Monday’s MLB Odds, Betting Lines and Predictions - July 21

Today's MLB schedule has several top-tier games, including a matchup between the New York Yankees and the Toronto Blue Jays. Below, we have predictions for every game.

Today's MLB Odds and Predictions

San Diego Padres at Miami Marlins Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: loanDepot park
• TV Channel: FDSFL and SDPA
• Probable Pitchers: Eury Pérez vs. Randy Vasquez
• Records: Marlins (46-52), Padres (54-45)
• Marlins Moneyline Odds: -130
• Padres Moneyline Odds: +110

numberFire Prediction

• numberFire Predicted Favorite: Marlins
• Marlins Win Probability: 53.39%
• Padres Win Probability: 46.61%

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Baltimore Orioles at Cleveland Guardians Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: Progressive Field
• TV Channel: CLEG and MASN2
• Probable Pitchers: Tanner Bibee vs. Tomoyuki Sugano
• Records: Guardians (48-50), Orioles (44-54)
• Guardians Moneyline Odds: -136
• Orioles Moneyline Odds: +116

numberFire Prediction

• numberFire Predicted Favorite: Guardians
• Guardians Win Probability: 54.45%
• Orioles Win Probability: 45.55%

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Detroit Tigers at Pittsburgh Pirates Odds, Lines & Predictions

Game Info

• When: 6:40 p.m. ET
• Where: PNC Park
• TV Channel: SportsNet PT and FDSDET
• Probable Pitchers: Paul Skenes vs. Jack Flaherty
• Records: Pirates (39-61), Tigers (60-40)
• Pirates Moneyline Odds: -126
• Tigers Moneyline Odds: +108

numberFire Prediction

• numberFire Predicted Favorite: Pirates
• Pirates Win Probability: 53.35%
• Tigers Win Probability: 46.65%

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Cincinnati Reds at Washington Nationals Odds, Lines & Predictions

Game Info

• When: 6:45 p.m. ET
• Where: Nationals Park
• TV Channel: MASN and FDSOH
• Probable Pitchers: Jake Irvin vs. Brady Singer
• Records: Nationals (39-60), Reds (52-48)
• Reds Moneyline Odds: -134
• Nationals Moneyline Odds: +114

numberFire Prediction

• numberFire Predicted Favorite: Reds
• Reds Win Probability: 59.38%
• Nationals Win Probability: 40.62%

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Boston Red Sox at Philadelphia Phillies Odds, Lines & Predictions

Game Info

• When: 6:45 p.m. ET
• Where: Citizens Bank Park
• TV Channel: NBCS-PH and NESN
• Probable Pitchers: Zack Wheeler vs. Walker Buehler
• Records: Phillies (56-43), Red Sox (54-47)
• Phillies Moneyline Odds: -215
• Red Sox Moneyline Odds: +180

numberFire Prediction

• numberFire Predicted Favorite: Phillies
• Phillies Win Probability: 65.59%
• Red Sox Win Probability: 34.41%

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New York Yankees at Toronto Blue Jays Odds, Lines & Predictions

Game Info

• When: 7:07 p.m. ET
• Where: Rogers Centre
• TV Channel: SNET and YES
• Probable Pitchers: Kevin Gausman vs. Carlos Rodon
• Records: Blue Jays (58-41), Yankees (55-44)
• Yankees Moneyline Odds: -122
• Blue Jays Moneyline Odds: +104

numberFire Prediction

• numberFire Predicted Favorite: Yankees
• Yankees Win Probability: 52.50%
• Blue Jays Win Probability: 47.50%

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Los Angeles Angels at New York Mets Odds, Lines & Predictions

Game Info

• When: 7:10 p.m. ET
• Where: Citi Field
• TV Channel: SNY and FDSW
• Probable Pitchers: Kodai Senga vs. Tyler Anderson
• Records: Mets (56-44), Angels (49-50)
• Mets Moneyline Odds: -184
• Angels Moneyline Odds: +154

numberFire Prediction

• numberFire Predicted Favorite: Mets
• Mets Win Probability: 69.62%
• Angels Win Probability: 30.38%

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San Francisco Giants at Atlanta Braves Odds, Lines & Predictions

