Brewers vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 8:14 p.m.

In MLB action on Friday, the Milwaukee Brewers take on the San Diego Padres.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Padres Game Info

• Milwaukee Brewers (34-29) vs. San Diego Padres (35-26)
• Date: Friday, June 6, 2025
• Time: 8:10 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and SDPA

Brewers vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-124) | SD: (+106)
• Spread: MIL: -1.5 (+164) | SD: +1.5 (-200)
• Total: 8.5 -- Over: (-106) | Under: (-114)

Brewers vs Padres Probable Starting Pitchers

Probable Pitchers: Chad Patrick (Brewers) - 3-4, 2.97 ERA vs Randy Vasquez (Padres) - 3-4, 3.99 ERA

The Brewers will look to Chad Patrick (3-4) versus the Padres and Randy Vasquez (3-4). Patrick and his team have a record of 6-5-0 against the spread when he starts. Patrick's team has been victorious in 50% of the games he's started as the moneyline favorite with a record of 3-3. The Padres are 6-5-0 ATS in Vasquez's 11 starts that had a set spread. The Padres are 2-5 in Vasquez's seven starts this season that they were the moneyline underdog.

Brewers vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (53.7%)

Brewers vs Padres Moneyline

• The moneyline numbers for Brewers vs. Padres reveal Milwaukee as the favorite (-124) and San Diego as the underdog (+106) on the road.

Brewers vs Padres Spread

• The Brewers are hosting the Padres and are favored by 1.5 runs on the spread. The Brewers are +164 to cover the runline, with the Padres being -200.

Brewers vs Padres Over/Under

• The Brewers-Padres contest on June 6 has been given an over/under of 8.5 runs. The over is set at -106 and the under at -114.

Bet on Milwaukee Brewers vs. San Diego Padres on FanDuel today!

Brewers vs Padres Betting Trends

• The Brewers have been chosen as favorites in 30 games this year and have walked away with the win 21 times (70%) in those games.
• This year Milwaukee has won 14 of 17 games when listed as at least -124 on the moneyline.
• The Brewers and their opponents have hit the over in 25 of their 62 games with a total set by oddsmakers this season.
• The Brewers are 34-28-0 against the spread in their 62 games with a line set by sportsbooks this season.
• The Padres have won 12 of the 24 games they were the underdog on the moneyline this season (50%).
• San Diego has gone 9-8 when playing as a moneyline underdog with odds of +106 or longer (52.9%).
• The Padres have played in 60 games with a set over/under, and have combined with their opponents to go over the total 25 times (25-33-2).
• The Padres have a 31-29-0 record ATS this season (covering 51.7% of the time).

Brewers Player Leaders

• Jackson Chourio leads Milwaukee in slugging percentage (.446) thanks to 29 extra-base hits. He has a .260 batting average and an on-base percentage of .286.
• Among the qualifying hitters in MLB, his batting average ranks 76th, his on-base percentage ranks 145th, and he is 60th in slugging.
• Christian Yelich has five doubles, 13 home runs and 24 walks. He's batting .237 and slugging .430 with an on-base percentage of .316.
• Among qualifying hitters, his batting average ranks him 117th, his on-base percentage 97th, and his slugging percentage 72nd.
• Yelich has picked up a hit in three straight games. During his last five outings he is batting .421 with a home run and three RBIs.
• Brice Turang is batting .277 with a .366 slugging percentage and 25 RBI this year.
• Turang takes a two-game hitting streak into this game. During his last five outings he is hitting .375 with two doubles, four walks and three RBIs.
• Sal Frelick is batting .291 with a .352 OBP and 21 RBI for Milwaukee this season.

Padres Player Leaders

• Manny Machado has totaled 72 hits with a .382 on-base percentage and a .498 slugging percentage, all club-bests for the Padres. He's batting .317.
• Including all the qualified players in the big leagues, his batting average ranks 10th, his on-base percentage is 17th, and he is 25th in slugging.
• Machado takes a three-game hitting streak into this matchup. In his last five games he is batting .421 with two home runs, two walks and six RBIs.
• Fernando Tatis Jr. is hitting .268 with eight doubles, a triple, 13 home runs and 25 walks. He's slugging .477 with an on-base percentage of .340.
• Including all qualified hitters, his batting average places him 63rd, his on-base percentage is 61st, and he is 43rd in slugging.
• Luis Arraez has 12 doubles, three triples, three home runs and 11 walks while hitting .282.
• Gavin Sheets is batting .263 with seven doubles, a triple, 11 home runs and 14 walks.

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