Athletics vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 21

Odds updated as of 9:11 p.m.

The Athletics are among the MLB teams busy on Wednesday, up against the Los Angeles Angels.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Athletics vs Angels Game Info

• Athletics (22-27) vs. Los Angeles Angels (22-25)
• Date: Wednesday, May 21, 2025
• Time: 10:05 p.m. ET
• Venue: Sutter Health Park -- West Sacramento, California
• Coverage: NBCS-CA and FDSW

Athletics vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: OAK: (-162) | LAA: (+136)
• Spread: OAK: -1.5 (+122) | LAA: +1.5 (-146)
• Total: 10.5 -- Over: (-104) | Under: (-118)

Athletics vs Angels Probable Starting Pitchers

Probable Pitchers: JP Sears (Athletics) - 4-3, 3.31 ERA vs Jack Kochanowicz (Angels) - 3-5, 4.71 ERA

The Athletics will give the nod to JP Sears (4-3, 3.31 ERA), who is eyeing win No. 5 on the season, and the Angels will turn to Jack Kochanowicz (3-5, 4.71 ERA). When Sears starts, his team is 6-3-0 against the spread this season. Sears' team has won each of the three games he's started as the moneyline favorite. The Angels are 3-6-0 ATS in Kochanowicz's nine starts that had a set spread. The Angels have a 3-4 record in Kochanowicz's seven starts this season when they were the moneyline underdog.

Athletics vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (60.1%)

Athletics vs Angels Moneyline

• The Athletics vs Angels moneyline has the Athletics as a -162 favorite, while the Angels are a +136 underdog on the road.

Athletics vs Angels Spread

• The Athletics are 1.5-run favorites on the runline against the Angels. The Athletics are +122 to cover, while the Angels are -146 to cover.

Athletics vs Angels Over/Under

• The over/under for the Athletics versus Angels game on May 21 has been set at 10.5, with -104 odds on the over and -118 odds on the under.

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Athletics vs Angels Betting Trends

• The Athletics have been favorites in 16 games this season and have come away with the win nine times (56.2%) in those contests.
• This season, the Athletics have come away with a win three times in five chances when named as a favorite of at least -162 or shorter on the moneyline.
• The Athletics and their opponents have hit the over in 26 of their 49 games with a total this season.
• The Athletics are 24-25-0 against the spread in their 49 games that had a posted line this season.
• The Angels have won 18 of the 39 games they were the underdog on the moneyline this season (46.2%).
• When they have played as a moneyline underdog with odds of +136 or longer, the Angels have a record of 8-8 (50%).
• The Angels have combined with their opponents to go over the total 26 times this season for a 26-20-1 record against the over/under.
• The Angels have covered 44.7% of their games this season, going 21-26-0 ATS.

Athletics Player Leaders

• Jacob Wilson leads Sacramento with an OBP of .381, plus a team-best slugging percentage of .478. He's batting .341 on the season.
• Among qualified hitters in MLB, his batting average ranks third, his on-base percentage ranks 18th, and he is 42nd in slugging.
• Tyler Soderstrom leads Sacramento with 51 hits. He is batting .270 this season and has 20 extra-base hits. He's also slugging .481 with an on-base percentage of .329.
• He is 60th in batting average, 82nd in on-base percentage and 40th in slugging among qualifying hitters.
• Soderstrom enters this game looking to extend his two-game hit streak. In his last five games he is hitting .190 with two doubles and an RBI.
• Shea Langeliers has 41 hits this season and has a slash line of .256/.320/.463.
• Langeliers brings a two-game hitting streak into this game. During his last five outings he is hitting .176 with a home run, two walks and two RBIs.
• Brent Rooker has been key for Sacramento with 47 hits, an OBP of .308 plus a slugging percentage of .441.
• Rooker has safely hit in two straight games. In his last five games he is hitting .167 with three walks and an RBI.

Angels Player Leaders

• Nolan Schanuel has a .366 on-base percentage and a .403 slugging percentage, both team-high numbers for the Angels. He's batting .277.
• Including all the qualified hitters in the majors, he is 50th in batting average, 37th in on-base percentage and 93rd in slugging percentage.
• Schanuel enters this game on a five-game hitting streak. In his last five games he is hitting .400 with three doubles, a home run, four walks and four RBIs.
• Taylor Ward is hitting .203 with nine doubles, 13 home runs and 12 walks. He's slugging .467 with an on-base percentage of .250.
• Including all qualifying hitters, he ranks 151st in batting average, 160th in on-base percentage and 45th in slugging percentage.
• Zach Neto has nine doubles, seven home runs and seven walks while hitting .278.
• Logan O'Hoppe leads his team with 38 hits.

Athletics vs Angels Head to Head

• 5/20/2025: 7-5 LAA (Favorite: Athletics, Spread: -1.5, Total: 10.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/19/2025: 4-3 LAA (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/28/2024: 8-6 LAA (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/27/2024: 3-1 OAK (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/26/2024: 5-4 OAK (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/25/2024: 6-5 OAK (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/21/2024: 8-5 LAA (Favorite: Athletics, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/20/2024: 8-2 OAK (Favorite: Athletics, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 7/19/2024: 13-3 OAK (Favorite: Athletics, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/4/2024: 5-0 OAK (Favorite: Athletics, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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