Cardinals vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 18

Odds updated as of 2:12 a.m.

The St. Louis Cardinals will face the Cincinnati Reds in MLB action on Tuesday.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cardinals vs Reds Game Info

• St. Louis Cardinals (64-62) vs. Cincinnati Reds (60-65)
• Date: Tuesday, August 18, 2026
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Cardinals.TV

Cardinals vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-120) | CIN: (+102)
• Spread: STL: -1.5 (+134) | CIN: +1.5 (-162)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Cardinals vs Reds Probable Starting Pitchers

Probable Pitchers: Kyle Leahy (Cardinals) - 9-4, 3.38 ERA vs Andrew Abbott (Reds) - 6-7, 4.13 ERA

This contest's pitching matchup is set, as the Cardinals will send Kyle Leahy (9-4) to the mound, while Andrew Abbott (6-7) will get the nod for the Reds. Leahy and his team have a record of 10-11-0 against the spread when he starts. Leahy's team has been victorious in 42.9% of the games he's started as the moneyline favorite with a record of 3-4. The Reds have gone 12-13-0 against the spread when Abbott starts. The Reds have been the moneyline underdog in 20 of Abbott's starts this season, and they went 9-11 in those matchups.

Cardinals vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (57.3%)

Cardinals vs Reds Moneyline

• St. Louis is the favorite, -120 on the moneyline, while Cincinnati is a +102 underdog despite being at home.

Cardinals vs Reds Spread

• The Reds are at +1.5 on the runline against the Cardinals. The Reds are -162 to cover the spread, and the Cardinals are +134.

Cardinals vs Reds Over/Under

• An over/under of 8.5 has been set for Cardinals-Reds on Aug. 18, with the over being -124 and the under +102.

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Cardinals vs Reds Betting Trends

• The Cardinals have come away with 21 wins in the 38 contests they have been listed as the favorites in this season.
• This season St. Louis has been victorious 13 times in 22 chances when named as a favorite of at least -120 on the moneyline.
• The Cardinals and their opponents have gone over in 49 of their 122 games with a total set by sportsbooks this season.
• In 122 games with a line this season, the Cardinals have a mark of 65-57-0 against the spread.
• The Reds have been the moneyline underdog 81 total times this season. They've gone 39-42 in those games.
• Cincinnati has a 27-36 record (winning 42.9% of its games) when it has played as a moneyline underdog of +102 or longer.
• The Reds have combined with opponents to go over the total 64 times this season for a 64-56-2 record against the over/under.
• The Reds have a 65-57-0 record ATS this season.

Cardinals Player Leaders

• Alec Burleson leads St. Louis in slugging percentage (.493) thanks to 54 extra-base hits. He has a .289 batting average and an on-base percentage of .355.
• Among all qualified hitters in baseball, his batting average ranks 14th, his on-base percentage ranks 39th, and he is 21st in slugging.
• Burleson will look for his fifth straight game with a hit in this contest. During his last five outings he is batting .333 with two doubles, two home runs, a walk and eight RBIs.
• Jordan Walker leads St. Louis with 137 hits. He is batting .289 this season and has 52 extra-base hits. He's also slugging .500 with an on-base percentage of .347.
• He is 14th in batting average, 50th in on-base percentage and 15th in slugging in MLB.
• Walker heads into this game looking to extend his three-game hit streak. During his last five outings he is batting .400 with four doubles, a home run, a walk and four RBIs.
• JJ Wetherholt has collected 113 base hits, an OBP of .349 and a slugging percentage of .375 this season.
• Ivan Herrera leads St. Louis in OBP (.363) this season, fueled by 116 hits.

Reds Player Leaders

• Sal Stewart has accumulated a team-high slugging percentage (.473) and leads the Reds in hits (123). He's batting .258 and with an on-base percentage of .333.
• Including all qualified players, he is 70th in batting average, while his on-base percentage is 71st and he is 32nd in slugging.
• Elly De La Cruz has a .344 on-base percentage to lead his team. He has a batting average of .261 while slugging .472.
• Including all qualified players, he is 62nd in batting average, 54th in on-base percentage and 34th in slugging percentage.
• JJ Bleday is batting .223 with 13 doubles, a triple, 20 home runs and 57 walks.
• Tyler Stephenson is hitting .248 with 16 doubles, 12 home runs and 37 walks.

Cardinals vs Reds Head to Head

• 8/17/2026: 6-5 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: +108)
• 8/17/2026: 2-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: +100)
• 7/26/2026: 5-3 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/25/2026: 7-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/24/2026: 4-2 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/7/2026: 5-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/6/2026: 6-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/5/2026: 10-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/23/2026: 7-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/23/2026: 8-1 STL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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