Cubs vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 16

Odds updated as of 2:13 p.m.

The Chicago Cubs versus the Pittsburgh Pirates is on the MLB schedule for Saturday.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Cubs vs Pirates Game Info

• Chicago Cubs (68-53) vs. Pittsburgh Pirates (52-71)
• Date: Saturday, August 16, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: Fox Sports 1, MARQ, and SportsNet PT

Cubs vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-220) | PIT: (+184)
• Spread: CHC: -1.5 (-111) | PIT: +1.5 (-108)
• Total: 8.5 -- Over: (-118) | Under: (-104)

Cubs vs Pirates Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 8-5, 3.19 ERA vs Mike Burrows (Pirates) - 1-4, 4.66 ERA

The Cubs will call on Shota Imanaga (8-5) versus the Pirates and Mike Burrows (1-4). When Imanaga starts, his team is 8-8-0 against the spread this season. Imanaga's team has a record of 6-4 this season when he starts and they are the favorite on the moneyline. The Pirates have gone 7-6-0 ATS in Burrows' 13 starts that had a set spread. The Pirates have been the moneyline underdog in 11 of Burrows' starts this season, and they went 4-7 in those matchups.

Cubs vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (65%)

Cubs vs Pirates Moneyline

• The moneyline numbers for Cubs vs. Pirates reveal Chicago as the favorite (-220) and Pittsburgh as the underdog (+184) on the road.

Cubs vs Pirates Spread

• The Cubs are hosting the Pirates and are favored by 1.5 runs on the spread. The Cubs are -111 to cover the runline, with the Pirates being -108.

Cubs vs Pirates Over/Under

• An over/under of 8.5 has been set for Cubs-Pirates on Aug. 16, with the over being -118 and the under -104.

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Cubs vs Pirates Betting Trends

• The Cubs have come away with 51 wins in the 79 contests they have been listed as the favorites in this season.
• Oddsmakers have given Chicago the best odds of winning it has seen this season, with a -220 moneyline listed for this contest.
• The Cubs and their opponents have gone over the total this season in 56 of their 117 opportunities.
• The Cubs have posted a record of 55-62-0 against the spread this season.
• The Pirates are 33-46 in games they were the underdog on the moneyline (winning 41.8% of those games).
• Pittsburgh has yet to play a game with moneyline odds of +184 or longer.
• The Pirates have combined with opponents to hit the over on the total 46 times this season for a 46-65-4 record against the over/under.
• The Pirates have covered 52.2% of their games this season, going 60-55-0 against the spread.

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.376) this season, fueled by 114 hits. He has a .263 batting average and a slugging percentage of .454.
• Among qualifying hitters in baseball, he ranks 65th in batting average, 11th in on-base percentage, and 59th in slugging.
• Pete Crow-Armstrong leads Chicago with 119 hits. He is batting .259 this season and has 63 extra-base hits. He's also slugging .523 with an on-base percentage of .297.
• He is 77th in batting average, 141st in on-base percentage and 12th in slugging in the majors.
• Seiya Suzuki has 112 hits this season and has a slash line of .249/.319/.502.
• Nico Hoerner leads Chicago with a slugging percentage of .375, fueled by 26 extra-base hits.
• Hoerner heads into this matchup on a three-game hitting streak. In his last five games he is hitting .350 with .

Pirates Player Leaders

• Bryan Reynolds has totaled 111 hits with a .401 slugging percentage, both team-high stats for the Pirates. He's batting .244 and with an on-base percentage of .302.
• Including all qualified hitters in the big leagues, he is 113th in batting average, 129th in on-base percentage and 105th in slugging percentage.
• Andrew McCutchen's .330 on-base percentage leads his team. He has a batting average of .243 while slugging .377.
• Including all qualified hitters, he ranks 117th in batting average, 72nd in on-base percentage and 135th in slugging percentage.
• Isiah Kiner-Falefa is hitting .269 with 17 doubles, two triples, a home run and 16 walks.
• Tommy Pham has 12 doubles, a triple, five home runs and 32 walks while batting .263.

Cubs vs Pirates Head to Head

• 8/15/2025: 3-2 PIT (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/15/2025: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 6/14/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 6/13/2025: 2-1 PIT (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/12/2025: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 5/1/2025: 8-3 CHC (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/30/2025: 4-3 PIT (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/29/2025: 9-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/4/2024: 12-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/3/2024: 5-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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