Yankees vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for March 27

Odds updated as of 4:11 p.m.

Friday's slate in the MLB includes a matchup between the New York Yankees and the San Francisco Giants.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Yankees vs Giants Game Info

• New York Yankees (1-0) vs. San Francisco Giants (0-1)
• Date: Friday, March 27, 2026
• Time: 4:35 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and YES

Yankees vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-134) | SF: (+114)
• Spread: NYY: -1.5 (+122) | SF: +1.5 (-146)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Yankees vs Giants Probable Starting Pitchers

Probable Pitchers: Cam Schlittler (Yankees) - 0-0, 0.00 ERA vs Robbie Ray (Giants) - 0-0, 0.00 ERA

The Yankees will give the nod to Cam Schlittler versus the Giants and Robbie Ray. In 16 games he pitched with a spread last season, Schlittler and his team finished with a 9-7-0 record ATS. Schlittler and his team were 8-5 when he pitched and they were the moneyline favorite. Last season Ray and his team had a 20-12-0 record against the spread in games he pitched. Ray and his team went 7-4 in games he pitched when they were the moneyline underdog a season ago.

Yankees vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (53%)

Yankees vs Giants Moneyline

• The moneyline numbers for Yankees vs. Giants reveal New York as the favorite (-134) and San Francisco as the underdog (+114) despite being the home team.

Yankees vs Giants Spread

• The Giants are at +1.5 on the runline against the Yankees. The Giants are -146 to cover the spread, and the Yankees are +122.

Yankees vs Giants Over/Under

• A combined run total of 8.5 has been set for Yankees-Giants on March 27, with the over at -105 and the under at -115.

Bet on New York Yankees vs. San Francisco Giants on FanDuel today!

Yankees vs Giants Betting Trends

• The Yankees were chosen as favorites in 143 games last year and walked away with the win 88 times (61.5%) in those games.
• Last season New York came away with a win 74 times in 115 chances when named as a favorite of at least -134 or shorter on the moneyline.
• The Yankees and their opponents hit the over in 79 of their 166 games with a total last season.
• The Giants finished 29-36 in games they were the underdog on the moneyline last season (winning 44.6% of those games).
• When playing as a moneyline underdog with odds of +114 or longer last year, San Francisco went 16-21 (43.2%).
• The Giants played in 161 games with an over/under set last season, and combined with their opponents to go over the total 77 times (77-76-8).

Yankees Player Leaders

• Aaron Judge had 179 base hits and an OBP of .457 to go with a slugging percentage of .688 last season.
• Cody Bellinger slashed .272/.334/.480 and finished with an OPS of .813.
• Trent Grisham ended his last campaign with 116 hits, an OBP of .348, plus a slugging percentage of .465.
• Ben Rice slashed .255/.337/.499 and finished with an OPS of .836.

Giants Player Leaders

• Rafael Devers put up an OBP of .372 with 153 hits last season.
• Luis Arraez slugged .392 while batting .292.
• Willy Adames hit .225 with 22 doubles, two triples, 30 home runs and 80 walks a season ago.
• Jung Hoo Lee hit .266 with 31 doubles, 12 triples, eight home runs and 47 walks.

Yankees vs Giants Head to Head

• 3/25/2026: 7-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/13/2025: 5-4 SF (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/12/2025: 8-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/11/2025: 9-1 SF (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 6/2/2024: 7-5 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/1/2024: 7-3 NYY (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/31/2024: 6-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/2/2023: 6-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/1/2023: 7-5 SF (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 3/30/2023: 5-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 6.5, Favorite Moneyline: -178, Underdog Moneyline: +150)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!