Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for May 26

Odds updated as of 8:16 p.m.

The MLB's Monday schedule includes the San Diego Padres taking on the Miami Marlins.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Padres vs Marlins Game Info

• San Diego Padres (29-22) vs. Miami Marlins (21-30)
• Date: Monday, May 26, 2025
• Time: 8:40 p.m. ET
• Venue: PETCO Park -- San Diego, California
• Coverage: SDPA and FDSFL

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-152) | MIA: (+128)
• Spread: SD: -1.5 (+140) | MIA: +1.5 (-170)
• Total: 8 -- Over: (-104) | Under: (-118)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Randy Vasquez (Padres) - 3-4, 3.49 ERA vs Ryan Weathers (Marlins) - 1-0, 1.80 ERA

The probable starters are Randy Vasquez (3-4) for the Padres and Ryan Weathers (1-0) for the Marlins. Vasquez's team is 5-4-0 against the spread in his starts this season. Vasquez's team is 2-0 this season when he starts and they're favored on the moneyline. Weathers has started two games with set spreads, and the Marlins went 1-1-0. The Marlins were the moneyline underdog for two Weathers starts this season -- they split the games.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (62.7%)

Padres vs Marlins Moneyline

• Miami is the underdog, +128 on the moneyline, while San Diego is a -152 favorite at home.

Padres vs Marlins Spread

• The Marlins are +1.5 on the spread (-170 to cover), and San Diego is +140 to cover the runline.

Padres vs Marlins Over/Under

• Padres versus Marlins, on May 26, has an over/under of 8, with the over being -104 and the under -118.

Bet on San Diego Padres vs. Miami Marlins on FanDuel today!

Padres vs Marlins Betting Trends

• The Padres have been victorious in 16, or 61.5%, of the 26 contests they have been chosen as favorites in this season.
• This season San Diego has been victorious 10 times in 14 chances when named as a favorite of at least -152 on the moneyline.
• The Padres and their opponents have hit the over in 21 of their 50 games with a total set by oddsmakers this season.
• The Padres have an against the spread record of 27-23-0 in 50 games with a line this season.
• The Marlins have won 17 of the 45 games they were the moneyline underdog this season (37.8%).
• In games it has played as a moneyline underdog with odds of +128 or longer, Miami has a 9-17 record (winning just 34.6% of its games).
• The Marlins have played in 51 games with a set over/under, and have combined with their opponents to go over the total 30 times (30-21-0).
• The Marlins have collected a 28-23-0 record ATS this season (covering 54.9% of the time).

Padres Player Leaders

• Fernando Tatis Jr. is hitting .282 with seven doubles, a triple, 12 home runs and 20 walks. He has an on-base percentage of .350 while slugging .513.
• Among qualified batters in MLB, his batting average ranks 34th, his on-base percentage ranks 50th, and he is 26th in slugging.
• Manny Machado has a slash line of .321/.390/.487 this season and a team-best OPS of .877.
• Among qualifying batters, his batting average places him eighth, his on-base percentage 12th, and his slugging percentage 35th.
• Machado takes a three-game streak with at least one hit into this contest. During his last five outings he is hitting .421 with two doubles, two home runs, two walks and three RBIs.
• Luis Arraez has 52 hits this season and has a slash line of .284/.318/.410.
• Gavin Sheets leads San Diego in total hits (45) this season while batting .283 with 17 extra-base hits.

Marlins Player Leaders

• Kyle Stowers has racked up an on-base percentage of .379, a slugging percentage of .543, and has 54 hits, all club-highs for the Marlins (while batting .309).
• Including all the qualified players in the majors, his batting average is 11th, his on-base percentage is 21st, and he is 10th in slugging.
• Eric Wagaman has 10 doubles, a triple, four home runs and 13 walks while batting .253. He's slugging .391 with an on-base percentage of .303.
• He is 85th in batting average, 120th in on-base percentage and 104th in slugging percentage in MLB.
• Otto Lopez has five doubles, three home runs and 14 walks while batting .221.
• Agustin Ramirez is hitting .243 with 10 doubles, six home runs and 10 walks.

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