South Alabama vs Louisiana Prediction, Odds, Picks, Best Bets for Week 10 2025

On Saturday in college football, the South Alabama Jaguars are playing the Louisiana Ragin' Cajuns.
Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.
South Alabama vs Louisiana Odds & Spread
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- All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: South Alabama: (-174) | Louisiana: (+144)
- Spread: South Alabama: -3.5 (-115) | Louisiana: +3.5 (-105)
- Total: 52.5 -- Over: (-115) | Under: (-105)
South Alabama vs Louisiana Betting Trends
- Against the spread, South Alabama is 3-5-0 this year.
- As a 3.5-point or greater favorite, South Alabama has one win ATS (1-3) this season.
- This year, five of South Alabama's eight games have gone over the point total.
- Louisiana owns two wins against the spread this year.
- Louisiana has one win ATS (1-3) as a 3.5-point underdog or more this year.
- Louisiana has played seven games this season, and four of them have hit the over.
South Alabama vs Louisiana Prediction & Pick
All college football win probability predictions and picks are according to numberFire.
Prediction: Jaguars win (54.6%)
South Alabama vs Louisiana Point Spread
Louisiana is the underdog by 3.5 points against South Alabama. Louisiana is -115 to cover the spread, and South Alabama is -105.
South Alabama vs Louisiana Over/Under
South Alabama versus Louisiana, on Nov. 1, has an over/under of 52.5, with the over being -115 and the under -105.
South Alabama vs Louisiana Moneyline
South Alabama is a -174 favorite on the moneyline, while Louisiana is a +144 underdog.
South Alabama vs. Louisiana Points Insights
Point Scored (PG) | Points Scored CFB Rank | Points Allowed (PG) | Points Allowed CFB Rank | Average Total | Total Games | |
|---|---|---|---|---|---|---|
| South Alabama | 25.3 | 86 | 29.5 | 101 | 54.0 | 8 |
| Louisiana | 23.5 | 95 | 30.3 | 109 | 48.8 | 8 |
South Alabama vs. Louisiana Game Info
- Game day: Saturday, November 1, 2025
- Game time: 3:30 p.m. ET
- TV channel: ESPN+
- Location: Mobile, Alabama
- Stadium: Hancock Whitney Stadium
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