Reds vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for May 19

Odds updated as of 6:11 a.m.

On Monday in MLB, the Cincinnati Reds are playing the Pittsburgh Pirates.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Reds vs Pirates Game Info

• Cincinnati Reds (24-24) vs. Pittsburgh Pirates (15-32)
• Date: Monday, May 19, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: Fox Sports 1, SportsNet PT, and FDSOH

Reds vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-122) | PIT: (+104)
• Spread: CIN: -1.5 (+146) | PIT: +1.5 (-178)
• Total: 8 -- Over: (-110) | Under: (-110)

Reds vs Pirates Probable Starting Pitchers

Probable Pitchers: Nick Lodolo (Reds) - 3-4, 3.42 ERA vs Mitch Keller (Pirates) - 1-5, 4.15 ERA

The probable starters are Nick Lodolo (3-4) for the Reds and Mitch Keller (1-5) for the Pirates. Lodolo and his team are 5-4-0 ATS this season when he starts. Lodolo's team has a record of 2-3 this season when he starts and they are the favorite on the moneyline. When Keller starts, the Pirates have gone 3-6-0 against the spread. The Pirates are 1-5 in Keller's six starts this season that they were the moneyline underdog.

Reds vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (57.8%)

Reds vs Pirates Moneyline

• The Reds vs Pirates moneyline has Cincinnati as a -122 favorite, while Pittsburgh is a +104 underdog at home.

Reds vs Pirates Spread

• The Reds are 1.5-run road favorites on the runline against the Pirates. The Reds are +146 to cover, and the Pirates are -178.

Reds vs Pirates Over/Under

• An over/under of 8 has been set for Reds-Pirates on May 19, with the over being -110 and the under -110.

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Reds vs Pirates Betting Trends

• The Reds have come away with 11 wins in the 19 contests they have been listed as the favorites in this season.
• Cincinnati has a record of 8-5 in contests when bookmakers favor them by -122 or more on the moneyline.
• Contests with the Reds have gone over the total set by oddsmakers in 18 of 46 chances this season.
• The Reds are 25-21-0 against the spread in their 46 games that had a posted line this season.
• The Pirates have gone 10-20 in games they were listed as the moneyline underdog (winning 33.3% of those games).
• Pittsburgh has gone 8-19 when playing as a moneyline underdog with odds of +104 or longer (29.6%).
• The Pirates have combined with opponents to hit the over on the total 17 times this season for a 17-26-2 record against the over/under.
• The Pirates have an 18-27-0 record against the spread this season.

Reds Player Leaders

• Elly De La Cruz has 46 hits to go with a slugging percentage of .406, both of which rank first among Cincinnati hitters this season. He has a .246 batting average and an on-base percentage of .317.
• Among qualified hitters, he ranks 99th in batting average, his on-base percentage ranks 101st, and he is 90th in slugging.
• TJ Friedl is hitting .265 with seven doubles, a triple, three home runs and 23 walks, while slugging .373 with an on-base percentage of .358.
• He is 60th in batting average, 46th in on-base percentage and 116th in slugging in MLB.
• Gavin Lux has 43 hits this season and a team-best OBP of .379.
• Austin Hays has been key for Cincinnati with 26 hits, an OBP of .363 plus a slugging percentage of .590.
• Hays brings a five-game hitting streak into this matchup. In his last five games he is hitting .333 with two doubles, a home run, a walk and four RBIs.

Pirates Player Leaders

• Oneil Cruz has totaled 31 hits, a team-high for the Pirates. He's batting .223 and slugging .432 with an on-base percentage of .349.
• Including all qualified hitters, he ranks 129th in batting average, while his on-base percentage is 57th and he is 70th in slugging.
• Andrew McCutchen has seven doubles, three home runs and 20 walks while hitting .248. He's slugging .368 with an on-base percentage of .348.
• He is currently 94th in batting average, 61st in on-base percentage and 121st in slugging percentage among all qualifying hitters.
• Bryan Reynolds is hitting .203 with five doubles, six home runs and 16 walks.
• Ke'Bryan Hayes leads his team with a .311 slugging percentage.

Reds vs Pirates Head to Head

• 4/13/2025: 4-0 CIN (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 4/12/2025: 5-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/11/2025: 5-3 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/22/2024: 2-0 PIT (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/21/2024: 7-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/20/2024: 8-3 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/25/2024: 4-3 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/24/2024: 10-2 CIN (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/23/2024: 6-5 PIT (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/22/2024: 7-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)

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