Phillies vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 12

Odds updated as of 2:12 p.m.

The MLB slate on Wednesday includes the Philadelphia Phillies facing the St. Louis Cardinals.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Phillies vs Cardinals Game Info

• Philadelphia Phillies (64-57) vs. St. Louis Cardinals (60-60)
• Date: Wednesday, August 12, 2026
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and NBCS-PH

Phillies vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-164) | STL: (+150)
• Spread: PHI: -1.5 (+100) | STL: +1.5 (-120)
• Total: 8 -- Over: (-104) | Under: (-118)

Phillies vs Cardinals Probable Starting Pitchers

Probable Pitchers: Zack Wheeler (Phillies) - 10-3, 2.69 ERA vs Kyle Leahy (Cardinals) - 8-4, 3.45 ERA

The Phillies will call on Zack Wheeler (10-3) against the Cardinals and Kyle Leahy (8-4). Wheeler's team is 10-6-0 against the spread in his starts this season. Wheeler's team has won 90.9% of his starts when they are favored on the moneyline (10-1). The Cardinals have gone 9-11-0 against the spread when Leahy starts. The Cardinals have a 5-8 record in Leahy's 13 starts this season when they were the underdog on the moneyline.

Phillies vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.4%)

Phillies vs Cardinals Moneyline

• Philadelphia is a -164 favorite on the moneyline, while St. Louis is a +150 underdog at home.

Phillies vs Cardinals Spread

• The Phillies are at the Cardinals and are favored by 1.5 runs (+100 to cover) on the runline. St. Louis is -120 to cover.

Phillies vs Cardinals Over/Under

• The Phillies-Cardinals game on Aug. 12 has been given an over/under of 8 runs. The over is set at -104 and the under at -118.

Bet on Philadelphia Phillies vs. St. Louis Cardinals on FanDuel today!

Phillies vs Cardinals Betting Trends

• The Phillies have been victorious in 54, or 62.8%, of the 86 contests they have been chosen as favorites in this season.
• This season Philadelphia has come away with a win 29 times in 38 chances when named as a favorite of at least -164 on the moneyline.
• The Phillies and their opponents have gone over in 53 of their 117 games with a total set by sportsbooks this season.
• The Phillies have posted a record of 45-72-0 against the spread this season.
• The Cardinals have won 46.8% of the games this season they were the underdog on the moneyline (37-42).
• St. Louis has gone 2-6 when it has played as a moneyline underdog with odds of +150 or longer (25%).
• The Cardinals have played in 116 games with a set over/under, and have combined with opponents to go over the total 46 times (46-64-6).
• The Cardinals have a 62-54-0 record ATS this season.

Phillies Player Leaders

• Bryce Harper is batting .252 with 22 doubles, three triples, 25 home runs and 82 walks. He has an on-base percentage of .370 while slugging .495.
• Among qualifying batters in the majors, he is 78th in batting average, 17th in on-base percentage, and 18th in slugging.
• Luis Arraez leads Philadelphia in slugging percentage (.432) thanks to 37 extra-base hits. He's batting .314 with an on-base percentage of .349.
• He is third in batting average, 47th in on-base percentage and 66th in slugging among qualifying batters.
• Kyle Schwarber leads his team in OBP (.374) and total hits (106) this season.
• Schwarber heads into this game with six games in a row with at least one hit. During his last 10 outings he is batting .281 with two doubles, two home runs, 11 walks and seven RBIs.
• Bryson Stott is batting .266 with a .341 OBP and 53 RBI for Philadelphia this season.
• Stott has hit safely in four games in a row. During his last five outings he is hitting .412 with a double, six walks and an RBI.

Cardinals Player Leaders

• Alec Burleson has accumulated a team-best .479 slugging percentage. He's batting .285 with an on-base percentage of .351.
• Including all qualified players, he is 18th in batting average, while his on-base percentage ranks 40th and he is 27th in slugging.
• Burleson heads into this matchup on a three-game hitting streak. In his last five games he is hitting .222 with a double, a home run, four walks and four RBIs.
• Jordan Walker's 128 hits pace his team. He has a batting average of .284 while slugging .488 with an on-base percentage of .341.
• Including all qualified hitters, he is 21st in batting average, 56th in on-base percentage and 20th in slugging percentage.
• JJ Wetherholt is hitting .244 with 12 doubles, 16 home runs and 58 walks.
• Ivan Herrera's .358 OBP paces his team.

Phillies vs Cardinals Head to Head

• 8/11/2026: 2-0 STL (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 8/10/2026: 6-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: +108)
• 5/14/2025: 14-7 STL (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/14/2025: 2-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/12/2025: 3-2 STL (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/13/2025: 7-0 STL (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/12/2025: 4-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/11/2025: 2-0 STL (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/2/2024: 5-4 STL (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/1/2024: 6-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!