Yankees vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 5

Odds updated as of 6:13 p.m.

The Friday schedule in MLB includes a matchup between the New York Yankees and the Boston Red Sox.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Red Sox Game Info

• New York Yankees (37-25) vs. Boston Red Sox (26-35)
• Date: Friday, June 5, 2026
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: YES and NESN

Yankees vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-144) | BOS: (+122)
• Spread: NYY: -1.5 (+142) | BOS: +1.5 (-172)
• Total: 8 -- Over: (-110) | Under: (-110)

Yankees vs Red Sox Probable Starting Pitchers

Probable Pitchers: Ryan Weathers (Yankees) - 2-3, 3.52 ERA vs Sonny Gray (Red Sox) - 6-1, 3.06 ERA

The Yankees will look to Ryan Weathers (2-3) against the Red Sox and Sonny Gray (6-1). Weathers and his team have a record of 4-6-0 against the spread when he starts. Weathers' team has a record of 5-5 this season when he starts and they are the favorite on the moneyline. The Red Sox have a 7-3-0 record against the spread in Gray's starts. The Red Sox were the underdog on the moneyline for one Gray start this season -- they won.

Yankees vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (56.8%)

Yankees vs Red Sox Moneyline

• Boston is a +122 underdog on the moneyline, while New York is a -144 favorite at home.

Yankees vs Red Sox Spread

• The Yankees are 1.5-run home favorites on the runline against the Red Sox. The Yankees are +142 to cover, and the Red Sox are -172.

Yankees vs Red Sox Over/Under

• The over/under for Yankees-Red Sox on June 5 is 8. The over is -110, and the under is -110.

Bet on New York Yankees vs. Boston Red Sox on FanDuel today!

Yankees vs Red Sox Betting Trends

• The Yankees have been victorious in 34, or 61.8%, of the 55 contests they have been chosen as favorites in this season.
• New York has a record of 22-13 in contests when oddsmakers favor them by -144 or more on the moneyline.
• The Yankees' games have gone over the total in 27 of their 59 opportunities.
• The Yankees have an against the spread record of 29-30-0 in 59 games with a line this season.
• The Red Sox have won eight of the 21 games they were the moneyline underdog this season (38.1%).
• Boston has a record of 1-4 when it has played as a moneyline underdog with odds of +122 or longer (20%).
• The Red Sox have played in 61 games with a set over/under, and have combined with their opponents to go over the total 28 times (28-32-1).
• The Red Sox have put together a 26-35-0 record against the spread this season (covering 42.6% of the time).

Yankees Player Leaders

• Ben Rice leads New York in OBP (.393), slugging percentage (.638) and total hits (62) this season. He has a .300 batting average.
• Among qualifying hitters in MLB, his batting average ranks 16th, his on-base percentage ranks 11th, and he is second in slugging.
• Cody Bellinger is hitting .273 with 13 doubles, three triples, eight home runs and 38 walks, while slugging .468 with an on-base percentage of .373.
• Among all qualifying players, he is 48th in batting average, 27th in on-base percentage and 43rd in slugging percentage.
• Trent Grisham has 42 hits this season and has a slash line of .212/.331/.379.
• Jazz Chisholm is batting .238 with a .313 OBP and 22 RBI for New York this season.

Red Sox Player Leaders

• Willson Contreras has accumulated 61 hits with a .392 on-base percentage, leading the Red Sox in both statistics. He's batting .295 and slugging .527.
• Including all the qualifying hitters in MLB, he is 18th in batting average, 13th in on-base percentage and 15th in slugging percentage.
• Wilyer Abreu paces his team with a .433 slugging percentage. He has a batting average of .283 with an on-base percentage of .347.
• His batting average is 34th among all qualified players, his on-base percentage is 60th, and he is 70th in slugging.
• Jarren Duran has nine doubles, two triples, 10 home runs and 18 walks while hitting .215.
• Ceddanne Rafaela is batting .286 with 12 doubles, two triples, five home runs and 13 walks.

Yankees vs Red Sox Head to Head

• 4/23/2026: 4-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/22/2026: 4-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/21/2026: 4-0 NYY (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 10/2/2025: 4-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 10/1/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/30/2025: 3-1 BOS (Favorite: Yankees, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/14/2025: 6-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 9/13/2025: 5-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/12/2025: 4-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/24/2025: 7-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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