The No. 6 seed Villanova Wildcats (17-14, 10-10 Big East) square off against the No. 11 seed DePaul Blue Demons (3-28, 0-20 Big East) in the Big East tournament Wednesday at Madison Square Garden, beginning at 9:00 PM ET. Both teams will look to take one step closer to securing an automatic place in the NCAA Tournament.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Villanova vs. DePaul Game Info and Odds

• Game Day: Wednesday, March 13, 2024
• Game Time: 9:00 PM ET
• TV Channel: Fox Sports 1
• Location: New York City, New York
• Arena: Madison Square Garden

Villanova vs. DePaul Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Villanova win (97%)

See the betting trends and insights below before placing a bet on Wednesday's Villanova-DePaul spread (Villanova -24.5) or over/under (136.5 points).

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Villanova vs. DePaul: ATS Betting Stats and Trends

• Villanova is 17-14-0 ATS this season.
• DePaul has covered 12 times in 31 matchups with a spread this season.
• Villanova hasn't covered the spread as a 24.5-point favorite or more this season, while DePaul covers as an underdog of 24.5 or more 50% of the time.
• The Wildcats have done a better job covering the spread in home games (9-6-0) than they have in road tilts (5-7-0).
• The Blue Demons have been better against the spread away (5-6-0) than at home (6-12-0) this year.
• Villanova is 11-9-0 against the spread in conference games this year.
• DePaul has beaten the spread seven times in 20 Big East games.

Villanova vs. DePaul: Moneyline Betting Stats

• Villanova has been the moneyline favorite in 18 games this season and has come away with the win 12 times (66.7%) in those contests.
• This is the best odds of a victory sportsbooks have given the Wildcats this season with a -10000 moneyline set for this game.
• DePaul has lost all 24 of the games it has been listed as the moneyline underdog this season.
• The Blue Demons have played as a moneyline underdog of +2500 or longer in just two games this season, which they lost both.
• Oddsmakers have implied with the moneyline set for this matchup that Villanova has a 99% chance of pulling out a win.

Villanova vs. DePaul Head-to-Head Comparison

• Villanova averages 71.1 points per game (254th in college basketball) while allowing 65.6 per contest (21st in college basketball). It has a +171 scoring differential overall and outscores opponents by 5.5 points per game.
• Eric Dixon ranks 172nd in the nation with a team-leading 16.3 points per game.
• DePaul has been outscored by 17.5 points per game (posting 65.0 points per game, 347th in college basketball, while allowing 82.5 per contest, 360th in college basketball) and has a -544 scoring differential.
• Chico Carter Jr.'s 11.3 points per game leads DePaul and ranks 824th in the country.
• The Wildcats pull down 34.7 rebounds per game (214th in college basketball) compared to the 33.8 of their opponents.
• Tyler Burton leads the Wildcats with 6.3 rebounds per game (277th in college basketball play).
• The Blue Demons lose the rebound battle by 7.1 boards on average. They collect 29.5 rebounds per game, 357th in college basketball, while their opponents pull down 36.6.
• Elijah Fisher tops the Blue Demons with 3.7 rebounds per game (1230th in college basketball).
• Villanova ranks 108th in college basketball with 98.0 points scored per 100 possessions, and 102nd in college basketball defensively with 90.4 points conceded per 100 possessions.
• The Blue Demons rank 342nd in college basketball with 85.8 points scored per 100 possessions, and 363rd defensively with 109.0 points conceded per 100 possessions.

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