Mariners vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for March 27

Odds updated as of 5:13 a.m.

Friday's slate in the MLB includes a matchup between the Seattle Mariners and the Cleveland Guardians.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Mariners vs Guardians Game Info

• Seattle Mariners (0-1) vs. Cleveland Guardians (1-0)
• Date: Friday, March 27, 2026
• Time: 9:45 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Apple TV+

Mariners vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-180) | CLE: (+152)
• Spread: SEA: -1.5 (+122) | CLE: +1.5 (-146)
• Total: 7 -- Over: (-115) | Under: (-105)

Mariners vs Guardians Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 0-0, 0.00 ERA vs Gavin Williams (Guardians) - 0-0, 0.00 ERA

The Mariners will call on George Kirby versus the Guardians and Gavin Williams. Kirby and his team were 12-15-0 against the spread when he pitched last season. Kirby and his team won as favorites in 50% of his 22 appearances last season with a moneyline. Last season Williams and his team had an 18-14-0 record against the spread in games he pitched. Williams and his team put together a 11-11 record in the 22 games he pitched when they were moneyline underdogs a season ago.

Mariners vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (68.9%)

Mariners vs Guardians Moneyline

• Looking at the moneyline for Guardians-Mariners, Cleveland is the underdog at +152, and Seattle is -180 playing at home.

Mariners vs Guardians Spread

• The Guardians are +1.5 on the spread (-146 to cover), and Seattle is +122 to cover the runline.

Mariners vs Guardians Over/Under

• Mariners versus Guardians, on March 27, has an over/under of 7, with the over being -115 and the under -105.

Bet on Seattle Mariners vs. Cleveland Guardians on FanDuel today!

Mariners vs Guardians Betting Trends

• The Mariners won in 66, or 57.9%, of the 114 contests they were named as odds-on favorites in the last year.
• Last year, Seattle won 21 of 25 games when listed as at least -180 on the moneyline.
• The Mariners and their opponents hit the over in 91 of their 168 games with a total last season.
• The Guardians were the underdog on the moneyline 88 times last season. They finished 41-47 in those games.
• When playing as a moneyline underdog with odds of +152 or longer last year, Cleveland went 4-8 (33.3%).
• The Guardians played in 161 games with a set over/under last season, and combined with their opponents to go over the total 69 times (69-85-7).

Mariners Player Leaders

• Cal Raleigh had 147 hits and an OBP of .359 last season.
• Julio Rodriguez hit 32 homers while driving in 95 runs.
• Last season, Josh Naylor finished with 20 home runs, 92 RBI and a batting average of .295 last season.
• Randy Arozarena slashed .238/.334/.426 and finished with an OPS of .760.

Guardians Player Leaders

• Jose Ramirez put up an OBP of .360 with 168 hits last season.
• Steven Kwan had a .374 slugging percentage while batting .272.
• Kyle Manzardo had 19 doubles, two triples, 27 home runs and 48 walks while batting .234 last season.
• Angel Martinez hit .224 with 23 doubles, two triples, 11 home runs and 23 walks.

Mariners vs Guardians Head to Head

• 3/26/2026: 6-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/31/2025: 4-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/30/2025: 4-3 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/29/2025: 5-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/15/2025: 6-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/14/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/13/2025: 7-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/20/2024: 6-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/19/2024: 8-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/18/2024: 8-5 SEA (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)

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