Ducks vs Sabres NHL Prediction, Odds, Picks, Best Bets for March 22

Sunday's slate in the NHL includes a matchup between the Buffalo Sabres and the Anaheim Ducks.

Before you place your bet on this game at FanDuel Sportsbook, here are the NHL moneyline insights you need to know.

Sabres vs Ducks Game Info

• Buffalo Sabres (44-20-6) vs. Anaheim Ducks (38-27-4)
• Date: Sunday, March 22, 2026
• Time: 8 p.m. ET
• Venue: Honda Center -- Anaheim, California
• Coverage: ESPN+

Sabres vs Ducks Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Sabres vs Ducks Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Sabres win (63.6%)

Sabres vs Ducks Puck Line

• The Sabres are favored by 1.5 goals. The Sabres are +210 to cover the spread, with the Ducks being -265.

Sabres vs Ducks Over/Under

• The over/under for Sabres-Ducks on March 22 is 6.5. The over is -132, and the under is +108.

Sabres vs Ducks Moneyline

• Looking at the moneyline for Sabres-Ducks, Buffalo is the favorite at -111, and Anaheim is -108 playing at home.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!