Phillies vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for May 12

Odds updated as of 6:11 p.m.

The Philadelphia Phillies are among the MLB teams playing on Monday, versus the St. Louis Cardinals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this game.

Phillies vs Cardinals Game Info

• Philadelphia Phillies (24-16) vs. St. Louis Cardinals (22-19)
• Date: Monday, May 12, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: MLB Network, NBCS-PH, and FDSMW

Phillies vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-180) | STL: (+152)
• Spread: PHI: -1.5 (+118) | STL: +1.5 (-142)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Phillies vs Cardinals Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 4-1, 2.89 ERA vs Matthew Liberatore (Cardinals) - 3-3, 3.07 ERA

The probable pitchers are Cristopher Sanchez (4-1) for the Phillies and Matthew Liberatore (3-3) for the Cardinals. Sanchez and his team are 6-1-0 ATS this season when he starts. Sanchez's team is 5-1 this season when he starts and they are the moneyline favorite. The Cardinals have gone 2-5-0 ATS in Liberatore's seven starts with a set spread. The Cardinals have been the underdog on the moneyline in three of Liberatore's starts this season, and they went 2-1 in those matchups.

Phillies vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (60.5%)

Phillies vs Cardinals Moneyline

• The Phillies vs Cardinals moneyline has Philadelphia as a -180 favorite, while St. Louis is a +152 underdog on the road.

Phillies vs Cardinals Spread

• The Cardinals are +1.5 on the run line against the Phillies. The Cardinals are -142 to cover, and the Phillies are +118.

Phillies vs Cardinals Over/Under

• A total of 8.5 runs has been set for the Phillies-Cardinals contest on May 12, with the over available at -112 and the under at -108.

Bet on Philadelphia Phillies vs. St. Louis Cardinals on FanDuel today!

Phillies vs Cardinals Betting Trends

• The Phillies have won in 20, or 62.5%, of the 32 contests they have been named as odds-on favorites in this year.
• This season Philadelphia has come away with a win nine times in 10 chances when named as a favorite of at least -180 on the moneyline.
• Contests with the Phillies have gone over the total set by oddsmakers in 18 of 39 chances this season.
• In 39 games with a line this season, the Phillies have a mark of 21-18-0 against the spread.
• The Cardinals are 14-13 in games they were listed as the moneyline underdog (winning 51.9% of those games).
• St. Louis has played four times as a moneyline underdog with odds of +152 or longer, and fell in each game.
• The Cardinals have combined with opponents to go over the total 22 times this season for a 22-17-2 record against the over/under.
• The Cardinals have put together a 22-19-0 record against the spread this season (covering 53.7% of the time).

Phillies Player Leaders

• Kyle Schwarber leads Philadelphia with 39 hits and an OBP of .404 this season. He has a .269 batting average and a slugging percentage of .593.
• Among all qualifying hitters in MLB, he ranks 56th in batting average, seventh in on-base percentage, and fifth in slugging.
• Schwarber has picked up at least one hit in two games in a row. During his last five outings he is batting .333 with two home runs, a walk and four RBIs.
• Bryce Harper is batting .237 with eight doubles, seven home runs and 28 walks. He's slugging .428 with an on-base percentage of .354.
• He is 108th in batting average, 52nd in on-base percentage and 66th in slugging in the majors.
• Trea Turner has an OPS of .764, fueled by an OBP of .371 and a team-best slugging percentage of .394 this season.
• Bryson Stott has three home runs, 20 RBI and a batting average of .262 this season.

Cardinals Player Leaders

• Lars Nootbaar is hitting .244 with nine doubles, six home runs and 30 walks. He's slugging .417 with an on-base percentage of .369.
• Including all qualified hitters, he is 92nd in batting average, while his on-base percentage is 36th and he is 75th in slugging.
• Nootbaar hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .286 with two doubles, a home run, three walks and four RBIs.
• Brendan Donovan's 48 hits, .377 OBP and .457 slugging percentage all pace his team. He has a batting average of .318.
• He is currently 10th in batting average, 25th in on-base percentage and 55th in slugging percentage among all qualifying hitters.
• Nolan Arenado is batting .270 with 10 doubles, four home runs and 16 walks.
• Willson Contreras is hitting .255 with six doubles, six home runs and 15 walks.

Phillies vs Cardinals Head to Head

• 4/13/2025: 7-0 STL (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/12/2025: 4-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/11/2025: 2-0 STL (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/2/2024: 5-4 STL (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/1/2024: 6-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 5/31/2024: 4-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 4/10/2024: 4-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 4/9/2024: 3-0 STL (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 4/8/2024: 5-3 PHI (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/17/2023: 6-5 STL (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!