Cubs vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 16

Odds updated as of 3:12 p.m.

The Chicago Cubs versus the St. Louis Cardinals is on the MLB schedule for Sunday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Cubs vs Cardinals Game Info

• Chicago Cubs (72-52) vs. St. Louis Cardinals (62-61)
• Date: Sunday, August 16, 2026
• Time: 3:15 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: ABC

Cubs vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-164) | STL: (+150)
• Spread: CHC: -1.5 (+125) | STL: +1.5 (-150)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Cubs vs Cardinals Probable Starting Pitchers

Probable Pitchers: Edward Cabrera (Cubs) - 5-4, 5.10 ERA vs Hunter Dobbins (Cardinals) - 2-3, 3.40 ERA

The Cubs will give the nod to Edward Cabrera (5-4) against the Cardinals and Hunter Dobbins (2-3). Cabrera and his team have a record of 7-5-0 against the spread when he starts. Cabrera's team has been victorious in 60% of the games he's started as the moneyline favorite with a record of 6-4. The Cardinals are 4-2-0 against the spread when Dobbins starts. The Cardinals are 2-4 in Dobbins' six starts this season that they were the moneyline underdog.

Cubs vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (62.4%)

Cubs vs Cardinals Moneyline

• The moneyline numbers for Cubs vs. Cardinals reveal Chicago as the favorite (-164) and St. Louis as the underdog (+150) on the road.

Cubs vs Cardinals Spread

• The Cardinals are at the Cubs, and are +1.5 on the runline. The Cardinals are +125 to cover the spread, and the Cubs are -150.

Cubs vs Cardinals Over/Under

• The over/under for the Cubs versus Cardinals contest on Aug. 16 has been set at 8.5, with -124 odds on the over and +102 odds on the under.

Bet on Chicago Cubs vs. St. Louis Cardinals on FanDuel today!

Cubs vs Cardinals Betting Trends

• The Cubs have been victorious in 46, or 58.2%, of the 79 contests they have been chosen as favorites in this season.
• Chicago has a record of 12-6 in contests when sportsbooks favor them by -164 or more on the moneyline.
• The Cubs' games have gone over the total in 64 of their 119 opportunities.
• The Cubs have an against the spread record of 60-59-0 in 119 games with a line this season.
• The Cardinals have been the moneyline underdog 82 total times this season. They've gone 39-43 in those games.
• In games it has played as a moneyline underdog with odds of +150 or longer, St. Louis has a 3-7 record (winning just 30% of its games).
• The Cardinals have played in 119 games with a set over/under, and have combined with their opponents to go over the total 47 times (47-65-7).
• The Cardinals have a 64-55-0 record against the spread this season.

Cubs Player Leaders

• Pete Crow-Armstrong has 130 hits and an OBP of .375 to go with a slugging percentage of .530. All three of those stats rank first among Chicago hitters this season. He has a .277 batting average, as well.
• Among the qualifying hitters in the majors, his batting average ranks 32nd, his on-base percentage ranks 11th, and he is 11th in slugging.
• Alex Bregman has 23 doubles, a triple, 16 home runs and 61 walks. He's batting .253 and slugging .405 with an on-base percentage of .344.
• His batting average is 76th among qualified players, his on-base percentage 53rd, and his slugging percentage 96th.
• Nico Hoerner has collected 125 base hits, an OBP of .319 and a slugging percentage of .361 this season.
• Seiya Suzuki is batting .274 with a .364 OBP and 73 RBI for Chicago this season.
• Suzuki has safely hit in two straight games. During his last five outings he is batting .368 with three doubles, two home runs, two walks and seven RBIs.

Cardinals Player Leaders

• Alec Burleson has racked up a team-high slugging percentage (.484) and leads the Cardinals in hits (132). He's batting .285 and with an on-base percentage of .353.
• Including all qualified hitters, he ranks 18th in batting average, while his on-base percentage is 43rd and he is 25th in slugging.
• Jordan Walker is hitting .280 with 24 doubles, 23 home runs and 40 walks. He's slugging .482 with an on-base percentage of .339.
• His batting average ranks 24th among all qualified players, his on-base percentage ranks 58th, and he is 29th in slugging.
• JJ Wetherholt is hitting .241 with 12 doubles, 16 home runs and 61 walks.
• Ivan Herrera paces his team with a .360 on-base percentage.

Cubs vs Cardinals Head to Head

• 8/15/2026: 8-4 STL (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +166)
• 8/14/2026: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -184, Underdog Moneyline: +170)
• 7/30/2026: 4-2 CHC (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 7/29/2026: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -125, Underdog Moneyline: -102)
• 7/28/2026: 10-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/5/2026: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 7/3/2026: 17-1 STL (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/31/2026: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/30/2026: 6-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/29/2026: 6-5 STL (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)

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