Red Sox vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 6:12 p.m.

The MLB slate on Wednesday includes the Boston Red Sox facing the Seattle Mariners.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Red Sox vs Mariners Game Info

• Boston Red Sox (14-11) vs. Seattle Mariners (12-11)
• Date: Wednesday, April 23, 2025
• Time: 6:45 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: NESN and ROOT Sports NW

Red Sox vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-136) | SEA: (+116)
• Spread: BOS: -1.5 (+142) | SEA: +1.5 (-172)
• Total: 9.5 -- Over: (-110) | Under: (-110)

Red Sox vs Mariners Probable Starting Pitchers

Probable Pitchers: Sean Newcomb (Red Sox) - 0-2, 3.63 ERA vs Emerson Hancock (Mariners) - 0-1, 12.71 ERA

This contest's pitching matchup is set, as the Red Sox will send Sean Newcomb (0-2) to the mound, while Emerson Hancock (0-1) will take the ball for the Mariners. Newcomb's team is 2-2-0 against the spread this season in his starts. Newcomb's team is 1-1 this season when he starts and they're favored on the moneyline. Hancock has started two games with set spreads, and the Mariners went 1-1-0. The Mariners were the moneyline underdog for one Hancock start this season -- they won.

Red Sox vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (55.8%)

Red Sox vs Mariners Moneyline

• Boston is a -136 favorite on the moneyline, while Seattle is a +116 underdog on the road.

Red Sox vs Mariners Spread

• The Mariners are at +1.5 on the runline against the Red Sox. The Mariners are -172 to cover the spread, and the Red Sox are +142.

Red Sox vs Mariners Over/Under

• The over/under for the Red Sox versus Mariners game on April 23 has been set at 9.5, with -110 odds on the over and -110 odds on the under.

Bet on Boston Red Sox vs. Seattle Mariners on FanDuel today!

Red Sox vs Mariners Betting Trends

• The Red Sox have come away with 11 wins in the 18 contests they have been listed as the favorites in this season.
• Boston has a record of 4-4 when favored by -136 or more this year.
• The Red Sox and their opponents have gone over in 10 of their 25 games with a total set by sportsbooks this season.
• The Red Sox have posted a record of 13-12-0 against the spread this season.
• The Mariners have gone 4-5 in games they were the underdog on the moneyline (winning 44.4% of those games).
• Seattle has played as a moneyline underdog of +116 or longer in just two games this season, which it split 1-1.
• The Mariners have had an over/under set by bookmakers 23 times, and have combined with opponents to go over the total in 11 of those games (11-10-2).
• The Mariners have collected an 11-12-0 record against the spread this season.

Red Sox Player Leaders

• Alexander David Bregman is hitting .302 with nine doubles, four home runs and nine walks. He has an on-base percentage of .376 and a slugging percentage of .521.
• He ranks 28th in batting average, 32nd in on-base percentage, and 28th in slugging among qualified hitters in MLB.
• Bregman hopes to build on a three-game hitting streak in this matchup. During his last five outings he is batting .222 with two doubles, five walks and three RBI.
• Wilyer Abreu has 23 hits and an OBP of .419, both of which lead the Red Sox this season. He's batting .299 and slugging .532.
• His batting average is 31st among qualified players, his on-base percentage 10th, and his slugging percentage 21st.
• Trevor Story has hit five homers with a team-high .500 SLG this season.
• Kristian Campbell has three home runs, eight RBI and a batting average of .300 this season.

Mariners Player Leaders

• Cal Raleigh has accumulated a slugging percentage of .600 and has 22 hits, both team-best numbers for the Mariners. He's batting .244 and with an on-base percentage of .346.
• Including all qualified hitters, he ranks 86th in batting average, while his on-base percentage ranks 64th and he is 10th in slugging.
• Raleigh brings a six-game hitting streak into this matchup. In his last 10 games he is hitting .317 with three doubles, seven home runs, six walks and 13 RBI.
• Randy Arozarena is hitting .193 with six doubles, four home runs and 16 walks. He's slugging .410 with an on-base percentage of .350.
• He is 140th in batting average, 59th in on-base percentage and 85th in slugging percentage in the big leagues.
• Julio Rodriguez is hitting .191 with three doubles, two triples, three home runs and 13 walks.
• Dylan Moore is hitting .300 with a double, five home runs and six walks.

Red Sox vs Mariners Head to Head

• 4/22/2025: 8-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/31/2024: 3-2 BOS (Favorite: Mariners, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/30/2024: 10-6 SEA (Favorite: Mariners, Spread: -1.5, Total: 10.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/29/2024: 14-7 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 3/31/2024: 5-1 BOS (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 3/30/2024: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 3/29/2024: 1-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 3/28/2024: 6-4 BOS (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/2/2023: 6-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/1/2023: 6-4 BOS (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)

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