Diamondbacks vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 26

Odds updated as of 12:12 a.m.

The MLB's Wednesday slate includes the Arizona Diamondbacks facing the Chicago Cubs.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Cubs Game Info

• Arizona Diamondbacks (69-63) vs. Chicago Cubs (76-56)
• Date: Wednesday, August 26, 2026
• Time: 3:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and MARQ

Diamondbacks vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-108) | CHC: (-108)
• Spread: ARI: +1.5 (-178) | CHC: -1.5 (+146)
• Total: 8.5 -- Over: (-114) | Under: (-106)

Diamondbacks vs Cubs Probable Starting Pitchers

Probable Pitchers: Eduardo Rodríguez (Diamondbacks) - 13-4, 2.61 ERA vs Matthew Boyd (Cubs) - 8-2, 4.15 ERA

The Diamondbacks will give the nod to Eduardo Rodriguez (13-4) versus the Cubs and Matthew Boyd (8-2). Rodriguez and his team are 17-9-0 ATS this season when he starts. Rodriguez's team is 9-3 this season when he starts and they are the moneyline favorite. The Cubs have gone 9-6-0 against the spread when Boyd starts. The Cubs are 1-3 in Boyd's four starts this season that they were the underdog on the moneyline.

Diamondbacks vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (58.6%)

Diamondbacks vs Cubs Moneyline

• Arizona is a -108 favorite on the moneyline, while Chicago is a -108 underdog on the road.

Diamondbacks vs Cubs Spread

Diamondbacks vs Cubs Over/Under

• Diamondbacks versus Cubs, on Aug. 26, has an over/under of 8.5, with the over being -114 and the under -106.

Bet on Arizona Diamondbacks vs. Chicago Cubs on FanDuel today!

Diamondbacks vs Cubs Betting Trends

• The Diamondbacks have been favorites in 54 games this season and have come away with the win 32 times (59.3%) in those contests.
• Arizona has a record of 35-22 in contests when oddsmakers favor them by -108 or more on the moneyline.
• The Diamondbacks' games have gone over the total in 57 of their 131 opportunities.
• In 131 games with a line this season, the Diamondbacks have a mark of 70-61-0 against the spread.
• The Cubs are 21-18 in games they were the underdog on the moneyline (winning 53.8% of those games).
• Chicago has a 21-18 record (winning 53.8% of its games) when it has played as a moneyline underdog of -108 or longer.
• The Cubs have had an over/under set by bookmakers 127 times, and have combined with opponents to go over the total in 69 of those games (69-58-0).
• The Cubs have a 63-64-0 record against the spread this season (covering 49.6% of the time).

Diamondbacks Player Leaders

• Corbin Carroll leads Arizona in slugging percentage (.490) and total hits (120) this season. He's batting .251 with an on-base percentage of .349.
• Among qualified hitters in MLB, he ranks 77th in batting average, 46th in on-base percentage, and 23rd in slugging.
• Geraldo Perdomo has 18 doubles, six triples, nine home runs and 76 walks. He's batting .246 and slugging .370 with an on-base percentage of .354.
• He is 88th in batting average, 39th in on-base percentage and 116th in slugging among qualified hitters.
• Perdomo has picked up a hit in two straight games. During his last five outings he is batting .250 with a double, two walks and an RBI.
• Gabriel Moreno has 112 hits this season and a team-best OBP of .381.
• Nolan Arenado has been key for Arizona with 102 hits, an OBP of .317 plus a slugging percentage of .439.

Cubs Player Leaders

• Pete Crow-Armstrong has racked up 140 hits with a .376 on-base percentage and a .554 slugging percentage, all club-bests for the Cubs. He's batting .278.
• He is 27th in batting average, 11th in on-base percentage and second in slugging percentage among all qualified hitters in MLB.
• Alex Bregman is hitting .256 with 24 doubles, a triple, 19 home runs and 65 walks. He's slugging .418 with an on-base percentage of .345.
• His batting average ranks 68th among all qualified players, his on-base percentage ranks 51st, and he is 79th in slugging.
• Nico Hoerner has 27 doubles, a triple, seven home runs and 40 walks while batting .262.
• Seiya Suzuki is batting .269 with 25 doubles, 22 home runs and 61 walks.

Diamondbacks vs Cubs Head to Head

• 8/24/2026: 7-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +126)
• 5/3/2026: 8-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 11.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/2/2026: 2-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/1/2026: 6-5 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 4/19/2025: 6-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/18/2025: 13-11 CHC (Favorite: Diamondbacks, Spread: -1.5, Total: 11.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 3/30/2025: 10-6 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 3/29/2025: 4-3 CHC (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 3/28/2025: 8-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 3/27/2025: 10-6 CHC (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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