Athletics vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for May 21

Odds updated as of 10:11 a.m.

The Athletics will face the Los Angeles Angels in MLB action on Wednesday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Athletics vs Angels Game Info

• Athletics (22-27) vs. Los Angeles Angels (22-25)
• Date: Wednesday, May 21, 2025
• Time: 10:05 p.m. ET
• Venue: Sutter Health Park -- West Sacramento, California
• Coverage: NBCS-CA and FDSW

Athletics vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: OAK: (-166) | LAA: (+140)
• Spread: OAK: -1.5 (+106) | LAA: +1.5 (-128)
• Total: 10.5 -- Over: (-118) | Under: (-104)

Athletics vs Angels Probable Starting Pitchers

Probable Pitchers: JP Sears (Athletics) - 4-3, 3.31 ERA vs Jack Kochanowicz (Angels) - 3-5, 4.71 ERA

The Athletics will give the ball to JP Sears (4-3, 3.31 ERA), who is eyeing win No. 5 on the season, and the Angels will turn to Jack Kochanowicz (3-5, 4.71 ERA). Sears' team is 6-3-0 against the spread in his starts this season. Sears and his team have won each of the three games he's started as the moneyline favorite. The Angels are 3-6-0 ATS in Kochanowicz's nine starts with a set spread. The Angels have a 3-4 record in Kochanowicz's seven starts this season when they were the moneyline underdog.

Athletics vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (60.1%)

Athletics vs Angels Moneyline

• The Athletics vs Angels moneyline has the Athletics as a -166 favorite, while the Angels are a +140 underdog on the road.

Athletics vs Angels Spread

• The Athletics are 1.5-run favorites on the runline against the Angels. The Athletics are +106 to cover, while the Angels are -128 to cover.

Athletics vs Angels Over/Under

• A total of 10.5 runs has been set for the Athletics-Angels game on May 21, with the over available at -118 and the under at -104.

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Athletics vs Angels Betting Trends

• The Athletics have come away with nine wins in the 16 contests they have been listed as the favorites in this season.
• This season, the Athletics have come away with a win two times in four chances when named as a favorite of at least -166 or shorter on the moneyline.
• The Athletics and their opponents have hit the over in 26 of their 49 games with a total this season.
• In 49 games with a line this season, the Athletics have a mark of 24-25-0 against the spread.
• The Angels have put together an 18-21 record in games they were the underdog on the moneyline (winning 46.2% of those games).
• The Angels have a record of 7-7 when playing as a moneyline underdog with odds of +140 or longer (50%).
• The Angels have combined with their opponents to hit the over on the total 26 times this season for a 26-20-1 record against the over/under.
• The Angels have collected a 21-26-0 record against the spread this season (covering 44.7% of the time).

Athletics Player Leaders

• Jacob Wilson leads Sacramento OPS (.859) this season. He has a .341 batting average, an on-base percentage of .381, and a slugging percentage of .478.
• Among qualifying hitters, he ranks third in batting average, his on-base percentage ranks 19th, and he is 41st in slugging.
• Tyler Soderstrom leads Sacramento in total hits (51) this season while batting .270 with 20 extra-base hits. He's slugging .481 with an on-base percentage of .329.
• Among qualifying hitters, his batting average places him 61st, his on-base percentage 83rd, and his slugging percentage 40th.
• Soderstrom heads into this game looking to extend his two-game hit streak. In his last five games he is batting .190 with two doubles and an RBI.
• Shea Langeliers is batting .256 with a .463 slugging percentage and 25 RBI this year.
• Langeliers brings a two-game hitting streak into this matchup. During his last five outings he is batting .176 with a home run, two walks and two RBIs.
• Brent Rooker is batting .241 with a .308 OBP and 23 RBI for Sacramento this season.
• Rooker has safely hit in two games in a row. During his last five outings he is hitting .167 with three walks and an RBI.

Angels Player Leaders

• Nolan Schanuel has a team-high OBP (.366) and slugging percentage (.403). He's batting .277.
• Including all the qualifying hitters in the big leagues, he ranks 52nd in batting average, 39th in on-base percentage and 94th in slugging percentage.
• Schanuel brings a five-game hitting streak into this matchup. In his last five games he is batting .400 with three doubles, a home run, four walks and four RBIs.
• Taylor Ward is batting .203 with nine doubles, 13 home runs and 12 walks. He's slugging .467 with an on-base percentage of .250.
• He is currently 152nd in batting average, 160th in on-base percentage and 44th in slugging percentage among all qualified hitters.
• Zach Neto is batting .278 with nine doubles, seven home runs and seven walks.
• Logan O'Hoppe has racked up 38 hits to lead his team.

Athletics vs Angels Head to Head

• 5/20/2025: 7-5 LAA (Favorite: Athletics, Spread: -1.5, Total: 10.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/19/2025: 4-3 LAA (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/28/2024: 8-6 LAA (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/27/2024: 3-1 OAK (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/26/2024: 5-4 OAK (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/25/2024: 6-5 OAK (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/21/2024: 8-5 LAA (Favorite: Athletics, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/20/2024: 8-2 OAK (Favorite: Athletics, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 7/19/2024: 13-3 OAK (Favorite: Athletics, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/4/2024: 5-0 OAK (Favorite: Athletics, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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