Game Info

• When: 7:15 p.m. ET
• Where: Truist Park
• TV Channel: FDSSO and NBCS-BA
• Probable Pitchers: Bryce Elder vs. Hayden Birdsong
• Records: Braves (43-55), Giants (52-48)
• Braves Moneyline Odds: -126
• Giants Moneyline Odds: +108

numberFire Prediction

• numberFire Predicted Favorite: Braves
• Braves Win Probability: 56.23%
• Giants Win Probability: 43.77%

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Chicago White Sox at Tampa Bay Rays Odds, Lines & Predictions

Game Info

• When: 7:35 p.m. ET
• Where: George M. Steinbrenner Field
• TV Channel: FDSSUN and CHSN
• Probable Pitchers: Shane Baz vs. Sean Burke
• Records: Rays (52-48), White Sox (35-65)
• Rays Moneyline Odds: -225
• White Sox Moneyline Odds: +188

numberFire Prediction

• numberFire Predicted Favorite: Rays
• Rays Win Probability: 69.02%
• White Sox Win Probability: 30.98%

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Kansas City Royals at Chicago Cubs Odds, Lines & Predictions

Game Info

• When: 8:05 p.m. ET
• Where: Wrigley Field
• TV Channel: MLB Network, MARQ and FDSKC
• Probable Pitchers: Ryan Brasier vs. Noah Cameron
• Records: Cubs (59-40), Royals (48-52)
• Cubs Moneyline Odds: -142
• Royals Moneyline Odds: +120

numberFire Prediction

• numberFire Predicted Favorite: Cubs
• Cubs Win Probability: 66.52%
• Royals Win Probability: 33.48%

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Athletics at Texas Rangers Odds, Lines & Predictions

Game Info

• When: 8:05 p.m. ET
• Where: Globe Life Field
• TV Channel: MLB Network, RSN and NBCS-CA
• Probable Pitchers: Jack Leiter vs. Jacob Lopez
• Records: Rangers (50-50), Athletics (42-59)
• Rangers Moneyline Odds: -122
• Athletics Moneyline Odds: +104

numberFire Prediction

• numberFire Predicted Favorite: Rangers
• Rangers Win Probability: 51.44%
• Athletics Win Probability: 48.56%

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St. Louis Cardinals at Colorado Rockies Odds, Lines & Predictions

Game Info

• When: 8:40 p.m. ET
• Where: Coors Field
• TV Channel: COLR and FDSMW
• Probable Pitchers: Austin Gomber vs. Michael McGreevy
• Records: Rockies (24-75), Cardinals (51-49)
• Cardinals Moneyline Odds: -154
• Rockies Moneyline Odds: +130

numberFire Prediction

• numberFire Predicted Favorite: Cardinals
• Cardinals Win Probability: 62.82%
• Rockies Win Probability: 37.18%

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Houston Astros at Arizona Diamondbacks Odds, Lines & Predictions

Game Info

• When: 9:40 p.m. ET
• Where: Chase Field
• TV Channel: ARID and SCHN
• Probable Pitchers: Zac Gallen vs. Colton Gordon
• Records: Diamondbacks (50-50), Astros (57-42)
• Diamondbacks Moneyline Odds: -144
• Astros Moneyline Odds: +122

numberFire Prediction

• numberFire Predicted Favorite: Diamondbacks
• Diamondbacks Win Probability: 50.68%
• Astros Win Probability: 49.32%

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Milwaukee Brewers at Seattle Mariners Odds, Lines & Predictions

Game Info

• When: 9:40 p.m. ET
• Where: T-Mobile Park
• TV Channel: ROOT Sports NW and FDSWI
• Probable Pitchers: George Kirby vs. Brandon Woodruff
• Records: Mariners (53-46), Brewers (59-40)
• Mariners Moneyline Odds: -130
• Brewers Moneyline Odds: +110

numberFire Prediction

• numberFire Predicted Favorite: Mariners
• Mariners Win Probability: 53.77%
• Brewers Win Probability: 46.23%

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Minnesota Twins at Los Angeles Dodgers Odds, Lines & Predictions

Game Info

• When: 10:10 p.m. ET
• Where: Dodger Stadium
• TV Channel: SportsNet LA and MNNT
• Probable Pitchers: Shohei Ohtani vs. David Festa
• Records: Dodgers (58-42), Twins (48-51)
• Dodgers Moneyline Odds: -162
• Twins Moneyline Odds: +136

numberFire Prediction

• numberFire Predicted Favorite: Dodgers
• Dodgers Win Probability: 56.91%
• Twins Win Probability: 43.09%

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All MLB win probability predictions and picks are according to numberFire.