76ers vs. Knicks Eastern Semifinals Prediction, Odds, Picks, Best Bets for May 10

76ers vs. Knicks Game Info

• Date: Sunday, May 10, 2026
• Time: 3:30 p.m. ET
• Venue: Xfinity Mobile Arena -- Philadelphia, Pennsylvania
• Coverage: ABC

The New York Knicks bring a 3-0 lead into a decisive Game 4 of the second round of the NBA Playoffs. The Knicks are favored by 1.5 points in the matchup, which airs on ABC at 3:30 p.m. ET. The point total is 212.5 in the matchup.

76ers vs. Knicks Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

76ers vs. Knicks Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Knicks win (60.8%)

76ers vs. Knicks Betting Trends

• The Knicks have covered the spread 42 times this season (42-39-1).
• The 76ers are 40-40-2 against the spread this season.
• Games involving the Knicks have hit the over 37 times this season.
• The 76ers have gone over the point total 50% of the time this season (41 of 82 games with a set point total).
• New York has done a better job covering the spread when playing at home (27-13-0) than it has in road games (15-26-1).
• The Knicks have gone over the total more consistently at home, hitting the over in 19 of 40 home matchups (47.5%). On the road, they have hit the over in 18 of 42 games (42.9%).
• In 2025-26 against the spread, Philadelphia has a lower winning percentage at home (.439, 18-22-1 record) than away (.537, 22-18-1).
• Looking at the over/under, 76ers games have gone over less often at home (20 of 41, 48.8%) than away (21 of 41, 51.2%).

Knicks Leaders

• Jalen Brunson averages 26 points, 3.3 rebounds and 6.8 assists, shooting 46.7% from the field and 36.9% from beyond the arc, with 2.6 made treys per game.
• Karl-Anthony Towns is averaging 20.1 points, 3 assists and 11.9 boards.
• Mikal Bridges' numbers on the season are 14.4 points, 3.8 rebounds and 3.7 assists per game, shooting 49% from the field and 37.1% from downtown, with an average of 1.9 made treys.
• OG Anunoby is averaging 16.7 points, 5.2 rebounds and 2.2 assists.
• Josh Hart is averaging 12 points, 7.4 boards and 4.8 assists.

76ers Leaders

• Tyrese Maxey's numbers on the season are 28.3 points, 4.1 boards and 6.6 assists per game. He is also sinking 46.2% of his shots from the field and 36.7% from 3-point range, with an average of 3.1 triples (ninth in NBA).
• VJ Edgecombe averages 16 points, 5.6 boards and 4.2 assists. He is also draining 43.8% of his shots from the floor and 35.4% from 3-point range, with 2 triples per contest.
• The 76ers get 13.4 points per game from Quentin Grimes, plus 3.6 boards and 3.3 assists.
• Joel Embiid's numbers on the season are 26.9 points, 7.7 boards and 3.9 assists per game. He is draining 48.9% of his shots from the floor and 33.3% from 3-point range, with an average of 1.4 treys.
• The 76ers receive 6.4 points per game from Andre Drummond, plus 8.4 boards and 1.3 assists.

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