Michigan vs Alabama College Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament Sweet 16

The No. 4-seed Alabama Crimson Tide (25-9) head into a Sweet 16 matchup against the No. 1 Michigan Wolverines (33-3) on Friday at 7:50 p.m. ET as the NCAA Tournament continues at United Center airing on TBS.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Michigan vs. Alabama Game Info and Odds

• Game day: Friday, March 27, 2026
• Game time: 7:50 p.m. ET
• TV channel: TBS
• Location: Chicago, Illinois
• Arena: United Center

Take a look at some betting insights for Michigan (-9.5) versus Alabama on Friday. The over/under has been set at 173.5 points for this game.

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Michigan vs. Alabama: ATS Betting Stats and Trends

• Michigan has compiled a 16-20-0 ATS record so far this year.
• Alabama has covered 16 times in 34 games with a spread this season.
• Against the spread, the Wolverines have fared better at home, covering eight times in 15 home games, and four times in 11 road games.
• The Crimson Tide's winning percentage against the spread at home is .400 (6-9-0). On the road, it is .500 (5-5-0).

Michigan vs. Alabama: Moneyline Betting Stats

• Michigan has been victorious in 31, or 91.2%, of the 34 contests it has been chosen as moneyline favorites in this season.
• The Wolverines have a mark of 24-1 in contests where sportsbooks favor them by -521 or better on the moneyline.
• Alabama is 5-4 in games it was the underdog on the moneyline (winning 55.6% of those games).
• The Crimson Tide have not played a game this season with moneyline odds of +375 or longer.
• Bookmakers have implied with the moneyline set for this matchup that Michigan has a 83.9% chance of pulling out a win.

Michigan vs. Alabama Head-to-Head Comparison

• Offensively, Michigan was the 75th-ranked squad in college basketball (78 points per game) last year. Defensively, it was 160th (71.5 points conceded per game).
• On the boards, Michigan was 34th in the nation in rebounds (35 per game) last year. It was 114th in rebounds conceded (30.2 per game).
• Michigan was 46th in the country in assists (15.8 per game) last season.
• Last year, Michigan was 14th-worst in the country in turnovers committed (13.6 per game) and 240th in turnovers forced (10.6).
• Although Alabama ceded 81.3 points per game (third-worst in college basketball) on defense last year, its offense was very good, as it ranked best in college basketball by averaging 90.7 points per game.
• Alabama ranked third-best in college basketball by pulling down 38.8 boards per game. In terms of rebounds allowed, it ranked 290th in college basketball (33 allowed per contest).
• Alabama was one of the top teams in college basketball when it comes to assists, as it collected 17.1 per game (13th-best in college basketball).
• Alabama averaged 12.1 turnovers per game (267th-ranked in college basketball). It forced 10 turnovers per contest (305th-ranked).

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