49ers vs Browns Prediction, Odds, Moneyline, Betting Trends, Spread & Over/Under for NFL Week 6 - October 15

In NFL action on Sunday, the San Francisco 49ers play the Cleveland Browns.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding today's NFL betting odds.

49ers vs Browns Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: 49ers win (70.2%)

49ers vs Browns Point Spread

The 49ers are 9.5-point favorites against the Browns. The 49ers are -110 to cover the spread, while the Browns are -110 to cover as a 9.5-point underdog.

49ers vs Browns Over/Under

An over/under of 35.5 has been set for 49ers-Browns on October 15, with the over being -115 and the under -105.

49ers vs Browns Moneyline

The moneyline numbers for 49ers vs. Browns reveal San Francisco as the favorite (-460) and Cleveland as the underdog (+360) despite being the home team.

49ers vs Browns Betting Trends

• San Francisco has beaten the spread four times in five games.
• The 49ers are unbeaten ATS (2-0) as a 9.5-point favorite or greater this year.
• The 49ers have played five games this year and three of them have gone over the total.
• The Browns have posted two wins against the spread this season.
• The Browns have had one game (out of four) hit the over this season.

49ers vs Browns Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-460) | CLE: (+360)
• Spread: SF: -9.5 (-110) | CLE: +9.5 (-110)
• Total: 35.5 -- Over: (-115) | Under: (-105)

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