of 9-25 (26.5%).
• The Guardians have played in 86 games with an over/under set, and have combined with opponents to go over the total 36 times (36-47-3).
• The Guardians have put together a 42-44-0 record ATS this season (covering 48.8% of the time).

Astros Player Leaders

• Isaac Paredes has 12 doubles, a triple, 18 home runs and 44 walks while hitting .257. He has an on-base percentage of .356 and a slugging percentage of .467.
• Among all qualified batters in MLB, he is 81st in batting average, 35th in on-base percentage, and 45th in slugging.
• Paredes will look for his sixth straight game with a hit in this matchup. In his last five games he is batting .333 with two doubles, a home run, a walk and two RBIs.
• Jose Altuve has 12 doubles, a triple, 16 home runs and 31 walks. He's batting .272 and slugging .457 with an on-base percentage of .332.
• Among all qualified, he is 50th in batting average, 71st in on-base percentage and 52nd in slugging percentage.
• Altuve heads into this matchup looking to extend his five-game hit streak. In his last five games he is batting .500 with two doubles, a triple, three home runs, three walks and 10 RBIs.
• Jake Meyers is batting .308 with a .405 slugging percentage and 21 RBI this year.
• Yainer Diaz has 12 home runs, 37 RBI and a batting average of .248 this season.
• Diaz has safely hit in five straight games. During his last five outings he is batting .412 with two doubles, two home runs, two walks and three RBIs.

Guardians Player Leaders

• Jose Ramirez has an on-base percentage of .360 and has 95 hits, both team-best numbers for the Guardians. He's batting .297 and slugging .484.
• He ranks 13th in batting average, 29th in on-base percentage and 32nd in slugging percentage among all qualified hitters in the majors.
• Steven Kwan is slugging .419 to pace his team. He has a batting average of .298 with an on-base percentage of .358.
• He is currently 11th in batting average, 31st in on-base percentage and 86th in slugging percentage among all qualifying hitters.
• Carlos Santana is batting .235 with seven doubles, 10 home runs and 39 walks.
• Kyle Manzardo is batting .217 with 11 doubles, two triples, 13 home runs and 25 walks.

Astros vs Guardians Head to Head

• 6/8/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/7/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/6/2025: 4-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/28/2024: 4-3 HOU (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/27/2024: 5-2 HOU (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/2/2024: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/1/2024: 3-2 CLE (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/30/2024: 10-9 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/2/2023: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/1/2023: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!