Astros vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 10

Odds updated as of 9:11 p.m.

Monday's slate in the MLB includes a matchup between the Houston Astros and the San Francisco Giants.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Giants Game Info

• Houston Astros (60-59) vs. San Francisco Giants (49-69)
• Date: Monday, August 10, 2026
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and SCHN

Astros vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-142) | SF: (+132)
• Spread: HOU: -1.5 (+118) | SF: +1.5 (-142)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Astros vs Giants Probable Starting Pitchers

Probable Pitchers: Hayden Wesneski (Astros) - 2-0, 3.86 ERA vs Blade Tidwell (Giants) - 0-0, 3.18 ERA

The Astros will give the nod to Hayden Wesneski (2-0, 3.86 ERA), who is eyeing win No. 3 on the season, and the Giants will turn to Blade Tidwell. Wesneski has a record of 2-0-0 ATS in two starts with a spread this season. Wesneski's team is 2-0 this season when he starts and they're favored on the moneyline. Tidwell has started only one game with a set spread, which the Giants covered. The Giants were the moneyline underdog for one Tidwell start this season -- they lost.

Astros vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (53.3%)

Astros vs Giants Moneyline

• Houston is a -142 favorite on the moneyline, while San Francisco is a +132 underdog at home.

Astros vs Giants Spread

• The Astros are 1.5-run road favorites on the runline against the Giants. The Astros are +118 to cover, and the Giants are -142.

Astros vs Giants Over/Under

• Astros versus Giants, on Aug. 10, has an over/under of 8.5, with the over being -104 and the under -118.

Bet on Houston Astros vs. San Francisco Giants on FanDuel today!

Astros vs Giants Betting Trends

• The Astros have come away with 23 wins in the 45 contests they have been listed as the favorites in this season.
• Houston has a record of 5-12 when favored by -142 or more this year.
• Contests with the Astros have gone over the total set by bookmakers in 64 of 119 chances this season.
• The Astros are 59-60-0 against the spread in their 119 games with a line set by sportsbooks this season.
• The Giants have gone 26-48 in games they were listed as the moneyline underdog (winning 35.1% of those games).
• When it has played as a moneyline underdog with odds of +132 or longer, San Francisco has gone 9-10 (47.4%).
• The Giants have played in 115 games with an over/under set, and have combined with opponents to go over the total 53 times (53-53-9).
• The Giants have collected a 52-63-0 record ATS this season.

Astros Player Leaders

• Yordan Alvarez has 137 hits and an OBP of .435 to go with a slugging percentage of .624. All three of those stats are tops among Houston hitters this season. He has a .322 batting average, as well.
• Among qualified hitters, he is first in batting average, his on-base percentage ranks first, and he is first in slugging.
• Isaac Paredes has 20 doubles, a triple, 15 home runs and 45 walks. He's batting .251 and slugging .415 with an on-base percentage of .345.
• His batting average is 80th among qualified players, his on-base percentage 51st, and his slugging percentage 86th.
• Christian Walker has 102 hits this season and has a slash line of .240/.319/.456.
• Jeremy Pena has been key for Houston with 83 hits, an OBP of .357 plus a slugging percentage of .487.

Giants Player Leaders

• Jung Hoo Lee has put up a team-high OBP (.334) and slugging percentage (.440). He's batting .298.
• Including all the qualified players in MLB, his batting average places him ninth, his on-base percentage ranks 71st, and he is 59th in slugging.
• Rafael Devers is hitting .249 with 27 doubles, a triple, 24 home runs and 48 walks. He's slugging .475 with an on-base percentage of .321.
• Including all qualifying hitters, he ranks 84th in batting average, 89th in on-base percentage and 28th in slugging percentage.
• Willy Adames is batting .222 with 24 doubles, a triple, 19 home runs and 34 walks.
• Bryce Eldridge is batting .248 with 14 doubles, 11 home runs and 39 walks.

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