Tigers vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 2:12 a.m.

The MLB's Monday slate includes the Detroit Tigers facing the Boston Red Sox.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Tigers vs Red Sox Game Info

• Detroit Tigers (18-17) vs. Boston Red Sox (13-21)
• Date: Monday, May 4, 2026
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: DSN and NESN

Tigers vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-230) | BOS: (+190)
• Spread: DET: -1.5 (-102) | BOS: +1.5 (-118)
• Total: 7 -- Over: (+100) | Under: (-122)

Tigers vs Red Sox Probable Starting Pitchers

Probable Pitchers: Tarik Skubal (Tigers) - 3-2, 2.70 ERA vs Payton Tolle (Red Sox) - 0-1, 3.37 ERA

The probable starters are Tarik Skubal (3-2) for the Tigers and Payton Tolle (0-1) for the Red Sox. Skubal and his team have a record of 3-4-0 against the spread when he starts. Skubal's team has a record of 4-3 this season when he starts and they are the favorite on the moneyline. Tolle has started two games with set spreads, and the Red Sox failed to cover in both opportunities. The Red Sox were named the moneyline underdog for two Tolle starts this season -- they lost both.

Tigers vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (66.3%)

Tigers vs Red Sox Moneyline

• Boston is the underdog, +190 on the moneyline, while Detroit is a -230 favorite at home.

Tigers vs Red Sox Spread

• The Tigers are 1.5-run home favorites on the runline against the Red Sox. The Tigers are -102 to cover, and the Red Sox are -118.

Tigers vs Red Sox Over/Under

• Tigers versus Red Sox on May 4 has an over/under of 7 runs, with the odds on the over +100 and the under set at -122.

Bet on Detroit Tigers vs. Boston Red Sox on FanDuel today!

Tigers vs Red Sox Betting Trends

• The Tigers have come away with 13 wins in the 23 contests they have been listed as the favorites in this season.
• Detroit has played as a favorite of -230 or more just one time this year and came away with a win in that game.
• The Tigers and their opponents have hit the over in 16 of their 35 games with a total set by oddsmakers this season.
• The Tigers have an against the spread mark of 18-17-0 in 35 games with a line this season.
• The Red Sox have won 27.3% of the games this season they were the underdog on the moneyline (3-8).
• Boston has not played a game this season with moneyline odds of +190 or longer.
• The Red Sox have had an over/under set by oddsmakers 34 times, and have combined with opponents to go over the total in 16 of those games (16-17-1).
• The Red Sox have put together an 11-23-0 record ATS this season (covering just 32.4% of the time).

Tigers Player Leaders

• Kevin McGonigle leads Detroit with an OBP of .407, plus a team-best slugging percentage of .477. He's batting .315 on the season.
• Among qualified hitters in MLB, he is 16th in batting average, 11th in on-base percentage, and 42nd in slugging.
• McGonigle hopes to build on a two-game hitting streak in this matchup. During his last five outings he is hitting .250 with three walks and four RBIs.
• Riley Greene is hitting .290 with eight doubles, four home runs and 21 walks, while slugging .452 with an on-base percentage of .393.
• His batting average is 36th among qualified players, his on-base percentage 18th, and his slugging percentage 56th.
• Dillon Dingler leads Detroit in total hits (26) this season, and 12 of those have gone for extra bases.
• Dingler takes a three-game hitting streak into this game. During his last five outings he is batting .353 with two doubles, a home run, a walk and four RBIs.
• Gleyber Torres is batting .259 with a .389 OBP and 11 RBI for Detroit this season.

Red Sox Player Leaders

• Wilyer Abreu has a .460 slugging percentage, which leads the Red Sox. He's batting .298 with an on-base percentage of .379.
• Including all qualified hitters, he ranks 31st in batting average, while his on-base percentage ranks 35th and he is 52nd in slugging.
• Willson Contreras paces his team with 33 hits and a .387 on-base percentage. He has a batting average of .280 while slugging .492.
• Including all qualified hitters, he is 42nd in batting average, 24th in on-base percentage and 36th in slugging percentage.
• Jarren Duran has five doubles, three home runs and eight walks while hitting .186.
• Caleb Durbin is hitting .165 with six doubles, a home run and 11 walks.

Tigers vs Red Sox Head to Head

• 4/20/2026: 8-6 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/19/2026: 6-2 DET (Favorite: Red Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/18/2026: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/17/2026: 1-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/28/2025: 4-3 BOS (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/27/2025: 2-1 DET (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/26/2025: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/14/2025: 6-5 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 5/13/2025: 10-9 DET (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/12/2025: 14-2 DET (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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