Guardians vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 14

Odds updated as of 6:12 p.m.

MLB action on Friday includes the Cleveland Guardians playing the San Diego Padres.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Guardians vs Padres Game Info

• Cleveland Guardians (59-63) vs. San Diego Padres (65-57)
• Date: Friday, August 14, 2026
• Time: 7:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and Padres.TV

Guardians vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-116) | SD: (+106)
• Spread: CLE: +1.5 (-230) | SD: -1.5 (+188)
• Total: 7 -- Over: (-118) | Under: (-104)

Guardians vs Padres Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 11-6, 3.55 ERA vs Michael King (Padres) - 7-8, 3.37 ERA

The Guardians will call on Gavin Williams (11-6) versus the Padres and Michael King (7-8). Williams' team is 11-12-0 against the spread this season in his starts. Williams' team has won 55.6% of his starts when they are favored on the moneyline (10-8). The Padres have an 8-16-0 record against the spread in King's starts. The Padres have a 3-6 record in King's nine starts this season when they were the underdog on the moneyline.

Guardians vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (52.7%)

Guardians vs Padres Moneyline

• The Guardians vs Padres moneyline has Cleveland as a -116 favorite, while San Diego is a +106 underdog on the road.

Guardians vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Guardians. The Padres are +188 to cover, while the Guardians are -230 to cover as a 1.5-run underdog on the runline.

Guardians vs Padres Over/Under

• An over/under of 7 has been set for Guardians-Padres on Aug. 14, with the over being -118 and the under -104.

Bet on Cleveland Guardians vs. San Diego Padres on FanDuel today!

Guardians vs Padres Betting Trends

• The Guardians have been chosen as favorites in 65 games this year and have walked away with the win 30 times (46.2%) in those games.
• Cleveland has a record of 29-31 in contests when bookmakers favor them by -116 or more on the moneyline.
• The Guardians and their opponents have hit the over in 57 of their 116 games with a total set by oddsmakers this season.
• The Guardians are 55-61-0 against the spread in their 116 games that had a posted line this season.
• The Padres have compiled a 33-33 record in games they were the underdog on the moneyline (winning 50% of those games).
• San Diego has a 22-26 record (winning 45.8% of its games) when playing as a moneyline underdog of +106 or longer.
• The Padres have combined with opponents to go over the total 55 times this season for a 55-65-2 record against the over/under.
• The Padres have covered 56.6% of their games this season, going 69-53-0 against the spread.

Guardians Player Leaders

• Chase DeLauter leads Cleveland with 112 hits and a team-best slugging percentage of .445. He's batting .285 with an on-base percentage of .359.
• Among all qualified hitters in baseball, he is 17th in batting average, 33rd in on-base percentage, and 55th in slugging.
• DeLauter hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .364 with a double, a home run, two walks and an RBI.
• Jose Ramirez has 18 doubles, 10 home runs and 53 walks. He's batting .231 and slugging .377 with an on-base percentage of .338.
• His batting average is 116th among qualified players, his on-base percentage 58th, and his slugging percentage 115th.
• Brayan Rocchio has 105 hits this season and has a slash line of .252/.315/.367.
• Rocchio has recorded a hit in two straight games. During his last five outings he is hitting .200 with .
• Steven Kwan has 103 hits this season and a team-best OBP of .366.

Padres Player Leaders

• Fernando Tatis Jr. has racked up a team-high OBP (.353) and slugging percentage (.420). He's batting .281.
• Including all qualifying hitters in the big leagues, he is 25th in batting average, 40th in on-base percentage and 77th in slugging percentage.
• Manny Machado is hitting .213 with 20 doubles, 23 home runs and 55 walks. He's slugging .414 with an on-base percentage of .296.
• His batting average is 135th among all qualified players, his on-base percentage is 126th, and he is 85th in slugging.
• Jackson Merrill is leading the Padres with 114 hits.
• Xander Bogaerts is hitting .221 with 11 doubles, 10 home runs and 54 walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!