Astros vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for March 27

Odds updated as of 8:12 p.m.

On Friday in MLB, the Houston Astros are playing the Los Angeles Angels.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Angels Game Info

• Houston Astros (0-1) vs. Los Angeles Angels (1-0)
• Date: Friday, March 27, 2026
• Time: 8:15 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: Apple TV+

Astros vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-146) | LAA: (+124)
• Spread: HOU: -1.5 (+146) | LAA: +1.5 (-178)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Astros vs Angels Probable Starting Pitchers

Probable Pitchers: Mike Burrows (Astros) - 0-0, 0.00 ERA vs Yusei Kikuchi (Angels) - 0-0, 0.00 ERA

The Astros will give the nod to Mike Burrows versus the Angels and Yusei Kikuchi. Burrows and his team were 11-8-0 against the spread when he pitched last season. Burrows and his team won as favorites in 50% of his six appearances last season with a moneyline. Last season Kikuchi and his team went 18-15-0 against the spread when he pitched. Kikuchi and his team went 7-14 in games he appeared in when they were the moneyline underdog a season ago.

Astros vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (65.7%)

Astros vs Angels Moneyline

• The Astros vs Angels moneyline has Houston as a -146 favorite, while Los Angeles is a +124 underdog on the road.

Astros vs Angels Spread

• The Angels are at the Astros, and are +1.5 on the runline. The Angels are +146 to cover the spread, and the Astros are -178.

Astros vs Angels Over/Under

• An over/under of 8.5 has been set for Astros-Angels on March 27, with the over being -115 and the under -105.

Bet on Houston Astros vs. Los Angeles Angels on FanDuel today!

Astros vs Angels Betting Trends

• The Astros won in 53, or 53.5%, of the 99 contests they were named as odds-on favorites in the last year.
• Last year, Houston won 20 of 36 games when listed as at least -146 on the moneyline.
• The Astros and their opponents hit the over in 72 of their 161 games with a total last season.
• The Angels were the underdog on the moneyline 121 times last season. They finished 52-69 in those games.
• When it played as a moneyline underdog with odds of +124 or longer last year, Los Angeles went 30-37 (44.8%).
• The Angels combined with their opponents to hit the over on the total 84 times last season for an 84-71-5 record against the over/under.

Astros Player Leaders

• Jose Altuve had a .442 slugging percentage last season thanks to 51 extra-base hits.
• Jeremy Pena finished with an OBP of .363 and 150 total hits.
• Last season, Yainer Diaz finished with 20 home runs, 70 RBI and a batting average of .256 last season.
• Christian Walker slashed .238/.297/.421 and finished with an OPS of .717.

Angels Player Leaders

• Jo Adell racked up 124 hits with a batting average of .236 last season.
• Nolan Schanuel slugged .389 while batting .264.
• Zach Neto accumulated a slugging percentage of .474 and a batting average of .257 last season.
• Mike Trout had an OBP of .359 while batting .232.

Astros vs Angels Head to Head

• 3/26/2026: 3-0 LAA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/28/2025: 6-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/27/2025: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/26/2025: 4-3 LAA (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/1/2025: 8-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/31/2025: 3-0 LAA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/30/2025: 4-1 LAA (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 8/29/2025: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/22/2025: 8-7 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/21/2025: 9-1 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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