Giants vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 6

Odds updated as of 9:11 p.m.

The San Francisco Giants versus the Pittsburgh Pirates is on the MLB schedule for Wednesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this matchup.

Giants vs Pirates Game Info

• San Francisco Giants (56-57) vs. Pittsburgh Pirates (49-64)
• Date: Wednesday, August 6, 2025
• Time: 12:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and NBCS-BA

Giants vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-156) | PIT: (+132)
• Spread: SF: -1.5 (+114) | PIT: +1.5 (-137)
• Total: 8 -- Over: (-105) | Under: (-115)

Giants vs Pirates Probable Starting Pitchers

Probable Pitchers: Robbie Ray (Giants) - 9-5, 2.85 ERA vs Andrew Heaney (Pirates) - 5-9, 4.89 ERA

The Giants will give the nod to Robbie Ray (9-5, 2.85 ERA), who is eyeing win No. 10 on the season, and the Pirates will counter with Andrew Heaney (5-9, 4.89 ERA). Ray's team is 14-9-0 against the spread this season in his starts. Ray's team has a record of 11-4 this season when he starts and they are the favorite on the moneyline. The Pirates have gone 6-11-0 ATS in Heaney's 17 starts that had a set spread. The Pirates have been the underdog on the moneyline in 13 of Heaney's starts this season, and they went 4-9 in those games.

Giants vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (52.2%)

Giants vs Pirates Moneyline

• The Giants vs Pirates moneyline has San Francisco as a -156 favorite, while Pittsburgh is a +132 underdog at home.

Giants vs Pirates Spread

• The Giants are 1.5-run road favorites on the runline against the Pirates. The Giants are +114 to cover, and the Pirates are -137.

Giants vs Pirates Over/Under

• A combined run total of 8 has been set for Giants-Pirates on Aug. 6, with the over at -105 and the under at -115.

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Giants vs Pirates Betting Trends

• The Giants have been victorious in 35, or 50.7%, of the 69 contests they have been chosen as favorites in this season.
• San Francisco has a record of 13-13 when favored by -156 or more this year.
• The Giants' games have gone over the total in 52 of their 113 opportunities.
• In 113 games with a line this season, the Giants have a mark of 47-66-0 against the spread.
• The Pirates have compiled a 31-41 record in games they were listed as the moneyline underdog (winning 43.1% of those games).
• In games it has played as a moneyline underdog with odds of +132 or longer, Pittsburgh has a 12-23 record (winning just 34.3% of its games).
• The Pirates have played in 105 games with a set over/under, and have combined with opponents to go over the total 42 times (42-60-3).
• The Pirates have covered 53.3% of their games this season, going 56-49-0 against the spread.

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.377) and total hits (109) this season. He's batting .256 batting average while slugging .460.
• Among qualified batters in baseball, his batting average ranks 86th, his on-base percentage ranks 12th, and he is 54th in slugging.
• Jung Hoo Lee has 25 doubles, nine triples, six home runs and 38 walks. He's batting .258 and slugging .409 with an on-base percentage of .327.
• Among qualified hitters, his batting average places him 79th, his on-base percentage 77th, and his slugging percentage 94th.
• Lee takes a four-game streak with at least one hit into this one. In his last five games he is hitting .400 with three doubles, a triple, a walk and three RBIs.
• Willy Adames has collected 96 base hits, an OBP of .317 and a slugging percentage of .405 this season.
• Heliot Ramos leads San Francisco with a slugging percentage of .421, fueled by 35 extra-base hits.
• Ramos heads into this game on a five-game hitting streak. During his last five outings he is hitting .348 with two walks and an RBI.

Pirates Player Leaders

• Oneil Cruz has 78 hits, a team-best for the Pirates. He's batting .211 and slugging .411 with an on-base percentage of .308.
• Including all qualifying hitters in the big leagues, he ranks 156th in batting average, 118th in on-base percentage and 91st in slugging percentage.
• Andrew McCutchen's .325 on-base percentage leads his team. He has a batting average of .246 while slugging .384.
• He is currently 112th in batting average, 81st in on-base percentage and 120th in slugging percentage among all qualified hitters.
• Bryan Reynolds has put up a team-best .373 slugging percentage.
• Isiah Kiner-Falefa has 14 doubles, two triples, a home run and 15 walks while batting .270.

Giants vs Pirates Head to Head

• 8/4/2025: 5-4 PIT (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/30/2025: 2-1 PIT (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/29/2025: 3-1 PIT (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 7/28/2025: 6-5 PIT (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/23/2024: 7-6 SF (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/22/2024: 9-5 SF (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/21/2024: 7-6 PIT (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/28/2024: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/27/2024: 4-3 PIT (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 4/26/2024: 3-0 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)

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