Padres vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 4

Odds updated as of 9:12 p.m.

The San Diego Padres versus the Arizona Diamondbacks is on the MLB schedule for Monday.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Diamondbacks Game Info

• San Diego Padres (62-50) vs. Arizona Diamondbacks (53-59)
• Date: Monday, August 4, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and SDPA

Padres vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-130) | ARI: (+110)
• Spread: SD: -1.5 (+122) | ARI: +1.5 (-146)
• Total: 9 -- Over: (-120) | Under: (-102)

Padres vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: JP Sears (Padres) - 7-9, 4.95 ERA vs Brandon Pfaadt (Diamondbacks) - 10-7, 5.03 ERA

The Padres will look to JP Sears (7-9) against the Diamondbacks and Brandon Pfaadt (10-7). When Sears starts, his team is 12-10-0 against the spread this season. Sears' team has been victorious in 75% of the games he's started as the moneyline favorite with a record of 3-1. The Diamondbacks have a 12-10-0 ATS record in Pfaadt's 22 starts that had a set spread. The Diamondbacks have been the moneyline underdog in 10 of Pfaadt's starts this season, and they went 5-5 in those games.

Padres vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (51.2%)

Padres vs Diamondbacks Moneyline

• Arizona is the underdog, +110 on the moneyline, while San Diego is a -130 favorite despite being on the road.

Padres vs Diamondbacks Spread

• The Padres are 1.5-run road favorites on the runline against the Diamondbacks. The Padres are +122 to cover, and the Diamondbacks are -146.

Padres vs Diamondbacks Over/Under

• Padres versus Diamondbacks, on Aug. 4, has an over/under of 9, with the over being -120 and the under -102.

Bet on San Diego Padres vs. Arizona Diamondbacks on FanDuel today!

Padres vs Diamondbacks Betting Trends

• The Padres have been favorites in 56 games this season and have come away with the win 34 times (60.7%) in those contests.
• San Diego has a record of 29-18 when favored by -130 or more this year.
• Contests with the Padres have gone over the total set by oddsmakers in 46 of 110 chances this season.
• The Padres have an against the spread record of 61-49-0 in 110 games with a line this season.
• The Diamondbacks have won 18 of the 41 games they were the underdog on the moneyline this season (43.9%).
• When it has played as a moneyline underdog with odds of +110 or longer, Arizona has an 11-7 record (winning 61.1% of its games).
• The Diamondbacks have played in 108 games with an over/under set, and have combined with opponents to go over the total 54 times (54-48-6).
• The Diamondbacks have covered 45.4% of their games this season, going 49-59-0 ATS.

Padres Player Leaders

• Manny Machado has 129 hits to go with a slugging percentage of .501, both of which are best among San Diego hitters this season. He has a .299 batting average and an on-base percentage of .359.
• Among the qualifying hitters in MLB, his batting average ranks ninth, his on-base percentage ranks 30th, and he is 20th in slugging.
• Fernando Tatis Jr. is hitting .264 with 19 doubles, two triples, 17 home runs and 63 walks, while slugging .442 with an on-base percentage of .367.
• Among all qualifying players, he is 68th in batting average, 23rd in on-base percentage and 69th in slugging percentage.
• Luis Arraez is batting .298 with a .407 slugging percentage and 41 RBI this year.
• Arraez takes a 16-game hitting streak into this matchup. In his last 10 outings he is hitting .415 with three doubles, a home run, three walks and four RBIs.
• Xander Bogaerts has been key for San Diego with 107 hits, an OBP of .339 plus a slugging percentage of .383.
• Bogaerts enters this matchup on a four-game hitting streak. In his last five games he is hitting .263 with a walk and an RBI.

Diamondbacks Player Leaders

• Geraldo Perdomo has a .426 slugging percentage, which leads the Diamondbacks. He's batting .278 with an on-base percentage of .378.
• Including all qualifying hitters in MLB, he is 35th in batting average, 12th in on-base percentage and 82nd in slugging percentage.
• Corbin Carroll is batting .247 with 19 doubles, 14 triples, 22 home runs and 37 walks. He's slugging .543 with an on-base percentage of .323.
• Including all qualified hitters, he ranks 107th in batting average, 87th in on-base percentage and 10th in slugging percentage.
• Ketel Marte has racked up 85 hits with a .390 on-base percentage, leading the Diamondbacks in both statistics.
• Lourdes Gurriel Jr. has 21 doubles, two triples, 12 home runs and 26 walks while hitting .244.

Padres vs Diamondbacks Head to Head

• 7/10/2025: 4-3 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/9/2025: 8-2 ARI (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/8/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/7/2025: 6-3 ARI (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/15/2025: 8-2 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/14/2025: 8-7 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/13/2025: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/29/2024: 11-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/28/2024: 5-0 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 9/27/2024: 5-3 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)

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