Cubs vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for March 28

Odds updated as of 2:12 p.m.

The Saturday slate in MLB includes a matchup between the Chicago Cubs and the Washington Nationals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this game.

Cubs vs Nationals Game Info

• Chicago Cubs (0-1) vs. Washington Nationals (1-0)
• Date: Saturday, March 28, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Nationals.TV

Cubs vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-245) | WSH: (+200)
• Spread: CHC: -1.5 (-118) | WSH: +1.5 (-102)
• Total: 8.5 -- Over: (-120) | Under: (-102)

Cubs vs Nationals Probable Starting Pitchers

Probable Pitchers: Cade Horton (Cubs) - 0-0, 0.00 ERA vs Miles Mikolas (Nationals) - 0-0, 0.00 ERA

The Cubs will call on Cade Horton versus the Nationals and Miles Mikolas. Horton and his team were 11-11-0 ATS in his 22 appearances with a spread last season. Horton appeared in 16 games last season as the moneyline favorite and his team finished with a record of 12-4 in those contests. Last season Mikolas and his team went 14-17-0 against the spread in games he pitched. Mikolas and his team went 9-14 in the 23 games he pitched when they were the moneyline underdog a season ago.

Cubs vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (72.6%)

Cubs vs Nationals Moneyline

• Chicago is a -245 favorite on the moneyline, while Washington is a +200 underdog on the road.

Cubs vs Nationals Spread

• The Cubs are favored by 1.5 runs at home against the Nationals. The Cubs are -118 to cover the spread, while the Nationals are -102.

Cubs vs Nationals Over/Under

• The over/under for Cubs-Nationals on March 28 is 8.5. The over is -120, and the under is -102.

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Cubs vs Nationals Betting Trends

• The Cubs were chosen as favorites in 111 games last year and walked away with the win 72 times (64.9%) in those games.
• Last season Chicago came away with a win eight times in 10 chances when named as a favorite of at least -245 or shorter on the moneyline.
• The Cubs and their opponents hit the over in 77 of their 165 games with a total last season.
• The Nationals won 56 of the 131 games they were listed as the moneyline underdog last season (42.7%).
• Washington went 5-8 when playing as a moneyline underdog with odds of +200 or longer (38.5%).
• The Nationals combined with their opponents to hit the over on the total 83 times last season for an 83-66-7 record against the over/under.

Cubs Player Leaders

• Nico Hoerner finished with an OPS of .739 last season, fueled by a .345 OBP and a slugging percentage of .394.
• Pete Crow-Armstrong slashed .247/.287/.481 and finished with an OPS of .768.
• Michael Busch finished last season with 137 hits while batting .261.
• Ian Happ slashed .243/.342/.420 and finished with an OPS of .762.

Nationals Player Leaders

• C.J. Abrams hit .257 with 35 doubles, five triples, 19 home runs and 37 walks a season ago.
• James Wood had 153 hits and a .350 OBP while slugging .475.
• Luis Garcia had 28 doubles, a triple, 16 home runs and 27 walks while batting .252 last season.
• Daylen Lile hit .299 with 15 doubles, 11 triples, nine home runs and 21 walks.

Cubs vs Nationals Head to Head

• 3/26/2026: 10-4 WSH (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/7/2025: 6-3 WSH (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 9/6/2025: 2-1 WSH (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/5/2025: 11-5 CHC (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/5/2025: 7-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/4/2025: 2-0 WSH (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/3/2025: 8-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/21/2024: 5-1 WSH (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/20/2024: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/19/2024: 7-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)

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