Orioles vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for March 26

Odds updated as of 10:13 p.m.

The Baltimore Orioles and the Minnesota Twins meet for MLB Opening Day on Thursday.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Orioles vs Twins Game Info

• Baltimore Orioles (0-0) vs. Minnesota Twins (0-0)
• Date: Thursday, March 26, 2026
• Time: 3:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and MNNT

Orioles vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BAL: (-134) | MIN: (+116)
• Spread: BAL: -1.5 (+158) | MIN: +1.5 (-192)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Orioles vs Twins Probable Starting Pitchers

Probable Pitchers: Trevor Rogers (Orioles) - 0-0, 0.00 ERA vs Joe Ryan (Twins) - 0-0, 0.00 ERA

The Orioles will call on Trevor Rogers versus the Twins and Joe Ryan. Rogers and his team were 13-5-0 ATS in games he pitched last year. Rogers appeared in six games last season as the moneyline favorite and his team finished with a record of 5-1 in those contests. Last season Ryan and his team went 13-17-0 against the spread in games he pitched. Ryan and his team went 2-5 in the seven games he pitched when they were the underdog on the moneyline a season ago.

Orioles vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (52.6%)

Orioles vs Twins Moneyline

• The Orioles vs Twins moneyline has Baltimore as a -134 favorite, while Minnesota is a +116 underdog on the road.

Orioles vs Twins Spread

• The Twins are +1.5 on the run line against the Orioles. The Twins are -192 to cover, and the Orioles are +158.

Orioles vs Twins Over/Under

• The over/under for Orioles-Twins on March 26 is 8.5. The over is -102, and the under is -120.

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Orioles vs Twins Betting Trends

• The Orioles were victorious in 31, or 49.2%, of the 63 contests they were chosen as favorites last season.
• Last year, Baltimore won 14 of 26 games when listed as at least -134 on the moneyline.
• The Orioles and their opponents hit the over in 65 of their 159 games with a total last season.
• The Twins won 38.8% of the games last season they were the moneyline underdog (26-41).
• In games it played as a moneyline underdog with odds of +116 or longer last year, Minnesota went 13-19 (40.6%).
• The Twins combined with their opponents to go over the total 72 times last season for a 72-78-7 record against the over/under.

Orioles Player Leaders

• Last season, Pete Alonso finished with 170 hits and a slugging percentage of .524.
• Taylor Ward slashed .228/.317/.475 and finished with an OPS of .792.
• Gunnar Henderson ended last season with an OBP of .349 while batting .274 with 62 walks and 85 runs scored.
• Jackson Holliday slashed .242/.314/.375 and finished with an OPS of .690.

Twins Player Leaders

• Byron Buxton put up an on-base percentage of .327, a slugging percentage of .551, and had 129 hits last season.
• Josh Bell hit .237 with 16 doubles, a triple, 22 home runs and 57 walks.
• Trevor Larnach hit .250 with 24 doubles, a triple, 17 home runs and 53 walks a season ago.
• Brooks Lee hit .236 with 15 doubles, a triple, 16 home runs and 31 walks.

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