Reds vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 13

Odds updated as of 6:11 a.m.

The Cincinnati Reds are among the MLB squads in action on Tuesday, up against the Chicago White Sox.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Reds vs White Sox Game Info

• Cincinnati Reds (20-22) vs. Chicago White Sox (12-29)
• Date: Tuesday, May 13, 2025
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and CHSN

Reds vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-198) | CHW: (+166)
• Spread: CIN: -1.5 (-100) | CHW: +1.5 (-120)
• Total: 9 -- Over: (-124) | Under: (+102)

Reds vs White Sox Probable Starting Pitchers

Probable Pitchers: Andrew Abbott (Reds) - 2-0, 2.25 ERA vs Jonathan Cannon (White Sox) - 2-4, 4.09 ERA

This contest's pitching matchup is set, as the Reds will send Andrew Abbott (2-0) to the mound, while Jonathan Cannon (2-4) will take the ball for the White Sox. When Abbott starts, his team is 4-1-0 against the spread this season. Abbott's team is 2-0 this season when he starts and they're favored on the moneyline. The White Sox have gone 3-4-0 ATS in Cannon's seven starts that had a set spread. The White Sox are 1-6 in Cannon's seven starts this season that they were the underdog on the moneyline.

Reds vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (66.6%)

Reds vs White Sox Moneyline

• Chicago is a +166 underdog on the moneyline, while Cincinnati is a -198 favorite at home.

Reds vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Reds. The White Sox are -120 to cover the spread, and the Reds are -100.

Reds vs White Sox Over/Under

• The Reds-White Sox game on May 13 has been given an over/under of 9 runs. The over is set at -124 and the under at +102.

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Reds vs White Sox Betting Trends

• The Reds have come away with nine wins in the 16 contests they have been listed as the favorites in this season.
• Cincinnati has played as a favorite of -198 or more just one time this year and came away with a win in that game.
• Contests with the Reds have gone over the total set by oddsmakers in 18 of 41 chances this season.
• The Reds are 21-20-0 against the spread in their 41 games that had a posted line this season.
• The White Sox have won 12 of the 40 games they were the underdog on the moneyline this season (30%).
• Chicago has a record of 4-16 when playing as a moneyline underdog with odds of +166 or longer (20%).
• In the 41 games oddsmakers have set an over/under for the White Sox, they have combined with opponents to go over the total 19 times (19-20-2).
• The White Sox have put together a 22-19-0 record ATS this season.

Reds Player Leaders

• TJ Friedl has an OPS of .742, fueled by an OBP of .358 and a team-best slugging percentage of .385 this season. He has a .276 batting average.
• Among qualified hitters in baseball, he ranks 48th in batting average, 44th in on-base percentage, and 104th in slugging.
• Elly De La Cruz is hitting .244 with five doubles, six home runs and 17 walks. He's slugging .384 with an on-base percentage of .321.
• Among all qualifying players, he is 97th in batting average, 89th in on-base percentage and 107th in slugging percentage.
• Gavin Lux has 37 hits and an OBP of .377, both of which lead the Reds this season.
• Jose Trevino is batting .310 with a .344 OBP and 10 RBI for Cincinnati this season.
• Trevino has safely hit in two games in a row. During his last five outings he is batting .263 with four doubles and an RBI.

White Sox Player Leaders

• Luis Robert is hitting .186 with three doubles, five home runs and 20 walks. He's slugging .326 with an on-base percentage of .293.
• Including all the qualified hitters in MLB, he is 154th in batting average, 124th in on-base percentage and 141st in slugging percentage.
• Miguel Vargas has a .312 OBP to lead his team. He has a batting average of .215 while slugging .319.
• Including all qualifying hitters, he is 135th in batting average, 102nd in on-base percentage and 145th in slugging percentage.
• Andrew Vaughn is batting .191 with six doubles, five home runs and seven walks.
• Matthew Thaiss is hitting .224 with four doubles, a home run and 18 walks.

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