Astros vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 3

Odds updated as of 1:11 p.m.

The MLB schedule on Saturday includes the Houston Astros facing the Chicago White Sox.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Astros vs White Sox Game Info

• Houston Astros (16-15) vs. Chicago White Sox (9-23)
• Date: Saturday, May 3, 2025
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and SCHN

Astros vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-235) | CHW: (+194)
• Spread: HOU: -1.5 (-134) | CHW: +1.5 (+112)
• Total: 7.5 -- Over: (-106) | Under: (-114)

Astros vs White Sox Probable Starting Pitchers

Probable Pitchers: Hunter Brown (Astros) - 4-1, 1.22 ERA vs Davis Martin (White Sox) - 1-3, 3.24 ERA

The Astros will call on Hunter Brown (4-1) versus the White Sox and Davis Martin (1-3). When Brown starts, his team is 4-2-0 against the spread this season. Brown's team has been victorious in 60% of the games he's started as the moneyline favorite with a record of 3-2. The White Sox have a 2-3-0 record against the spread in Martin's starts. The White Sox have a 1-4 record in Martin's five starts this season when they were the moneyline underdog.

Astros vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (66.4%)

Astros vs White Sox Moneyline

• Chicago is the underdog, +194 on the moneyline, while Houston is a -235 favorite despite being on the road.

Astros vs White Sox Spread

• The White Sox are +1.5 on the spread (+112 to cover), and Houston is -134 to cover the runline.

Astros vs White Sox Over/Under

• The over/under for the Astros versus White Sox contest on May 3 has been set at 7.5, with -106 odds on the over and -114 odds on the under.

Bet on Houston Astros vs. Chicago White Sox on FanDuel today!

Astros vs White Sox Betting Trends

• The Astros have come away with 11 wins in the 22 contests they have been listed as the favorites in this season.
• Houston has played as a favorite of -235 or more just one time this year and came away with a loss in that game.
• The Astros' games have gone over the total in 13 of their 31 opportunities.
• In 31 games with a line this season, the Astros have a mark of 17-14-0 against the spread.
• The White Sox have a 9-23 record in games they were the underdog on the moneyline (winning 28.1% of those games).
• Chicago has a record of 2-8 in games it has played as a moneyline underdog with odds of +194 or longer (20%).
• The White Sox have combined with opponents to hit the over on the total 15 times this season for a 15-15-2 record against the over/under.
• The White Sox have collected a 17-15-0 record ATS this season (covering 53.1% of the time).

Astros Player Leaders

• Jeremy Pena has 32 hits, which is best among Houston hitters this season, while batting .278 with nine extra-base hits. He has an on-base percentage of .349 and a slugging percentage of .426.
• Among all qualified batters in the majors, he ranks 41st in batting average, 52nd in on-base percentage, and 66th in slugging.
• Pena hopes to build on a six-game hitting streak in this matchup. In his last 10 outings he is batting .385 with two doubles, a home run, three walks and five RBI.
• Isaac Paredes leads Houston in OBP (.358) this season, fueled by 29 hits. He's batting .252 while slugging .400.
• Among qualifiers, he ranks 77th in batting average, 46th in on-base percentage and 91st in slugging percentage.
• Paredes enters this matchup looking to extend his four-game hit streak. In his last five games he is batting .235 with a triple, five walks and an RBI.
• Jose Altuve has an OPS of .712, fueled by an OBP of .318 and a team-best slugging percentage of .393 this season.
• Altuve has picked up a hit in two games in a row. During his last five outings he is batting .211 with a double, a home run, four walks and five RBI.
• Yordan Alvarez has three home runs, 18 RBI and a batting average of .210 this season.

White Sox Player Leaders

• Luis Robert has totaled 20 hits with a .310 on-base percentage, leading the White Sox in both categories. He's batting .189 and slugging .358.
• Including all the qualifying players in the big leagues, his batting average is 150th, his on-base percentage ranks 96th, and he is 117th in slugging.
• Robert brings a seven-game hitting streak into this matchup. During his last 10 games he is batting .270 with two doubles, three home runs, seven walks and eight RBI.
• Miguel Vargas paces his team with a .310 on-base percentage. He has a batting average of .216 while slugging .324.
• His batting average is 121st among all qualified players, his on-base percentage ranks 96th, and he is 139th in slugging.
• Andrew Benintendi is batting .231 with five home runs and eight walks.
• Brooks Baldwin is hitting .242 with five doubles, three home runs and four walks.

Astros vs White Sox Head to Head

• 5/2/2025: 7-3 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/18/2024: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 8/17/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -375, Underdog Moneyline: +300)
• 8/16/2024: 5-4 CHW (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 6/20/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 6/19/2024: 4-1 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/18/2024: 2-0 CHW (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/14/2023: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/13/2023: 3-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/12/2023: 5-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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