Guardians vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 30

Odds updated as of 1:12 a.m.

In MLB action on Saturday, the Cleveland Guardians take on the Boston Red Sox.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Red Sox Game Info

• Cleveland Guardians (34-25) vs. Boston Red Sox (23-33)
• Date: Saturday, May 30, 2026
• Time: 4:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and NESN

Guardians vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-134) | BOS: (+114)
• Spread: CLE: -1.5 (+172) | BOS: +1.5 (-210)
• Total: 6.5 -- Over: (-122) | Under: (+100)

Guardians vs Red Sox Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 6-1, 2.24 ERA vs Sonny Gray (Red Sox) - 5-1, 3.27 ERA

The Guardians will call on Parker Messick (6-1) against the Red Sox and Sonny Gray (5-1). When Messick starts, his team is 8-3-0 against the spread this season. Messick's team has a record of 6-2 this season when he starts and they are the favorite on the moneyline. When Gray starts, the Red Sox are 6-3-0 against the spread. The Red Sox have not been a moneyline underdog when Gray starts this season.

Guardians vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Red Sox win (50.3%)

Guardians vs Red Sox Moneyline

• Cleveland is a -134 favorite on the moneyline, while Boston is a +114 underdog on the road.

Guardians vs Red Sox Spread

• The Red Sox are at +1.5 on the runline against the Guardians. The Red Sox are -210 to cover the spread, and the Guardians are +172.

Guardians vs Red Sox Over/Under

• An over/under of 6.5 has been set for Guardians-Red Sox on May 30, with the over being -122 and the under +100.

Bet on Cleveland Guardians vs. Boston Red Sox on FanDuel today!

Guardians vs Red Sox Betting Trends

• The Guardians have come away with 19 wins in the 32 contests they have been listed as the favorites in this season.
• Cleveland has a record of 10-6 when favored by -134 or more this year.
• The Guardians' games have gone over the total in 27 of their 55 opportunities.
• The Guardians are 28-27-0 against the spread in their 55 games with a line set by sportsbooks this season.
• The Red Sox are 6-13 in games they were listed as the moneyline underdog (winning 31.6% of those games).
• Boston has a 3-6 record (winning only 33.3% of its games) when it has played as a moneyline underdog of +114 or longer.
• The Red Sox have had an over/under set by oddsmakers 56 times, and have combined with opponents to go over the total in 25 of those games (25-30-1).
• The Red Sox have collected a 23-33-0 record ATS this season.

Guardians Player Leaders

• Jose Ramirez is hitting .227 with 12 doubles, eight home runs and 38 walks. He has an on-base percentage of .341 while slugging .394.
• Among all qualifying hitters, he ranks 120th in batting average, his on-base percentage ranks 67th, and he is 92nd in slugging.
• Chase DeLauter is hitting .265 with 11 doubles, a triple, seven home runs and 25 walks. He's slugging .439 with an on-base percentage of .345.
• He ranks 59th in batting average, 58th in on-base percentage and 57th in slugging among qualifying hitters.
• DeLauter brings a three-game streak with at least one hit into this contest. During his last five outings he is hitting .263 with a walk and an RBI.
• Brayan Rocchio has a team-best OPS of .788, fueled by a slash line of .293/.374/.414 this season.
• Angel Martinez leads Cleveland with 45 hits, batting .246 this season with 19 extra-base hits.
• Martinez heads into this game on a two-game hitting streak. During his last five outings he is hitting .211 with a double and three RBIs.

Red Sox Player Leaders

• Willson Contreras has put up an on-base percentage of .383 and has 56 hits, both team-best figures for the Red Sox. He's batting .290 and slugging .513.
• Including all the qualified players in the majors, his batting average ranks 25th, his on-base percentage is 21st, and he is 20th in slugging.
• Contreras heads into this game on a 12-game hitting streak. During his last 10 outings he is batting .436 with two triples, two home runs, two walks and eight RBIs.
• Wilyer Abreu's .425 slugging percentage leads his team. He has a batting average of .280 with an on-base percentage of .343.
• Including all qualifying players, he ranks 35th in batting average, 64th in on-base percentage and 70th in slugging percentage.
• Ceddanne Rafaela is batting .277 with 10 doubles, two triples, five home runs and 12 walks.
• Jarren Duran is batting .214 with nine doubles, a triple, eight home runs and 16 walks.

Guardians vs Red Sox Head to Head

• 5/29/2026: 4-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/3/2025: 8-1 CLE (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/2/2025: 11-7 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 9/1/2025: 6-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 4/27/2025: 13-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/26/2025: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/26/2025: 5-4 CLE (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/25/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/24/2024: 8-0 BOS (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/23/2024: 4-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)

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