San Diego State vs Northern Illinois Prediction, Odds, Picks, Best Bets for Week 5 2025

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NCAA football action on Saturday includes the San Diego State Aztecs taking on the Northern Illinois Huskies.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

San Diego State vs Northern Illinois Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: San Diego State: (-120) | Northern Illinois: (+100)
Spread: San Diego State: -1.5 (-110) | Northern Illinois: +1.5 (-110)
Total: 42.5 -- Over: (-114) | Under: (-106)

San Diego State has won twice against the spread this season.
San Diego State has yet to lose ATS (1-0) as a 1.5-point favorite or greater this season.
San Diego State has had one game (of three) go over the total this year.
Northern Illinois has but one win versus the spread this year.
Northern Illinois has won once ATS (1-1) as a 1.5-point underdog or greater this year.
None of Northern Illinois' three games has gone over the point total in 2025.

All college football win probability predictions and picks are according to numberFire.
Prediction: Huskies win (55.8%)

San Diego State is favored by 1.5 points against Northern Illinois. San Diego State is -110 to cover the spread, while Northern Illinois is -110.

An over/under of 42.5 has been set for San Diego State-Northern Illinois on Sept. 27, with the over being -114 and the under -106.

Northern Illinois is the underdog, +100 on the moneyline, while San Diego State is a -120 favorite.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
San Diego State	29.7	96	12.0	8	49.5	3
Northern Illinois	12.7	136	25.0	49	47.5	3

Check out even more in-depth San Diego State vs. Northern Illinois analysis on FanDuel Research.

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