Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 3:12 p.m.

The MLB slate on Saturday includes the Houston Astros facing the Athletics.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Astros vs Athletics Game Info

• Houston Astros (29-36) vs. Athletics (30-33)
• Date: Saturday, June 6, 2026
• Time: 4:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-CA

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-108) | OAK: (-108)
• Spread: HOU: +1.5 (-182) | OAK: -1.5 (+150)
• Total: 8.5 -- Over: (-128) | Under: (+104)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Tatsuya Imai (Astros) - 2-3, 5.52 ERA vs Kade Morris (Athletics) - 0-0, 0.00 ERA

The Astros will give the nod to Tatsuya Imai (2-3, 5.52 ERA), who is eyeing win No. 3 on the season, and the Athletics will turn to Kade Morris. Imai's team is 3-4-0 against the spread this season in his starts. Imai's team won his only start as a favorite this season. Morris did not pitch as a moneyline underdog a season ago.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (50.5%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -108 favorite, while the Athletics are a -108 underdog on the road.

Astros vs Athletics Spread

Astros vs Athletics Over/Under

• Astros versus Athletics on June 6 has an over/under of 8.5 runs, with the odds on the over -128 and the under set at +104.

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Astros vs Athletics Betting Trends

• The Astros have been chosen as favorites in 17 games this year and have walked away with the win five times (29.4%) in those games.
• This season, the Astros have come away with a win seven times in 20 chances when named as a favorite of at least -108 or better on the moneyline.
• The Astros and their opponents have hit the over in 35 of their 65 games with a total this season.
• The Astros have an against the spread mark of 30-35-0 in 65 games with a line this season.
• The Athletics have won 52.4% of the games this season they were the moneyline underdog (22-20).
• The Athletics have a record of 22-20 in games they have played as a moneyline underdog with odds of -108 or longer (52.4%).
• The Athletics have combined with their opponents to hit the over on the total 31 times this season for a 31-31-1 record against the over/under.
• The Athletics have collected a 31-32-0 record against the spread this season (covering 49.2% of the time).

Astros Player Leaders

• Yordan Alvarez has 73 hits and an OBP of .429 to go with a slugging percentage of .645. All three of those stats lead Houston hitters this season. He has a .316 batting average, as well.
• Among qualified batters, he is sixth in batting average, his on-base percentage ranks second, and he is second in slugging.
• Alvarez will look for his fifth straight game with a hit in this matchup. In his last five games he is hitting .444 with a double, a home run, three walks and five RBIs.
• Christian Walker has 10 doubles, a triple, 16 home runs and 22 walks. He's batting .248 and slugging .500 with an on-base percentage of .321.
• He is 88th in batting average, 100th in on-base percentage and 28th in slugging among qualified hitters.
• Walker enters this matchup looking to extend his four-game hit streak. During his last five outings he is hitting .190 with a triple, a walk and three RBIs.
• Isaac Paredes is batting .241 with a .415 slugging percentage and 32 RBI this year.
• Paredes has recorded at least one base hit in three straight games. In his last five games he is hitting .294 with a double, three home runs, three walks and eight RBIs.
• Cam Smith has six home runs, 24 RBI and a batting average of .212 this season.

Athletics Player Leaders

• Nick Kurtz a has .438 on-base percentage to pace the Athletics. He's batting .282 while slugging .495.
• He ranks 33rd in batting average, first in on-base percentage and 31st in slugging percentage among all qualified batters in the majors.
• Shea Langeliers' 66 hits and .547 slugging percentage are both team-highs. He has a batting average of .284 with an on-base percentage of .353.
• He is currently 29th in batting average, 50th in on-base percentage and 10th in slugging percentage among all qualified hitters.
• Tyler Soderstrom is hitting .229 with 17 doubles, two triples, eight home runs and 29 walks.
• Carlos Cortes is hitting .315 with nine doubles, a triple, five home runs and 20 walks.

Astros vs Athletics Head to Head

• 6/5/2026: 5-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/5/2026: 12-10 OAK (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/4/2026: 11-0 HOU (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/3/2026: 11-4 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/25/2025: 11-5 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/24/2025: 6-0 OAK (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/23/2025: 5-1 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/27/2025: 7-1 OAK (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/26/2025: 5-1 OAK (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/25/2025: 15-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)

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