Brewers vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 5:12 p.m.

The MLB's Friday slate includes the Milwaukee Brewers facing the San Diego Padres.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Padres Game Info

• Milwaukee Brewers (34-29) vs. San Diego Padres (35-26)
• Date: Friday, June 6, 2025
• Time: 8:10 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and SDPA

Brewers vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-124) | SD: (+106)
• Spread: MIL: -1.5 (+158) | SD: +1.5 (-192)
• Total: 8 -- Over: (-115) | Under: (-105)

Brewers vs Padres Probable Starting Pitchers

Probable Pitchers: Chad Patrick (Brewers) - 3-4, 2.97 ERA vs Randy Vasquez (Padres) - 3-4, 3.99 ERA

The Brewers will call on Chad Patrick (3-4) against the Padres and Randy Vasquez (3-4). Patrick and his team have a record of 6-5-0 against the spread when he starts. When Patrick starts a game and his team is the favorite on the moneyline, they have a record of 3-3. The Padres are 6-5-0 against the spread when Vasquez starts. The Padres have been the underdog on the moneyline in seven of Vasquez's starts this season, and they went 2-5 in those matchups.

Brewers vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (50.4%)

Brewers vs Padres Moneyline

• San Diego is a +106 underdog on the moneyline, while Milwaukee is a -124 favorite at home.

Brewers vs Padres Spread

• The Padres are +1.5 on the spread (-192 to cover), and Milwaukee is +158 to cover the runline.

Brewers vs Padres Over/Under

• The over/under for the Brewers versus Padres contest on June 6 has been set at 8, with -115 odds on the over and -105 odds on the under.

Bet on Milwaukee Brewers vs. San Diego Padres on FanDuel today!

Brewers vs Padres Betting Trends

• The Brewers have been favorites in 30 games this season and have come away with the win 21 times (70%) in those contests.
• This year Milwaukee has won 14 of 17 games when listed as at least -124 on the moneyline.
• The Brewers and their opponents have hit the over in 25 of their 62 games with a total set by oddsmakers this season.
• The Brewers have an against the spread record of 34-28-0 in 62 games with a line this season.
• The Padres have won 50% of the games this season they were the underdog on the moneyline (12-12).
• San Diego has a 9-8 record (winning 52.9% of its games) when playing as a moneyline underdog of +106 or longer.
• The Padres have had an over/under set by bookmakers 60 times, and have combined with opponents to go over the total in 25 of those games (25-33-2).
• The Padres have a 31-29-0 record ATS this season.

Brewers Player Leaders

• Jackson Chourio has an OPS of .732, fueled by an OBP of .286 and a team-best slugging percentage of .446 this season. He has a .260 batting average.
• He ranks 76th in batting average, 145th in on-base percentage, and 60th in slugging among all qualified hitters in MLB.
• Christian Yelich has five doubles, 13 home runs and 24 walks. He's batting .237 and slugging .430 with an on-base percentage of .316.
• His batting average ranks 117th among qualified players, his on-base percentage 97th, and his slugging percentage 72nd.
• Yelich has picked up a hit in three straight games. In his last five games he is hitting .421 with a home run and three RBIs.
• Brice Turang has 62 hits this season and has a slash line of .277/.358/.366.
• Turang takes a two-game hitting streak into this game. In his last five games he is hitting .375 with two doubles, four walks and three RBIs.
• Sal Frelick is batting .291 with a .352 OBP and 21 RBI for Milwaukee this season.

Padres Player Leaders

• Manny Machado has 72 hits with a .382 on-base percentage and a .498 slugging percentage, all club-highs for the Padres. He's batting .317.
• Including all the qualifying hitters in the big leagues, his batting average ranks 10th, his on-base percentage is 17th, and he is 25th in slugging.
• Machado hopes to build on a three-game hitting streak in this matchup. In his last five games he is hitting .421 with two home runs, two walks and six RBIs.
• Fernando Tatis Jr. is hitting .268 with eight doubles, a triple, 13 home runs and 25 walks. He's slugging .477 with an on-base percentage of .340.
• Including all qualifying players, he is 63rd in batting average, 61st in on-base percentage and 43rd in slugging percentage.
• Luis Arraez is batting .282 with 12 doubles, three triples, three home runs and 11 walks.
• Gavin Sheets is hitting .263 with seven doubles, a triple, 11 home runs and 14 walks.

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