Astros vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 10

Odds updated as of 7:16 p.m.

MLB action on Tuesday includes the Houston Astros facing the Chicago White Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs White Sox Game Info

• Houston Astros (36-29) vs. Chicago White Sox (22-44)
• Date: Tuesday, June 10, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and CHSN

Astros vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-174) | CHW: (+146)
• Spread: HOU: -1.5 (+125) | CHW: +1.5 (-150)
• Total: 7.5 -- Over: (-114) | Under: (-106)

Astros vs White Sox Probable Starting Pitchers

Probable Pitchers: Lance McCullers (Astros) - 1-1, 4.44 ERA vs Shane Smith (White Sox) - 2-3, 2.45 ERA

The probable pitchers are Lance McCullers (1-1) for the Astros and Shane Smith (2-3) for the White Sox. McCullers and his team have a record of 4-2-0 against the spread when he starts. McCullers' team has won 33.3% of his starts when they are favored on the moneyline (1-2). The White Sox are 6-6-0 against the spread when Smith starts. The White Sox have a 3-8 record in Smith's 11 starts this season when they were the underdog on the moneyline.

Astros vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (65.8%)

Astros vs White Sox Moneyline

• Houston is a -174 favorite on the moneyline, while Chicago is a +146 underdog on the road.

Astros vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Astros. The White Sox are -150 to cover the spread, and the Astros are +125.

Astros vs White Sox Over/Under

• The over/under for the Astros versus White Sox contest on June 10 has been set at 7.5, with -114 odds on the over and -106 odds on the under.

Bet on Houston Astros vs. Chicago White Sox on FanDuel today!

Astros vs White Sox Betting Trends

• The Astros have come away with 24 wins in the 43 contests they have been listed as the favorites in this season.
• Houston has a record of 3-1 in contests when bookmakers favor them by -174 or more on the moneyline.
• The Astros' games have gone over the total in 25 of their 64 opportunities.
• The Astros have posted a record of 34-30-0 against the spread this season.
• The White Sox have gone 20-42 in games they were the underdog on the moneyline (winning 32.3% of those games).
• Chicago has gone 9-29 when it has played as a moneyline underdog with odds of +146 or longer (23.7%).
• The White Sox have played in 63 games with a set over/under, and have combined with their opponents to go over the total 30 times (30-30-3).
• The White Sox have gone 35-28-0 against the spread this season.

Astros Player Leaders

• Jeremy Pena has 79 hits and an OBP of .373 to go with a slugging percentage of .480. All three of those stats lead Houston hitters this season. He has a .316 batting average, as well.
• Among qualified hitters, he is eighth in batting average, his on-base percentage ranks 24th, and he is 39th in slugging.
• Isaac Paredes has seven doubles, a triple, 14 home runs and 34 walks. He's batting .249 and slugging .461 with an on-base percentage of .348.
• He is 97th in batting average, 52nd in on-base percentage and 49th in slugging in MLB.
• Jose Altuve has 64 hits this season and has a slash line of .261/.306/.396.
• Jake Meyers has been key for Houston with 60 hits, an OBP of .361 plus a slugging percentage of .412.
• Meyers enters this game on a three-game hitting streak. In his last five games he is batting .389 with a double and three walks.

White Sox Player Leaders

• Miguel Vargas has an on-base percentage of .319 and has 54 hits, both team-high numbers for the White Sox. He's batting .237 and slugging .421.
• Including all the qualifying hitters in the majors, his batting average is 118th, his on-base percentage is 98th, and he is 84th in slugging.
• Chase Meidroth is hitting .299 with five doubles, two home runs and 21 walks. He's slugging .370 with an on-base percentage of .383.
• Andrew Benintendi is batting .246 with six doubles, a triple, six home runs and 14 walks.
• Luis Robert is hitting .177 with six doubles, five home runs and 25 walks.

Astros vs White Sox Head to Head

• 5/4/2025: 5-4 CHW (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 5/3/2025: 8-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 5/2/2025: 7-3 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/18/2024: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 8/17/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 8/16/2024: 5-4 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 6/20/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 6/19/2024: 4-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/18/2024: 2-0 CHW (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/14/2023: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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