Giants vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 6

Odds updated as of 12:12 p.m.

The San Francisco Giants are among the MLB squads playing on Wednesday, versus the Pittsburgh Pirates.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Giants vs Pirates Game Info

• San Francisco Giants (57-57) vs. Pittsburgh Pirates (49-65)
• Date: Wednesday, August 6, 2025
• Time: 12:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and NBCS-BA

Giants vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-154) | PIT: (+130)
• Spread: SF: -1.5 (+106) | PIT: +1.5 (-128)
• Total: 8 -- Over: (-110) | Under: (-110)

Giants vs Pirates Probable Starting Pitchers

Probable Pitchers: Robbie Ray (Giants) - 9-5, 2.85 ERA vs Andrew Heaney (Pirates) - 5-9, 4.89 ERA

The Giants will give the ball to Robbie Ray (9-5, 2.85 ERA), who is eyeing win No. 10 on the season, and the Pirates will turn to Andrew Heaney (5-9, 4.89 ERA). Ray's team is 14-9-0 against the spread in his starts this season. When Ray starts a game and his team is the favorite on the moneyline, they have a record of 11-4. The Pirates have a 6-11-0 record against the spread in Heaney's starts. The Pirates have been the underdog on the moneyline in 13 of Heaney's starts this season, and they went 4-9 in those games.

Giants vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (52.9%)

Giants vs Pirates Moneyline

• The moneyline numbers for Giants vs. Pirates reveal San Francisco as the favorite (-154) and Pittsburgh as the underdog (+130) despite being the home team.

Giants vs Pirates Spread

• The Giants are 1.5-run road favorites on the runline against the Pirates. The Giants are +106 to cover, and the Pirates are -128.

Giants vs Pirates Over/Under

• The over/under for the Giants versus Pirates game on Aug. 6 has been set at 8, with -110 odds on the over and -110 odds on the under.

Bet on San Francisco Giants vs. Pittsburgh Pirates on FanDuel today!

Giants vs Pirates Betting Trends

• The Giants have come away with 36 wins in the 70 contests they have been listed as the favorites in this season.
• This year San Francisco has won 15 of 30 games when listed as at least -154 on the moneyline.
• Contests with the Giants have gone over the total set by oddsmakers in 53 of 114 chances this season.
• The Giants are 48-66-0 against the spread in their 114 games with a line set by sportsbooks this season.
• The Pirates have won 31 of the 73 games they were listed as the moneyline underdog this season (42.5%).
• When it has played as a moneyline underdog with odds of +130 or longer, Pittsburgh has a 12-23 record (winning only 34.3% of its games).
• The Pirates have played in 106 games with a set over/under, and have combined with opponents to go over the total 43 times (43-60-3).
• The Pirates have collected a 56-50-0 record ATS this season (covering 52.8% of the time).

Giants Player Leaders

• Rafael Devers leads San Francisco with 110 hits and an OBP of .377 this season. He has a .256 batting average and a slugging percentage of .458.
• Among qualified hitters in baseball, he is 86th in batting average, 13th in on-base percentage, and 58th in slugging.
• Jung Hoo Lee has 26 doubles, nine triples, six home runs and 38 walks. He's batting .258 and slugging .410 with an on-base percentage of .326.
• His batting average ranks 79th among qualified players, his on-base percentage 79th, and his slugging percentage 94th.
• Lee has picked up at least one hit in five straight games. In his last five games he is hitting .450 with four doubles, a triple, a walk and three RBIs.
• Willy Adames has 98 hits this season and has a slash line of .232/.318/.412.
• Heliot Ramos has an OPS of .774, fueled by an OBP of .351 and a team-best slugging percentage of .423 this season.
• Ramos has safely hit in six games in a row. In his last 10 games he is hitting .325 with a double, seven walks and an RBI.

Pirates Player Leaders

• Oneil Cruz has racked up 78 hits, a team-high for the Pirates. He's batting .209 and slugging .406 with an on-base percentage of .305.
• Including all the qualified players in the big leagues, he ranks 157th in batting average, 122nd in on-base percentage and 98th in slugging percentage.
• Bryan Reynolds' .377 slugging percentage leads his team. He has a batting average of .239 with an on-base percentage of .297.
• Including all qualifying hitters, he ranks 119th in batting average, 137th in on-base percentage and 129th in slugging percentage.
• Andrew McCutchen a has .325 on-base percentage to pace the Pirates.
• Isiah Kiner-Falefa is batting .271 with 14 doubles, two triples, a home run and 15 walks.

Giants vs Pirates Head to Head

• 8/5/2025: 8-1 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/4/2025: 5-4 PIT (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/30/2025: 2-1 PIT (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/29/2025: 3-1 PIT (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 7/28/2025: 6-5 PIT (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/23/2024: 7-6 SF (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/22/2024: 9-5 SF (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/21/2024: 7-6 PIT (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/28/2024: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/27/2024: 4-3 PIT (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)

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