Hornets vs. Grizzlies Prediction, Odds, Picks, Best Bets for March 21

Hornets vs. Grizzlies Game Info

• Date: Saturday, March 21, 2026
• Time: 7 p.m. ET
• Venue: Spectrum Center -- Charlotte, North Carolina
• Coverage: FDSSE

The Memphis Grizzlies (24-45) visit the Charlotte Hornets (36-34) after losing five road games in a row. The Hornets are heavy favorites by 18.5 points in the contest, which starts at 7 p.m. ET on Saturday, March 21, 2026. The point total is 233.5 for the matchup.

Hornets vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Hornets vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Hornets win (80.4%)

Hornets vs. Grizzlies Betting Trends

• The Hornets are 42-27-1 against the spread this season.
• The Grizzlies have 32 wins against the spread in 69 games this year.
• Hornets games have finished with a final combined score above the over/under 28 times out of 69 chances this season.
• Grizzlies games this season have gone over the total in 33 of 69 opportunities (47.8%).
• Charlotte has done a better job covering the spread in home games (20-12-1) than it has in road affairs (22-15-0).
• The Hornets have exceeded the over/under in 12 of 33 home games (36.4%). They've done better in road games, eclipsing the total in 16 of 37 matchups (43.2%).
• Memphis has performed better against the spread at home (16-18-0) than away (16-17-2) this year.
• Looking at the over/under, Grizzlies games have finished over 18 of 34 times at home (52.9%), and 15 of 35 away (42.9%).

Hornets Leaders

• LaMelo Ball averages 19.5 points, 4.9 boards and 7.1 assists.
• Kon Knueppel averages 19.3 points, 5.3 boards and 3.4 assists.
• Miles Bridges averages 17.4 points, 5.9 boards and 3.3 assists, shooting 44.7% from the floor and 33.2% from beyond the arc, with 2 made 3-pointers per contest.
• Brandon Miller is averaging 20.4 points, 3.5 assists and 5 boards.
• Moussa Diabate's numbers on the season are 8 points, 8.7 boards and 1.9 assists per game, shooting 61.8% from the field.

Grizzlies Leaders

• Cam Spencer's numbers on the season are 11.4 points, 2.6 rebounds and 5.4 assists per contest. He is also sinking 47.9% of his shots from the floor and 44.6% from beyond the arc (fourth in league), with an average of 2.1 triples.
• The Grizzlies are getting 13.4 points, 6.2 rebounds and 2.8 assists per game from Cedric Coward.
• Per game, Jaylen Wells provides the Grizzlies 12.7 points, 3.3 boards and 1.6 assists, plus 0.9 steals and 0.1 blocks.
• The Grizzlies are getting 7.1 points, 2 boards and 3.9 assists per game from Walter Clayton Jr.
• GG Jackson averages 11.3 points, 4.3 rebounds and 1.4 assists. He is making 49.4% of his shots from the field and 33.1% from beyond the arc, with 1.1 treys per game.

For more NBA betting insights, check out FanDuel Research's NBA home page.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Watch FanDuel TV's NBA show "Run It Back" with Lou Williams, Michelle Beadle, DeMarcus "Boogie" Cousins and Chandler Parsons weekdays at 10am ET on FanDuel TV, the Run It Back YouTube page, or download the podcast here: fanduel.com/research/tv-and-podcast.