Twins vs Tigers Prediction, Odds, Moneyline, Spread & Over/Under for April 6

Odds updated as of 7:12 p.m.

The Monday slate in MLB includes a matchup between the Minnesota Twins and the Detroit Tigers.

We've got you covered, in terms of the most important information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Twins vs Tigers Game Info

• Minnesota Twins (3-6) vs. Detroit Tigers (4-5)
• Date: Monday, April 6, 2026
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: Twins.TV and DSN

Twins vs Tigers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-122) | DET: (+104)
• Spread: MIN: -1.5 (+180) | DET: +1.5 (-220)
• Total: 7 -- Over: (-115) | Under: (-105)

Twins vs Tigers Probable Starting Pitchers

Probable Pitchers: Joe Ryan (Twins) - 0-1, 4.82 ERA vs Casey Mize (Tigers) - 0-0, 1.50 ERA

The Twins will give the nod to Joe Ryan (0-1, 4.82 ERA), who is eyeing win No. 1 on the season, and the Tigers will counter with Casey Mize. Ryan has a record of 1-1-0 ATS in two starts with a spread this season. Ryan's team lost his only start as a favorite this season. Mize has started just one game with a set spread, which the Tigers failed to cover. The Tigers have not been a moneyline underdog when Mize starts this season.

Twins vs Tigers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (52.3%)

Twins vs Tigers Moneyline

• Detroit is the underdog, +104 on the moneyline, while Minnesota is a -122 favorite at home.

Twins vs Tigers Spread

• The Twins are 1.5-run home favorites on the runline against the Tigers. The Twins are +180 to cover, and the Tigers are -220.

Twins vs Tigers Over/Under

• The Twins-Tigers game on April 6 has been given an over/under of 7 runs. The over is set at -115 and the under at -105.

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Twins vs Tigers Betting Trends

• The Twins have been chosen as favorites in three games this year and have walked away with the win one time (33.3%) in those games.
• Minnesota has not played a game this season with better moneyline odds than -122.
• The Twins and their opponents have gone over in four of their nine games with a total set by sportsbooks this season.
• In nine games with a line this season, the Twins have a mark of 4-5-0 against the spread.
• The Tigers have been listed as the moneyline underdog just two other times so far this season, and they split the games.
• Detroit has played as a moneyline underdog of +104 or longer in only one game this season, which it won.
• The Tigers have played in nine games with a set over/under, and have combined with their opponents to go over the total four times (4-4-1).
• The Tigers are 4-5-0 against the spread this season.

Twins Player Leaders

• Josh Bell leads Minnesota in OBP (.371) and total hits (six) this season. He's batting .222 batting average while slugging .556.
• Among qualified hitters in baseball, he is 111th in batting average, 50th in on-base percentage, and 29th in slugging.
• Royce Lewis has two doubles, two home runs and four walks. He's batting .167 and slugging .500 with an on-base percentage of .310.
• Among qualifying batters, he is 163rd in batting average, 106th in on-base percentage and 45th in slugging percentage.
• Tristan Gray has collected four base hits, an OBP of .353 and a slugging percentage of .571 this season.
• Trevor Larnach has no home runs, but two RBI and a batting average of .273 this season.

Tigers Player Leaders

• Kevin McGonigle has three doubles, a triple and six walks while batting .303. He's slugging .455 with an on-base percentage of .410.
• He ranks 36th in batting average, 27th in on-base percentage and 63rd in slugging percentage among all qualified hitters in the big leagues.
• Dillon Dingler has a double, two home runs and three walks while batting .240. He's slugging .520 with an on-base percentage of .367.
• Including all qualifying hitters, he ranks 88th in batting average, 55th in on-base percentage and 40th in slugging percentage.
• Gleyber Torres is batting .219 with a home run and nine walks.
• Riley Greene is batting .229 with three doubles and four walks.

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