Orioles vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for March 26

Odds updated as of 2:12 p.m.

The Baltimore Orioles and the Minnesota Twins meet for MLB Opening Day on Thursday.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Orioles vs Twins Game Info

• Baltimore Orioles (0-0) vs. Minnesota Twins (0-0)
• Date: Thursday, March 26, 2026
• Time: 3:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and Twins.TV

Orioles vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-138) | MIN: (+118)
• Spread: BAL: -1.5 (+146) | MIN: +1.5 (-176)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Orioles vs Twins Probable Starting Pitchers

Probable Pitchers: Trevor Rogers (Orioles) - 0-0, 0.00 ERA vs Joe Ryan (Twins) - 0-0, 0.00 ERA

The Orioles will call on Trevor Rogers versus the Twins and Joe Ryan. In games Rogers pitched with a spread last season, his team was 13-5-0 ATS. Rogers and his team were 5-1 when he pitched and they were the moneyline favorite. Last season Ryan and his team went 13-17-0 against the spread in games he pitched. Ryan and his team went 2-5 in the seven games he appeared in when they were the underdog on the moneyline a season ago.

Orioles vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (52.6%)

Orioles vs Twins Moneyline

• Baltimore is the favorite, -138 on the moneyline, while Minnesota is a +118 underdog on the road.

Orioles vs Twins Spread

• The Twins are +1.5 on the run line against the Orioles. The Twins are -176 to cover, and the Orioles are +146.

Orioles vs Twins Over/Under

• The over/under for the Orioles versus Twins game on March 26 has been set at 8.5, with -104 odds on the over and -118 odds on the under.

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Orioles vs Twins Betting Trends

• The Orioles came away with 31 wins in the 63 contests they were listed as the favorites last season.
• Last season Baltimore came away with a win 13 times in 23 chances when named as a favorite of at least -138 or shorter on the moneyline.
• The Orioles and their opponents hit the over in 65 of their 159 games with a total last season.
• The Twins won 26 of the 67 games they were listed as the moneyline underdog last season (38.8%).
• Minnesota went 13-19 when playing as a moneyline underdog with odds of +118 or longer (40.6%).
• The Twins combined with their opponents to go over the total 72 times last season for a 72-78-7 record against the over/under.

Orioles Player Leaders

• Last season, Pete Alonso finished with 170 hits and a slugging percentage of .524.
• Taylor Ward slashed .228/.317/.475 and finished with an OPS of .792.
• Gunnar Henderson ended last season with an OBP of .349 while batting .274 with 62 walks and 85 runs scored.
• Adley Rutschman slashed .220/.307/.366 and finished with an OPS of .673.

Twins Player Leaders

• Byron Buxton put up an on-base percentage of .327, a slugging percentage of .551, and had 129 hits last season.
• Josh Bell hit .237 with 16 doubles, a triple, 22 home runs and 57 walks.
• Trevor Larnach hit .250 with 24 doubles, a triple, 17 home runs and 53 walks a season ago.
• Brooks Lee hit .236 with 15 doubles, a triple, 16 home runs and 31 walks.

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