Cubs vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 14

Odds updated as of 2:12 p.m.

Friday's slate in the MLB includes a matchup between the Chicago Cubs and the St. Louis Cardinals.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Cardinals Game Info

• Chicago Cubs (71-51) vs. St. Louis Cardinals (61-60)
• Date: Friday, August 14, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: Apple TV+

Cubs vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-184) | STL: (+170)
• Spread: CHC: -1.5 (+112) | STL: +1.5 (-134)
• Total: 8 -- Over: (-108) | Under: (-112)

Cubs vs Cardinals Probable Starting Pitchers

Probable Pitchers: Clay Holmes (Cubs) - 4-5, 2.86 ERA vs Matthew Liberatore (Cardinals) - 5-9, 5.15 ERA

The Cubs will give the nod to Clay Holmes (4-5, 2.86 ERA), who is eyeing win No. 5 on the season, and the Cardinals will counter with Matthew Liberatore (5-9, 5.15 ERA). When Holmes starts, his team is 4-6-0 against the spread this season. Holmes' team is 4-2 this season when he starts and they are the moneyline favorite. The Cardinals have an 11-11-0 ATS record in Liberatore's 22 starts that had a set spread. The Cardinals have an 8-7 record in Liberatore's 15 starts this season when they were the underdog on the moneyline.

Cubs vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (66.8%)

Cubs vs Cardinals Moneyline

• Looking at the moneyline for Cubs-Cardinals, Chicago is the favorite at -184, and St. Louis is +170 playing on the road.

Cubs vs Cardinals Spread

• The Cardinals are at +1.5 on the runline against the Cubs. The Cardinals are -134 to cover the spread, and the Cubs are +112.

Cubs vs Cardinals Over/Under

• The over/under for Cubs-Cardinals on Aug. 14 is 8. The over is -108, and the under is -112.

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Cubs vs Cardinals Betting Trends

• The Cubs have been chosen as favorites in 77 games this year and have walked away with the win 45 times (58.4%) in those games.
• This year Chicago has won six of nine games when listed as at least -184 on the moneyline.
• The Cubs and their opponents have gone over in 63 of their 117 games with a total set by sportsbooks this season.
• The Cubs have posted a record of 59-58-0 against the spread this season.
• The Cardinals have put together a 38-42 record in games they were the underdog on the moneyline (winning 47.5% of those games).
• When playing as a moneyline underdog with odds of +170 or longer, St. Louis has a 2-3 record (winning 40% of its games).
• The Cardinals have had an over/under set by bookmakers 117 times, and have combined with opponents to go over the total in 46 of those games (46-64-7).
• The Cardinals have a 63-54-0 record against the spread this season (covering 53.8% of the time).

Cubs Player Leaders

• Pete Crow-Armstrong has 130 hits and an OBP of .381 to go with a slugging percentage of .539. All three of those stats are tops among Chicago hitters this season. He has a .281 batting average, as well.
• Among all qualifying batters in the majors, he is 25th in batting average, ninth in on-base percentage, and 10th in slugging.
• Alex Bregman is batting .254 with 23 doubles, a triple, 16 home runs and 60 walks, while slugging .409 with an on-base percentage of .345.
• He is 74th in batting average, 51st in on-base percentage and 91st in slugging in the major leagues.
• Nico Hoerner is batting .262 with a .365 slugging percentage and 56 RBI this year.
• Hoerner heads into this game with four games in a row with at least one hit. During his last five outings he is batting .300 with two doubles, a walk and two RBIs.
• Seiya Suzuki has 20 home runs, 70 RBI and a batting average of .271 this season.

Cardinals Player Leaders

• Alec Burleson has racked up a team-best .482 slugging percentage. He's batting .287 with an on-base percentage of .354.
• He ranks 16th in batting average, 39th in on-base percentage and 25th in slugging percentage among all qualified batters in the majors.
• Burleson hopes to build on a four-game hitting streak in this matchup. In his last five games he is batting .333 with two doubles, a home run, three walks and seven RBIs.
• Jordan Walker's 129 hits lead his team. He has a batting average of .284 while slugging .489 with an on-base percentage of .343.
• Including all qualified players, he ranks 21st in batting average, 53rd in on-base percentage and 18th in slugging percentage.
• JJ Wetherholt is hitting .245 with 12 doubles, 16 home runs and 60 walks.
• Ivan Herrera leads his team with a .359 on-base percentage.

Cubs vs Cardinals Head to Head

• 7/30/2026: 4-2 CHC (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 7/29/2026: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -125, Underdog Moneyline: -102)
• 7/28/2026: 10-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/5/2026: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 7/3/2026: 17-1 STL (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/31/2026: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/30/2026: 6-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/29/2026: 6-5 STL (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/28/2025: 2-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/27/2025: 7-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -178, Underdog Moneyline: +150)

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