Red Sox vs Mets Prediction, Odds, Moneyline, Spread & Over/Under for May 21

Odds updated as of 6:11 p.m.

The MLB schedule on Wednesday includes the Boston Red Sox facing the New York Mets.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Red Sox vs Mets Game Info

• Boston Red Sox (25-25) vs. New York Mets (29-20)
• Date: Wednesday, May 21, 2025
• Time: 6:45 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: MLB Network, NESN, and SNY

Red Sox vs Mets Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-152) | NYM: (+128)
• Spread: BOS: -1.5 (+142) | NYM: +1.5 (-172)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Red Sox vs Mets Probable Starting Pitchers

Probable Pitchers: Garrett Crochet (Red Sox) - 4-3, 2.00 ERA vs Tylor Megill (Mets) - 3-4, 3.74 ERA

The Red Sox will give the nod to Garrett Crochet (4-3) against the Mets and Tylor Megill (3-4). Crochet's team is 5-5-0 against the spread in his starts this season. Crochet's team is 5-4 this season when he starts and they are the moneyline favorite. The Mets are 2-7-0 against the spread when Megill starts. The Mets were the moneyline underdog for two Megill starts this season -- they split the games.

Red Sox vs Mets Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (51.9%)

Red Sox vs Mets Moneyline

• New York is the underdog, +128 on the moneyline, while Boston is a -152 favorite at home.

Red Sox vs Mets Spread

• The Mets are +1.5 on the run line against the Red Sox. The Mets are -172 to cover, and the Red Sox are +142.

Red Sox vs Mets Over/Under

• The over/under for the Red Sox versus Mets contest on May 21 has been set at 7.5, with -110 odds on the over and -110 odds on the under.

Bet on Boston Red Sox vs. New York Mets on FanDuel today!

Red Sox vs Mets Betting Trends

• The Red Sox have come away with 18 wins in the 35 contests they have been listed as the favorites in this season.
• This season Boston has been victorious five times in 11 chances when named as a favorite of at least -152 on the moneyline.
• The Red Sox and their opponents have gone over in 24 of their 50 games with a total set by sportsbooks this season.
• The Red Sox have posted a record of 26-24-0 against the spread this season.
• The Mets have been the underdog on the moneyline 13 total times this season. They've finished 6-7 in those games.
• New York has played as a moneyline underdog of +128 or longer in only one game this season, which it lost.
• The Mets have played in 48 games with an over/under set, and have combined with their opponents to go over the total 17 times (17-29-2).
• The Mets have put together a 22-26-0 record ATS this season (covering 45.8% of the time).

Red Sox Player Leaders

• Alex Bregman leads Boston in slugging percentage (.565) and total hits (58) this season. He's batting .304 with an on-base percentage of .388.
• Among qualifying hitters in baseball, his batting average ranks 18th, his on-base percentage ranks 16th, and he is eighth in slugging.
• Bregman hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .188 with two doubles, three walks and two RBIs.
• Rafael Devers leads Boston in OBP (.407) this season, fueled by 53 hits. He's batting .286 while slugging .524.
• He ranks 35th in batting average, fifth in on-base percentage and 19th in slugging among qualifying batters.
• Wilyer Abreu is batting .264 with a .515 slugging percentage and 27 RBI this year.
• Abreu has picked up a hit in two straight games. In his last five games he is hitting .125 with a double.
• Jarren Duran is batting .264 with a .314 OBP and 28 RBI for Boston this season.

Mets Player Leaders

• Pete Alonso has put up a team-high OBP (.400), and leads the Mets in hits (53). He's batting .294 and slugging.
• Including all the qualifying players in the big leagues, his batting average is 25th, his on-base percentage ranks ninth, and he is 14th in slugging.
• Juan Soto is hitting .247 with nine doubles, eight home runs and 38 walks. He's slugging .437 with an on-base percentage of .379.
• He is 95th in batting average, 23rd in on-base percentage and 69th in slugging percentage in MLB.
• Francisco Lindor has a slugging percentage of .461, a team-best for the Mets.
• Brandon Nimmo has nine doubles, eight home runs and 15 walks while batting .215.

Red Sox vs Mets Head to Head

• 5/20/2025: 2-0 BOS (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/19/2025: 3-1 BOS (Favorite: Mets, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/4/2024: 8-3 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/3/2024: 7-2 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/2/2024: 4-1 NYM (Favorite: Mets, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/23/2023: 6-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/22/2023: 8-6 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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