Mariners vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for March 28

Odds updated as of 9:12 p.m.

The MLB schedule on Saturday includes the Seattle Mariners facing the Cleveland Guardians.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this matchup.

Mariners vs Guardians Game Info

• Seattle Mariners (1-1) vs. Cleveland Guardians (1-1)
• Date: Saturday, March 28, 2026
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Mariners.TV and CleGuardians.TV

Mariners vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-178) | CLE: (+150)
• Spread: SEA: -1.5 (+126) | CLE: +1.5 (-152)
• Total: 7 -- Over: (-102) | Under: (-120)

Mariners vs Guardians Probable Starting Pitchers

Probable Pitchers: Bryan Woo (Mariners) - 0-0, 0.00 ERA vs Joey Cantillo (Guardians) - 0-0, 0.00 ERA

The Mariners will give the nod to Bryan Woo versus the Guardians and Joey Cantillo. Woo and his team were 13-17-0 against the spread when he pitched last season. Woo and his team were 13-10 when he pitched and they were the moneyline favorite. Last season Cantillo and his team finished 7-6-0 against the spread when he pitched. Cantillo and his team went 3-2 in the five games he appeared in when they were the underdog on the moneyline a season ago.

Mariners vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (66.4%)

Mariners vs Guardians Moneyline

• Looking at the moneyline for Guardians-Mariners, Cleveland is the underdog at +150, and Seattle is -178 playing at home.

Mariners vs Guardians Spread

• The Mariners are favored by 1.5 runs at home against the Guardians. The Mariners are +126 to cover the spread, while the Guardians are -152.

Mariners vs Guardians Over/Under

• The over/under for Mariners-Guardians on March 28 is 7. The over is -102, and the under is -120.

Bet on Seattle Mariners vs. Cleveland Guardians on FanDuel today!

Mariners vs Guardians Betting Trends

• The Mariners were chosen as favorites in 114 games last year and walked away with the win 66 times (57.9%) in those games.
• Last year, Seattle won 21 of 28 games when listed as at least -178 on the moneyline.
• The Mariners and their opponents hit the over in 91 of their 168 games with a total last season.
• The Guardians won 41 of the 88 games they were the underdog on the moneyline last season (46.6%).
• Cleveland went 4-8 when playing as a moneyline underdog with odds of +150 or longer (33.3%).
• The Guardians combined with their opponents to hit the over on the total 69 times last season for a 69-85-7 record against the over/under.

Mariners Player Leaders

• Cal Raleigh had 147 hits and an OBP of .359 last season.
• Julio Rodriguez hit 32 homers while driving in 95 runs.
• Last season, Josh Naylor finished with 20 home runs, 92 RBI and a batting average of .295 last season.
• Randy Arozarena slashed .238/.334/.426 and finished with an OPS of .760.

Guardians Player Leaders

• Jose Ramirez put up an OBP of .360 with 168 hits last season.
• Steven Kwan had a .374 slugging percentage while batting .272.
• Kyle Manzardo had 19 doubles, two triples, 27 home runs and 48 walks while batting .234 last season.
• Angel Martinez hit .224 with 23 doubles, two triples, 11 home runs and 23 walks.

Mariners vs Guardians Head to Head

• 3/27/2026: 5-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 3/26/2026: 6-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/31/2025: 4-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/30/2025: 4-3 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/29/2025: 5-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/15/2025: 6-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/14/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/13/2025: 7-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/20/2024: 6-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/19/2024: 8-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)

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