Cubs vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for May 23

Odds updated as of 2:11 p.m.

MLB action on Friday includes the Chicago Cubs facing the Cincinnati Reds.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this game.

Cubs vs Reds Game Info

• Chicago Cubs (30-20) vs. Cincinnati Reds (25-26)
• Date: Friday, May 23, 2025
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and MARQ

Cubs vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-116) | CIN: (-102)
• Spread: CHC: -1.5 (+140) | CIN: +1.5 (-170)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Cubs vs Reds Probable Starting Pitchers

Probable Pitchers: Matthew Boyd (Cubs) - 4-2, 2.98 ERA vs Hunter Greene (Reds) - 4-2, 2.36 ERA

The probable pitchers are Matthew Boyd (4-2) for the Cubs and Hunter Greene (4-2) for the Reds. Boyd's team is 3-6-0 against the spread in his starts this season. Boyd's team has been victorious in 80% of the games he's started as the moneyline favorite with a record of 4-1. The Reds have gone 3-4-0 ATS in Greene's seven starts with a set spread. The Reds are 2-2 in Greene's four starts this season that they were the underdog on the moneyline.

Cubs vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (51.8%)

Cubs vs Reds Moneyline

• Cincinnati is a -102 underdog on the moneyline, while Chicago is a -116 favorite on the road.

Cubs vs Reds Spread

• The Reds are +1.5 on the spread (-170 to cover), and Chicago is +140 to cover the runline.

Cubs vs Reds Over/Under

• The Cubs-Reds game on May 23 has been given an over/under of 8.5 runs. The over is set at -105 and the under at -115.

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Cubs vs Reds Betting Trends

• The Cubs have won in 20, or 71.4%, of the 28 contests they have been named as odds-on favorites in this year.
• This year Chicago has won 19 of 27 games when listed as at least -116 on the moneyline.
• The Cubs and their opponents have gone over in 30 of their 48 games with a total set by sportsbooks this season.
• The Cubs have an against the spread mark of 25-23-0 in 48 games with a line this season.
• The Reds are 12-14 in games they were listed as the moneyline underdog (winning 46.2% of those games).
• Cincinnati is 10-12 (winning 45.5% of its games) when playing as a moneyline underdog of -102 or longer.
• In the 49 games bookmakers have set an over/under for the Reds, they have combined with opponents to go over the total 18 times (18-29-2).
• The Reds have collected a 26-23-0 record ATS this season.

Cubs Player Leaders

• Kyle Tucker leads Chicago with an OBP of .387 this season while batting .278 with 35 walks and 38 runs scored. He has a slugging percentage of .552.
• He is 47th in batting average, 15th in on-base percentage, and 12th in slugging among qualified hitters in baseball.
• Tucker hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .389 with two home runs, five walks and two RBIs.
• Pete Crow-Armstrong has 55 hits to go with a slugging percentage of .553, both of which are tops among Chicago hitters this season. He's batting .279 with an on-base percentage of .313.
• His batting average ranks 44th among qualified players, his on-base percentage 101st, and his slugging percentage 11th.
• Seiya Suzuki has 47 hits this season and has a slash line of .253/.309/.527.
• Suzuki has recorded a hit in three straight games. During his last five outings he is hitting .316 with two doubles, a home run, three walks and six RBIs.
• Dansby Swanson has 10 home runs, 27 RBI and a batting average of .262 this season.
• Swanson has safely hit in seven straight games. During his last 10 games he is batting .351 with two home runs, four walks and five RBIs.

Reds Player Leaders

• Elly De La Cruz is hitting .242 with eight doubles, eight home runs and 20 walks. He's slugging .404 with an on-base percentage of .317.
• Including all the qualifying hitters in the big leagues, his batting average puts him 102nd, his on-base percentage ranks 96th, and he is 92nd in slugging.
• TJ Friedl is slugging .391 to lead his team. He has a batting average of .274 with an on-base percentage of .359.
• He is currently 58th in batting average, 43rd in on-base percentage and 105th in slugging percentage among all qualified batters.
• Gavin Lux has totaled 45 hits with a .377 on-base percentage, leading the Reds in both categories.
• Austin Hays is hitting .316 with six doubles, six home runs and seven walks.

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