Red Sox vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for March 26

Odds updated as of 4:12 p.m.

The Boston Red Sox and the Cincinnati Reds meet for MLB Opening Day on Thursday.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Red Sox vs Reds Game Info

• Boston Red Sox (0-0) vs. Cincinnati Reds (0-0)
• Date: Thursday, March 26, 2026
• Time: 4:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and NESN

Red Sox vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-158) | CIN: (+134)
• Spread: BOS: -1.5 (+110) | CIN: +1.5 (-132)
• Total: 8 -- Over: (-108) | Under: (-112)

Red Sox vs Reds Probable Starting Pitchers

Probable Pitchers: Garrett Crochet (Red Sox) - 0-0, 0.00 ERA vs Andrew Abbott (Reds) - 0-0, 0.00 ERA

The Red Sox will look to Garrett Crochet versus the Reds and Andrew Abbott. In 33 games he pitched with a spread last season, Crochet and his team finished with a 20-13-0 record ATS. Crochet and his team won 70% of the games he started as the moneyline favorite last season, with a record of 21-9. Last season when Abbott pitched his team finished 16-13-0 against the spread. Abbott and his team went 8-4 in games he appeared in when they were moneyline underdogs a season ago.

Red Sox vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (52.4%)

Red Sox vs Reds Moneyline

• Looking at the moneyline for Red Sox-Reds, Boston is the favorite at -158, and Cincinnati is +134 playing at home.

Red Sox vs Reds Spread

• The Red Sox are at the Reds and are favored by 1.5 runs (+110 to cover) on the runline. Cincinnati is -132 to cover.

Red Sox vs Reds Over/Under

• The Red Sox-Reds game on March 26 has been given an over/under of 8 runs. The over is set at -108 and the under at -112.

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Red Sox vs Reds Betting Trends

• The Red Sox were chosen as favorites in 101 games last year and walked away with the win 58 times (57.4%) in those games.
• Last season Boston came away with a win 20 times in 32 chances when named as a favorite of at least -158 or shorter on the moneyline.
• The Red Sox and their opponents hit the over in 74 of their 164 games with a total last season.
• The Reds went 42-45 in games they were listed as the moneyline underdog last season (winning 48.3% of those games).
• Cincinnati went 12-14 in games it played as a moneyline underdog with odds of +134 or longer (46.2%).
• The Reds played in 155 games with a set over/under last season, and combined with their opponents to go over the total 61 times (61-84-10).

Red Sox Player Leaders

• Jarren Duran ended his last campaign with 159 hits, an OBP of .332 plus a slugging percentage of .442.
• Trevor Story had an OPS of .741, fueled by an OBP of .308 and a slugging percentage of .433.
• Ceddanne Rafaela ended his last campaign with 136 hits, an OBP of .295, plus a slugging percentage of .414.
• Caleb Durbin slashed .256/.334/.387 and finished with an OPS of .721.

Reds Player Leaders

• Elly De La Cruz put up a .440 slugging percentage and a .264 batting average last year.
• Eugenio Suarez collected 134 hits while batting .228.
• TJ Friedl had a .364 on-base percentage while batting .261 last season.
• Spencer Steer hit .238 with 21 doubles, two triples, 21 home runs and 51 walks.

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