Guardians vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for July 23

Odds updated as of 1:11 p.m.

The Thursday schedule in MLB includes a matchup between the Cleveland Guardians and the Minnesota Twins.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Guardians vs Twins Game Info

• Cleveland Guardians (54-49) vs. Minnesota Twins (50-53)
• Date: Thursday, July 23, 2026
• Time: 1:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and Twins.TV

Guardians vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-144) | MIN: (+122)
• Spread: CLE: -1.5 (+158) | MIN: +1.5 (-192)
• Total: 7.5 -- Over: (-102) | Under: (-120)

Guardians vs Twins Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 10-5, 4.00 ERA vs Taj Bradley (Twins) - 9-4, 3.85 ERA

This contest's pitching matchup is set, as the Guardians will send Gavin Williams (10-5) to the mound, while Taj Bradley (9-4) will get the nod for the Twins. Williams and his team have a record of 10-9-0 against the spread when he starts. Williams' team is 9-5 this season when he starts and they are the moneyline favorite. The Twins are 12-6-0 ATS in Bradley's 18 starts that had a set spread. The Twins have a 7-4 record in Bradley's 11 starts this season when they were the moneyline underdog.

Guardians vs Twins Moneyline

• Looking at the moneyline for Guardians-Twins, Cleveland is the favorite at -144, and Minnesota is +122 playing on the road.

Guardians vs Twins Spread

• The Twins are +1.5 on the spread (-192 to cover), and Cleveland is +158 to cover the runline.

Guardians vs Twins Over/Under

• The over/under for Guardians-Twins on July 23 is 7.5. The over is -102, and the under is -120.

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Guardians vs Twins Betting Trends

• The Guardians have won in 27, or 51.9%, of the 52 contests they have been named as odds-on favorites in this year.
• This season Cleveland has come away with a win nine times in 14 chances when named as a favorite of at least -144 on the moneyline.
• The Guardians' games have gone over the total in 47 of their 97 opportunities.
• The Guardians are 48-49-0 against the spread in their 97 games with a line set by sportsbooks this season.
• The Twins have won 45.3% of the games this season they were the underdog on the moneyline (29-35).
• Minnesota has a 13-16 record (winning 44.8% of its games) when playing as a moneyline underdog of +122 or longer.
• The Twins have played in 101 games with an over/under set, and have combined with opponents to go over the total 59 times (59-40-2).
• The Twins have gone 55-46-0 against the spread this season.

Guardians Player Leaders

• Brayan Rocchio has an OPS of .746, fueled by an OBP of .338 and a team-best slugging percentage of .409 this season. He has a .275 batting average.
• Among qualifying hitters, he ranks 41st in batting average, his on-base percentage ranks 64th, and he is 92nd in slugging.
• Rocchio will look for his sixth straight game with a hit in this contest. During his last five outings he is batting .318 with a double, a home run and four RBIs.
• Chase DeLauter leads the Guardians in OBP (.351) and total hits (93) this season. He's batting .287 while slugging .454.
• He is 20th in batting average, 46th in on-base percentage and 52nd in slugging among qualified batters.
• DeLauter brings a seven-game streak with at least one hit into this matchup. In his last 10 games he is hitting .341 with three doubles, three home runs, three walks and eight RBIs.
• Jose Ramirez has collected 66 base hits, an OBP of .340 and a slugging percentage of .418 this season.
• Ramirez brings a two-game hitting streak into this game. In his last five games he is hitting .286 with a double and two RBIs.
• Steven Kwan has been key for Cleveland with 78 hits, an OBP of .350 plus a slugging percentage of .304.
• Kwan has hit safely in two straight games. In his last five games he is hitting .474 with two doubles, three walks and two RBIs.

Twins Player Leaders

• Brooks Lee has a .436 slugging percentage, which leads the Twins. He's batting .254 with an on-base percentage of .310.
• Including all qualifying hitters in the big leagues, his batting average puts him 80th, his on-base percentage is 110th, and he is 66th in slugging.
• Lee hopes to build on a five-game hitting streak in this matchup. During his last five outings he is hitting .333 with a triple, a home run and five RBIs.
• Byron Buxton has collected 86 hits to lead his team. He has a batting average of .275 while slugging .572 with an on-base percentage of .330.
• Including all qualified hitters, he ranks 41st in batting average, 77th in on-base percentage and third in slugging percentage.
• Josh Bell has put up a slugging percentage of .425, a team-best for the Twins.
• Kody Clemens is hitting .240 with 19 doubles, three triples, 18 home runs and 22 walks.

Guardians vs Twins Head to Head

• 7/22/2026: 10-6 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/21/2026: 5-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/20/2026: 13-4 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/9/2026: 5-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/8/2026: 6-5 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/7/2026: 3-1 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/10/2026: 5-4 MIN (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/8/2026: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/21/2025: 6-2 MIN (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/20/2025: 8-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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