Twins vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for May 11

Odds updated as of 1:11 p.m.

The Minnesota Twins are among the MLB teams busy on Sunday, versus the San Francisco Giants.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Twins vs Giants Game Info

• Minnesota Twins (20-20) vs. San Francisco Giants (24-16)
• Date: Sunday, May 11, 2025
• Time: 2:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and NBCS-BA

Twins vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-158) | SF: (+134)
• Spread: MIN: -1.5 (+134) | SF: +1.5 (-162)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Twins vs Giants Probable Starting Pitchers

Probable Pitchers: Pablo Lopez (Twins) - 3-2, 2.18 ERA vs Landen Roupp (Giants) - 2-3, 4.89 ERA

The Twins will look to Pablo Lopez (3-2) versus the Giants and Landen Roupp (2-3). Lopez's team is 4-2-0 against the spread this season in his starts. Lopez's team is 3-2 this season when he starts and they are the moneyline favorite. The Giants have a 2-5-0 ATS record in Roupp's seven starts that had a set spread. The Giants are 2-2 in Roupp's four starts this season that they were the moneyline underdog.

Twins vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (55.3%)

Twins vs Giants Moneyline

• Minnesota is the favorite, -158 on the moneyline, while San Francisco is a +134 underdog on the road.

Twins vs Giants Spread

• The Giants are +1.5 on the run line against the Twins. The Giants are -162 to cover, and the Twins are +134.

Twins vs Giants Over/Under

• The over/under for Twins-Giants on May 11 is 8.5. The over is -105, and the under is -115.

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Twins vs Giants Betting Trends

• The Twins have been victorious in 14, or 53.8%, of the 26 contests they have been chosen as favorites in this season.
• Minnesota has a record of 8-2 when favored by -158 or more this year.
• The Twins and their opponents have hit the over in 13 of their 39 games with a total set by oddsmakers this season.
• The Twins have posted a record of 21-18-0 against the spread this season.
• The Giants have been the underdog on the moneyline 15 total times this season. They've gone 8-7 in those games.
• When it has played as a moneyline underdog with odds of +134 or longer, San Francisco has gone 2-3 (40%).
• The Giants have had an over/under set by bookmakers 40 times, and have combined with opponents to go over the total in 22 of those games (22-17-1).
• The Giants have a 19-21-0 record ATS this season (covering 47.5% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota with 39 hits and a team-best slugging percentage of .535. He's batting .271 with an on-base percentage of .314.
• Among all qualified batters in MLB, his batting average ranks 53rd, his on-base percentage ranks 97th, and he is 15th in slugging.
• Ty France has a slash line of .269/.335/.386 this season and a team-best OPS of .722.
• He ranks 55th in batting average, 74th in on-base percentage and 103rd in slugging among qualifying hitters.
• Trevor Larnach has 33 hits this season and has a slash line of .232/.313/.380.
• Larnach takes a three-game hitting streak into this matchup. During his last five outings he is batting .250 with a double, two home runs and four RBIs.
• Harrison Bader is batting .290 with a .383 OBP and 16 RBI for Minnesota this season.
• Bader takes a two-game hitting streak into this game. During his last five outings he is batting .400 with two doubles, a home run, four walks and three RBIs.

Giants Player Leaders

• Jung Hoo Lee has accumulated a team-high slugging percentage (.467) and paces the Giants in hits (43). He's batting .287 and with an on-base percentage of .337.
• Including all the qualifying hitters in MLB, he ranks 34th in batting average, 70th in on-base percentage and 46th in slugging percentage.
• Matt Chapman is batting .217 with five doubles, eight home runs and 29 walks. He's slugging .428 with an on-base percentage of .353.
• Including all qualifying players, his batting average puts him 133rd, his on-base percentage is 49th, and he is 66th in slugging.
• Wilmer Flores has two doubles, seven home runs and nine walks while hitting .245.
• Heliot Ramos is batting .268 with 10 doubles, six home runs and 12 walks.

Twins vs Giants Head to Head

• 5/10/2025: 2-1 MIN (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/9/2025: 3-1 MIN (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/14/2024: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/13/2024: 4-2 MIN (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/12/2024: 7-1 SF (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/24/2023: 7-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 5/23/2023: 4-3 SF (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/22/2023: 4-1 SF (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 8/28/2022: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/27/2022: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)

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