Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for June 5

Odds updated as of 7:12 p.m.

The Houston Astros are among the MLB squads busy on Friday, up against the Athletics.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Athletics Game Info

• Houston Astros (28-36) vs. Athletics (30-32)
• Date: Friday, June 5, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-CA

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-108) | OAK: (-108)
• Spread: HOU: +1.5 (-176) | OAK: -1.5 (+146)
• Total: 9 -- Over: (-122) | Under: (+100)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Peter Lambert (Astros) - 4-4, 3.77 ERA vs Jack Perkins (Athletics) - 2-2, 5.46 ERA

The Astros will give the nod to Peter Lambert (4-4) against the Athletics and Jack Perkins (2-2). Lambert and his team have a record of 4-4-0 against the spread when he starts. Lambert's team lost his only start as a favorite this season. Last season when Perkins pitched his team went 3-1-0 against the spread. Perkins and his team won both games he appeared in when they were the moneyline underdog a season ago.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (53%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -108 favorite, while the Athletics are a -108 underdog on the road.

Astros vs Athletics Spread

Astros vs Athletics Over/Under

• The over/under for the Astros versus Athletics game on June 5 has been set at 9, with -122 odds on the over and +100 odds on the under.

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Astros vs Athletics Betting Trends

• The Astros have come away with five wins in the 17 contests they have been listed as the favorites in this season.
• This year, the Astros have won six of 19 games when listed as at least -108 or better on the moneyline.
• The Astros and their opponents have hit the over in 35 of their 64 games with a total this season.
• The Astros have an against the spread mark of 29-35-0 in 64 games with a line this season.
• The Athletics have won 52.4% of the games this season they were the moneyline underdog (22-20).
• When they have played as a moneyline underdog with odds of -108 or longer, the Athletics have a record of 22-20 (52.4%).
• The Athletics have combined with their opponents to go over the total 31 times this season for a 31-30-1 record against the over/under.
• The Athletics have gone 31-31-0 against the spread this season.

Astros Player Leaders

• Yordan Alvarez leads Houston in OBP (.428), slugging percentage (.649) and total hits (72) this season. He has a .316 batting average.
• Among qualified hitters, he ranks sixth in batting average, his on-base percentage ranks second, and he is first in slugging.
• Alvarez hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .474 with two doubles, a home run, three walks and five RBIs.
• Christian Walker is batting .247 with 10 doubles, 16 home runs and 21 walks, while slugging .494 with an on-base percentage of .318.
• Among qualifying batters, his batting average places him 89th, his on-base percentage 102nd, and his slugging percentage 30th.
• Walker enters this matchup looking to extend his three-game hit streak. During his last five outings he is hitting .182 with a home run and five RBIs.
• Isaac Paredes is batting .238 with a .400 slugging percentage and 28 RBI this year.
• Paredes brings a two-game hitting streak into this game. In his last five games he is batting .278 with two doubles, two home runs, three walks and six RBIs.
• Cam Smith is batting .216 with a .307 OBP and 24 RBI for Houston this season.

Athletics Player Leaders

• Shea Langeliers has racked up 66 hits with a .557 slugging percentage, both team-best stats for the Athletics. He's batting .289 and with an on-base percentage of .358.
• Including all the qualified hitters in the big leagues, he is 23rd in batting average, 41st in on-base percentage and sixth in slugging percentage.
• Nick Kurtz paces his team with a .437 OBP. He has a batting average of .284 while slugging .500.
• Including all qualified hitters, his batting average puts him 32nd, his on-base percentage ranks first, and he is 29th in slugging.
• Tyler Soderstrom has 17 doubles, two triples, eight home runs and 27 walks while batting .231.
• Carlos Cortes is hitting .322 with nine doubles, a triple, five home runs and 19 walks.

Astros vs Athletics Head to Head

• 4/5/2026: 12-10 OAK (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/4/2026: 11-0 HOU (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/3/2026: 11-4 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/25/2025: 11-5 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/24/2025: 6-0 OAK (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/23/2025: 5-1 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/27/2025: 7-1 OAK (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/26/2025: 5-1 OAK (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/25/2025: 15-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/24/2025: 5-2 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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