Cardinals vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for March 28

Odds updated as of 2:12 p.m.

The MLB's Saturday slate includes the Tampa Bay Rays facing the St. Louis Cardinals.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Rays vs Cardinals Game Info

• Tampa Bay Rays (0-1) vs. St. Louis Cardinals (1-0)
• Date: Saturday, March 28, 2026
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and Rays.TV

Rays vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-112) | STL: (-104)
• Spread: TB: -1.5 (+146) | STL: +1.5 (-178)
• Total: 7.5 -- Over: (+100) | Under: (-122)

Rays vs Cardinals Probable Starting Pitchers

Probable Pitchers: Joe Boyle (Rays) - 0-0, 0.00 ERA vs Michael McGreevy (Cardinals) - 0-0, 0.00 ERA

The Rays will look to Joe Boyle versus the Cardinals and Michael McGreevy. Boyle and his team were 3-6-0 ATS in games he pitched last year. Boyle did not pitch as the moneyline favorite in any games last season. Last season McGreevy and his team went 9-7-0 against the spread when he pitched. McGreevy and his team went 7-3 in games he pitched when they were the underdog on the moneyline a season ago.

Rays vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (50.2%)

Rays vs Cardinals Moneyline

• St. Louis is the underdog, -104 on the moneyline, while Tampa Bay is a -112 favorite despite being on the road.

Rays vs Cardinals Spread

• The Cardinals are at +1.5 on the runline against the Rays. The Cardinals are -178 to cover the spread, and the Rays are +146.

Rays vs Cardinals Over/Under

• Rays versus Cardinals, on March 28, has an over/under of 7.5, with the over being +100 and the under -122.

Bet on Tampa Bay Rays vs. St. Louis Cardinals on FanDuel today!

Rays vs Cardinals Betting Trends

• The Rays were favorites in 72 games last season and came away with the win 39 times (54.2%) in those contests.
• Last year, Tampa Bay won 39 of 71 games when listed as at least -112 on the moneyline.
• The Rays and their opponents hit the over in 69 of their 157 games with a total last season.
• The Cardinals compiled a 43-47 record in games last season when they were listed as the moneyline underdog (winning 47.8% of those games).
• When playing as a moneyline underdog with odds of -104 or longer last year, St. Louis went 36-45 (44.4%).
• The Cardinals played in 156 games with a set over/under last season, and combined with their opponents to go over the total 80 times (80-71-5).

Rays Player Leaders

• Last season, Junior Caminero had 159 base hits, batting .264 with 73 extra-base hits.
• Yandy Diaz slashed .300/.366/.482 and finished with an OPS of .848.
• Chandler Simpson ended his last campaign with 122 hits, an OBP of .326, plus a slugging percentage of .345.
• Cedric Mullins slashed .216/.299/.391 and finished with an OPS of .690.

Cardinals Player Leaders

• Alec Burleson put up an on-base percentage of .343, a slugging percentage of .459, and had 144 hits last season.
• Ivan Herrera hit .284 with 13 doubles, 19 home runs and 43 walks.
• Masyn Winn hit .253 with 27 doubles, nine home runs and 34 walks a season ago.
• Victor Scott II hit .216 with 15 doubles, a triple, five home runs and 42 walks.

Rays vs Cardinals Head to Head

• 3/26/2026: 9-7 STL (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/22/2025: 10-6 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 7-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/8/2024: 6-4 TB (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/7/2024: 5-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/6/2024: 4-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/10/2023: 5-2 STL (Favorite: Rays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 8/9/2023: 6-4 STL (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/8/2023: 4-2 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/9/2022: 2-1 TB (Favorite: Rays, Spread: -1.5, Total: 6.5, Favorite Moneyline: -168, Underdog Moneyline: +142)

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