Red Sox vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for March 28

Odds updated as of 3:21 p.m.

The MLB's Saturday schedule includes the Boston Red Sox facing the Cincinnati Reds.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Red Sox vs Reds Game Info

• Boston Red Sox (1-0) vs. Cincinnati Reds (0-1)
• Date: Saturday, March 28, 2026
• Time: 4:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and NESN

Red Sox vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-134) | CIN: (+114)
• Spread: BOS: -1.5 (+120) | CIN: +1.5 (-144)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Red Sox vs Reds Probable Starting Pitchers

Probable Pitchers: Sonny Gray (Red Sox) - 0-0, 0.00 ERA vs Brady Singer (Reds) - 0-0, 0.00 ERA

The Red Sox will call on Sonny Gray against the Reds and Brady Singer. In games Gray pitched with a spread last season, his team was 17-15-0 ATS. Gray and his team had a 14-7 record when he pitched as a favorite last season. Last season Singer and his team had a 17-14-0 record against the spread in games he pitched. Singer and his team had a 11-6 record in games he pitched when they were the moneyline underdog a season ago.

Red Sox vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (52%)

Red Sox vs Reds Moneyline

• The moneyline numbers for Red Sox vs. Reds reveal Boston as the favorite (-134) and Cincinnati as the underdog (+114) despite being the home team.

Red Sox vs Reds Spread

• The Red Sox are favored by 1.5 runs on the road versus the Reds. The Red Sox are +120 to cover the spread, while the Reds are -144.

Red Sox vs Reds Over/Under

• A combined run total of 7.5 has been set for Red Sox-Reds on March 28, with the over at -115 and the under at -105.

Bet on Boston Red Sox vs. Cincinnati Reds on FanDuel today!

Red Sox vs Reds Betting Trends

• The Red Sox came away with 58 wins in the 101 contests they were listed as the favorites last season.
• Last year, Boston won 30 of 52 games when listed as at least -134 on the moneyline.
• The Red Sox and their opponents hit the over in 74 of their 164 games with a total last season.
• The Reds won 42 of the 87 games they were the moneyline underdog last season (48.3%).
• Cincinnati went 19-29 when playing as a moneyline underdog with odds of +114 or longer (39.6%).
• The Reds combined with their opponents to hit the over on the total 61 times last season for a 61-84-10 record against the over/under.

Red Sox Player Leaders

• Last season, Jarren Duran finished with 16 home runs, 84 RBI and a batting average of .256 last season.
• Trevor Story hit 25 homers while driving in 96 runs.
• Ceddanne Rafaela ended his last campaign with 136 hits, an OBP of .295, plus a slugging percentage of .414.
• Caleb Durbin slashed .256/.334/.387 and finished with an OPS of .721.

Reds Player Leaders

• Elly De La Cruz racked up a slugging percentage of .440 and a batting average of .264 last season.
• Eugenio Suarez collected 134 hits while batting .228.
• TJ Friedl put up a .364 on-base percentage last season while batting .261.
• Spencer Steer hit .238 with 21 doubles, two triples, 21 home runs and 51 walks.

Red Sox vs Reds Head to Head

• 3/26/2026: 3-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/2/2025: 8-4 CIN (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/30/2025: 13-6 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/23/2024: 7-4 BOS (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/22/2024: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/21/2024: 5-2 CIN (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/1/2023: 8-2 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/31/2023: 5-4 CIN (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 5/30/2023: 9-8 CIN (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/21/2022: 5-1 CIN (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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