Padres vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for March 30

Odds updated as of 5:14 a.m.

Monday's slate in the MLB includes a matchup between the San Diego Padres and the San Francisco Giants.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this matchup.

Padres vs Giants Game Info

• San Diego Padres (1-2) vs. San Francisco Giants (0-3)
• Date: Monday, March 30, 2026
• Time: 9:40 p.m. ET
• Venue: Petco Park -- San Diego, California
• Coverage: Fox Sports 1, Padres.TV, and NBCS-BA

Padres vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-118) | SF: (+100)
• Spread: SD: +1.5 (-205) | SF: -1.5 (+168)
• Total: 8.5 -- Over: (+102) | Under: (-124)

Padres vs Giants Probable Starting Pitchers

Probable Pitchers: Walker Buehler (Padres) - 0-0, 0.00 ERA vs Landen Roupp (Giants) - 0-0, 0.00 ERA

The Padres will give the nod to Walker Buehler against the Giants and Landen Roupp. In 24 games he pitched with a spread last season, Buehler and his team finished with a 12-12-0 record ATS. Buehler and his team had a 10-3 record when he pitched as a favorite last season. Last season Roupp and his team were 11-11-0 against the spread when he pitched. Roupp and his team put together a 7-7 record in the 14 games he appeared in when they were the underdog on the moneyline a season ago.

Padres vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (51.1%)

Padres vs Giants Moneyline

• San Francisco is the underdog, +100 on the moneyline, while San Diego is a -118 favorite at home.

Padres vs Giants Spread

• The Giants are 1.5-run favorites against the spread for this matchup with the Padres. The Giants are +168 to cover, while the Padres are -205 to cover as a 1.5-run underdog on the runline.

Padres vs Giants Over/Under

• The over/under for the Padres versus Giants game on March 30 has been set at 8.5, with +102 odds on the over and -124 odds on the under.

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Padres vs Giants Betting Trends

• The Padres were victorious in 54, or 60.7%, of the 89 contests they were chosen as favorites last season.
• Last year, San Diego won 52 of 85 games when listed as at least -118 on the moneyline.
• The Padres and their opponents hit the over in 70 of their 163 games with a total last season.
• The Giants were the moneyline underdog 65 times last season. They went 29-36 in those games.
• San Francisco went 22-29 when it played as a moneyline underdog with odds of +100 or longer (43.1%).
• The Giants combined with their opponents to go over the total 77 times last season for a 77-76-8 record against the over/under.

Padres Player Leaders

• Fernando Tatis Jr. ended last season with an OBP of .368 while batting .268 with 89 walks and 111 runs scored.
• Manny Machado finished with 169 hits and a slugging percentage of .460.
• Last season, Ramon Laureano finished with 24 home runs, 76 RBI and a batting average of .281 last season.
• Xander Bogaerts slashed .263/.328/.391 and finished with an OPS of .720.

Giants Player Leaders

• Rafael Devers had an OBP of .372 with 153 hits last season.
• Luis Arraez had a .392 slugging percentage while batting .292.
• Willy Adames hit .225 with 22 doubles, two triples, 30 home runs and 80 walks a season ago.
• Jung Hoo Lee hit .266 with 31 doubles, 12 triples, eight home runs and 47 walks.

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