Mariners vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for March 27

Odds updated as of 9:12 p.m.

The Seattle Mariners are among the MLB teams busy on Friday, up against the Cleveland Guardians.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Mariners vs Guardians Game Info

• Seattle Mariners (0-1) vs. Cleveland Guardians (1-0)
• Date: Friday, March 27, 2026
• Time: 9:45 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Apple TV+

Mariners vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-178) | CLE: (+150)
• Spread: SEA: -1.5 (+126) | CLE: +1.5 (-152)
• Total: 7 -- Over: (-105) | Under: (-115)

Mariners vs Guardians Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 0-0, 0.00 ERA vs Gavin Williams (Guardians) - 0-0, 0.00 ERA

The Mariners will call on George Kirby against the Guardians and Gavin Williams. Kirby and his team were 12-15-0 ATS in games he pitched last year. Kirby and his team won as favorites in 50% of his 22 appearances last season with a moneyline. Last season in games Williams pitched his team went 18-14-0 against the spread. Williams and his team put together a 11-11 record in the 22 games he appeared in when they were moneyline underdogs a season ago.

Mariners vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (68.6%)

Mariners vs Guardians Moneyline

• The Mariners vs Guardians moneyline has Seattle as a -178 favorite, while Cleveland is a +150 underdog on the road.

Mariners vs Guardians Spread

• The Mariners are 1.5-run home favorites on the runline against the Guardians. The Mariners are +126 to cover, and the Guardians are -152.

Mariners vs Guardians Over/Under

• The Mariners-Guardians game on March 27 has been given an over/under of 7 runs. The over is set at -105 and the under at -115.

Bet on Seattle Mariners vs. Cleveland Guardians on FanDuel today!

Mariners vs Guardians Betting Trends

• The Mariners were victorious in 66, or 57.9%, of the 114 contests they were chosen as favorites last season.
• Last year, Seattle won 21 of 28 games when listed as at least -178 on the moneyline.
• The Mariners and their opponents hit the over in 91 of their 168 games with a total last season.
• The Guardians won 41 of the 88 games they were the underdog on the moneyline last season (46.6%).
• Cleveland went 4-8 in games it played as a moneyline underdog with odds of +150 or longer (33.3%).
• The Guardians played in 161 games with an over/under set last season, and combined with their opponents to go over the total 69 times (69-85-7).

Mariners Player Leaders

• Cal Raleigh had 147 hits and an OBP of .359 last season.
• Julio Rodriguez had an OPS of .798, fueled by an OBP of .324 and a slugging percentage of .474.
• Josh Naylor ended his last campaign with 160 hits, an OBP of .353, plus a slugging percentage of .462.
• Randy Arozarena slashed .238/.334/.426 and finished with an OPS of .760.

Guardians Player Leaders

• Jose Ramirez accumulated an OBP of .360 with 168 hits last season.
• Steven Kwan slugged .374 while batting .272.
• Kyle Manzardo had 19 doubles, two triples, 27 home runs and 48 walks while hitting .234 last season.
• Angel Martinez hit .224 with 23 doubles, two triples, 11 home runs and 23 walks.

Mariners vs Guardians Head to Head

• 3/26/2026: 6-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/31/2025: 4-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/30/2025: 4-3 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/29/2025: 5-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/15/2025: 6-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/14/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/13/2025: 7-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/20/2024: 6-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/19/2024: 8-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/18/2024: 8-5 SEA (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)

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